THE SPECIFIC FEATURES OF THE TUBERCULOSIS EPIDEMIC SITUATION AT THE REGIONAL LEVEL AFTER IMPLEMENTATION OF FEDERAL TARGET PROGRAMS

Objective. To study changes in the epidemic situation when implementing the federal target program «Prevention and Control of Social Diseases (2007-2011)» in the Kursk Region and to identify priority factors of its formation. Materials and methods. The 2000-2013 data of statistical reporting (Form No. 8 «Information on active tuberculosis cases», Form No. 33 «Information on tuberculosis patients», and forms of specialized statistical reporting in compliance with Order No. 50 issued by the Min istry of Health of Russia on February 13, 2004) were analyzed. Results. In 2007 to 2013, there was a decrease in the incidence of tuberculosis. In 2011, there was a rise in the percent of detected patients with multidrug resistant tuberculosis in both the Kursk Region and the Russian Federation as a whole. In 2013, the incidence of primary multidrug resistant tuberculosis increased up to 4.5per 100 000population versus 1.8per 100 000 in 2010. Conclusion. Drug resistance in Mycobacterium tuberculosis is now one of the major factors limiting the efficiency of tuberculosis chemotherapy, which requires that new antituberculosis agents should be designed and introduced for the treatment of patients with multidrug resistant tuberculosis.

tuberculosis, detection, morbidity, mortality, multidrug resistance