Modern accents in the diagnostics of inflammatory diseases of the pelvic organs

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The clinical course of inflammatory diseases of the pelvic organs (PID) is very diverse, certain difficulties in the diagnosis of acute inflammation can be caused with a sufficient combination of probable symptoms. Most of the patients are subacute or chronic course of the disease. Not timely diagnosis and incorrectly prescribed treatment favorably affects the movement of the inflammatory process in the upper genital tract.

The diagnosis of PID in emergency rooms and clinics is often based on clinical criteria, with or without additional laboratory and visual tests. Clinical data have a sensitivity of 87% and a specificity of 50% versus 83% sensitivity and 26% specificity of endometrial culture.

The presence of leukocytosis in peripheral blood, elevated ESR and/or the level of C-reactive protein are also markers of inflammation and may be an indicator of the severity of the disease, but they do not serve as specific signs of PID.

The frequency of occurrence of inflammatory diseases of the reproductive system and common complications can lead to a pronounced imbalance in the reproductive potential of not only women, but also the population. The presence of a predominance of the chronic course of the disease, specialists of different profiles should have a sense of suspicion of the probable presence of an infectious agent in the pelvic organs in women of reproductive age in the presence of various non-specific complaints from the lower abdomen and the absence of other obvious reasons.

Untimely treatment of PID is closely associated with the deterioration of the patient’s condition and long-term complications.

To achieve successful attempts to prevent complications of PID, it is practically not possible, despite numerous studies.

The widely used routine laboratory examination methods have diagnostic value only in patients with pronounced symptom complexes, while in the chronic course their significance is small.

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About the authors

M. S. Selikhova

“Volgograd State Medical University” of the Ministry of Health of the Russia

Author for correspondence.

Russian Federation, Volgograd

P. A. Soltys

“Volgograd State Medical University” of the Ministry of Health of the Russia


Russian Federation, Volgograd


  1. Belova A.V., Astsaturova O.R., Aleksandrov L.S. The importance of genital mycoplasmas (U. parvum, U. urealyticum, M. hominis, M. ge- nitalium) in the development of infectious complications of pregnancy, childbirth, the postpartum and early neonatal period. Rossiyskiy Vestnik Akushera-Ginekologa. 2015; (2): 85. (in Russian)
  2. Bulanov M.N. Ultrasound Gynecology: The course of lectures in 3 volumes. T. 3 [Ul’trazvukovaya ginekologiya: Kurs lektsiy v 3-kh tomakh. Tom 3]. Moscow: Vidar; 2011. (in Russian)
  3. Bugg C.W., Taira T., Zaurova M. Pelvic inflammatory disease: Diagnosis and treatment in the emergency department [digest]. Emerg. Med. Pract. 2016;18(12 Suppl Points & Pearls): S1-S2.
  4. Canadian Guidelines on Sexually Transmitted Infection (with current updates and errata). January 2010. http: //
  5. CDC. Pelvic Inflammatory Disease (PID). Atlanta, GA: Department of Health and Human Services; 2015.
  6. Dovletkhanova E.R. Inflammatory diseases of the pelvic organs (the role of STIs in the development of PID). Meditsinskiy sovet. 2013; (8): 62. (in Russian)
  7. Kira E.F., Dushkina E.A., Badikova N.S. The biological role of vaginal acidity. Stability mechanisms and correction methods. Akusherstvo i ginekologiya. 2013; (3):102. (in Russian)
  8. Kungurtseva E.A., Popkova S.M., Leshchenko O.Ya. Mutual formation of microflora of mucous membranes of open cavities of various biotopes in women as an important factor in their reproductive health. Vestnik Rossiyskoy akademii meditsinskikh nauk. 2014; (9‒10): 27. (in Russian)
  9. Lin H.W., Tu Y.Y., Lin S.Y. Risk of ovarian cancer in women with pelvic inflammatory disease: a population-based stady. Lancet Oncol. 2011; 12 (9): 900-4.
  10. Sbib T.Y., Gaydos C.A., Rotbman R.E. Poor Provider Adberence to the Center s for Disease Control and Prevention Treatment Guidelines in US Emergency Department Visits With a Diagnosis of Pelvic Inflammatory Disease. Sex. Trans. Dis. 2011; 38(4): 299-305.
  11. Greydanus D.E., Dodich C. Pelvic inflammatory disease: a poignant, perplexing, potentially preventable problem for patients and physicians. Curr. Opin. Pediatr. 2015; 27: 92-9.
  12. Ford G.W., Decker C.F. Pelvic inflammatory disease. Dis. Mon. 2016; 62: 301-5.
  13. Workowski K., Berman S. Center for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines. MMWR Recom. Rep. 2010; 59 (RR-12): 1-110.
  14. Morbidity and Mortality Weekly Report. 2010; vol. 59, no. RR-12, View at Google Scholar.
  15. US Preventive Services Task Force. Screening for chlamydial infection: recommendations and rationale. Am. J. Prev. Med. 2001; 20: 90-4.
  16. Meyer T. Diagnostic Procedures to Detect Chlamydia trachomatis Infections. Microorganisms. 2016; 4: 25.
  17. Soper D.E. Pelvic inflammatory disease. Obstet. Gynecol. 2010; 116 (2 Pt 1):419-28. doi: 10.1097/AOG.0b013e3181e92c54
  18. Serov V.N., Dubnitskaya L.V., Tyutyunnik V.L. Pelvic inflammatory diseases: diagnostic criteria and treatment principles. Russkiy meditsinskiy zhurnal. Mat’ i ditya. 2011;19 (1): 46-50. (in Russian)
  19. Colombel J.F., Shin A., Gibson P.R. AGA Clinical practice update on functional gastrointestinal symptoms in patients with inflammatory bowel disease: expert review. Clin. Gastroenterol. Hepatol. 2019;17(3): 380-90.e1.
  20. Elankova N.N. New approaches to the diagnosis and treatment of inflammatory diseases of the pelvic organs: Diss. Ivanovo; 2011. (in Russian)
  21. Kuz’min V.N., Adamyan L.V., Pustovalov D.A. Sexually transmitted infections and women’s reproductive health.[Infektsii, peredavayemyye polovym putem, i okhrana reproduktivnogo zdorov’ya zhenshchin]. Moscow; 2010. (In Russian)
  22. Serov V.N., Sukhikh G.T., eds. Medicines in obstetrics and gynecology. Ed. 3rd corrected and add. Moscow: GEOTAR-Media; 2011. (in Russian)
  23. Shurshalina A.V. Pelvic inflammatory diseases: modern treatment tactics. Ginekologiya. 2011; 13(5): 23-6. (in Russian)
  24. Radzinskiy V.E., Fuks A.M. Gynecology: Textbook. [Ginekologiya: Uchebnik]. Moscow: GEOTAR-Media; 2014. (in Russian)
  25. Sidorova I.S., Makarov O.V., Manukhin I.B. Prevention and treatment of intrauterine infections: Guidelines. [Profilaktika i lecheniye vnutriutrobnykh infektsiy: Metodicheskiye rekomendatsii]. Moscow; 2007. (in Russian)
  26. Sukhikh G.T., Shurshalina A.V. Chronic Endometritis: A Guide. [Khronicheskiy endometrit: Rukovodstvo]. Moscow: GEOTAR-Media; 2010. (in Russian)
  27. Utkin E.V. Clinic, diagnosis and therapy of inflammatory diseases of the uterine appendages of a non-specific etiology. [Klinika, diagnostika i terapiya vospalitel’nykh zabolevaniy pridatkov matki nespetsificheskoy etiologii]. Kemerovo: Kuzbass; 2010. (in Russian)
  28. Kulakov V.I., Serov V.N., Abakarova P.R. et al. Rational pharmacotherapy in obstetrics and gynecology: Guide for practitioners. [Ratsional’naya farmakoterapiya v akusherstve i ginekologii: Rukovodstvo dlya praktikuyushchikh vrachey]. Moscow: Litterra; 2015. (in Russian)
  29. Tikhomirov A.L., Sarsaniya S.I. The tactics of choosing an antibiotic for the treatment of inflammatory diseases of the pelvic organs. Ginekologiya. 2009; 11(5): 34-7. (in Russian)
  30. Radzinskiy V.E., Orazmuradov A.A., eds. Early pregnancy. [Ranniye sroki beremennosti]. Moscow: Status praesens; 2009. (in Russian)
  31. Kuz’min V.N., Guseynzade M.I. Modern views on the role of mycoplasma infection in the structure of inflammatory diseases of the pelvic organs. Consilium medicum. 2011; 13(6): 40-5. (in Russian)
  32. Serov V.N., Sukhikh G.T., Baranov I.I., Pyregov A.V., Tyutyunnik V.L., Shmakov R.G. Emergencies in Obstetrics: A Guide for Physicians. [Neotlozhnyye sostoyaniya v akusherstve: Rukovodstvo dlya vrachey]. Moscow: GEOTAR-Media; 2010. (in Russian)
  33. Eliseyeva E.V., Torgovitskaya I.P., Khamoshina M.B. Empirical antibiotic therapy of acute salpingo-oophoritis.[Empiricheskaya antibiotikoterapiya ostrogo sal’pingooforita]. Vladivostok: Dal’nauka; 2009. (in Russian)
  34. Gomberg M.A. The place of fluoroquinolones in the modern treatment of sexually transmitted infections. Consilium medicum. 2011; 13(6): 12-4. (in Russian)
  35. Jaiyeoba O., Lazenby G., Soper D.E. Recommendations and rationale for the treatment of inflammatory disease. Expert Rev. Anti Infect. Ther. 2011; 9 (1): 61-70.
  36. Kreisel K., Torrone E., Bernstein K. et al. Prevalence of pelvic inflammatory disease in sexually experienced women of reproductive age — United States, 2013–2014. MMWR Morb. Mortal. Wkly. Rep. 2017; 66: 80-3.
  37. Witkin S.S., Minis E., Athanasiou A., Leizer J., Linhares I.M. Chlamydia trachomatis: the Persistent Pathogen. Clin. Vaccine Immunol. 2017; 24(10). doi: 10.1128/CVI.00203-17
  38. Park S.T., Lee S.W., Kim M.J., Kang Y.M., Moon H.M., Rhim C.C. Clinical characteristics of genital chlamydia infection in pelvic inflammatory disease. BMC Womens Health. 2017;17(1): 5.
  39. Soper D.E. Pelvic inflammatory disease. Obstet. Gynecol. 2010; 116 (6): 1459.
  40. Ushkalova E.A. Place of azithromycin in the treatment of inflammatory diseases of the pelvic organs. Ginekologiya. 2011; 13(3): 44-9. (in Russian)



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