Acne as an interdisciplinary problem

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The purpose of research is the study of causes of the formation of acne in women. There were examined 100 female patients. There were investigated hormonal parameters of blood serum characterizing the androgen status (level of testosterone, dehydroepiandrosterone-sulfate, 17-oxyprogesterone, androstenedione and sex hormone binding globulin (SHBG). Biochemical hyperandrogenism was excluded in all patients. As a result of serodiagnosis by enzyme immunoassay (ELISA) in the course of the examination of the gastrointestinal tract in all cases there were revealed positive results of IgG antibodies to Helicobacter pylori (HP). Inclusion of the eradication scheme into the standard acne therapy confirmed the substantial contribution of the pathology of the gastrointestinal tract caused by HP infection in the development of acne. This allows to recommend the inclusion of both (ELISA IgG) and treatment of HP infection in the standards of the examination and treatment ofpatients with diagnosis.

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About the authors

A. V Novoselov

I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation

V. S Novoselov

I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation

Elena A. Sosnova

I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation
MD, PhD, DSci., Professor of the Department of Obstetrics and Gynecology No 1, Medical Faculty of the I.M. Sechenov First Moscow State Medical University

V. A Kaptil’nyy

I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation


  1. Rodriguez-Cavallini E., Vargas-Dengo P. Etiologyi abacteriana y susceptiblidada antibioticos en pacientes con acne. Rev. Biomed. 2004; 15: 101-6.
  2. Федеральные клинические рекомендации по ведению больных АКНЕ Российского общества дерматовенерологов и косметологов. М.; 2015.
  3. Rzany B., Kahl C. Epidemiology of acne vulgaris. J. Dtsch. Dermatol. Ges. 2006; 4(1): 8-9.
  4. Stathakis V., Kilkenny M., Marks R. Descriptive epidemiology of acne vulgaris in the community. Austr. J. Dermatol. 1997; 38(3): 115-23.
  5. Leyden J., Preston N., Osborn C., Gottschalk R.W. In-vivo effectiveness of adapalene 0.1%/ benzoyl peroxide 2.5% gel on antibiotic-sensitive and resistant propioni bacterium acnes. Clin. Aesthet. Dermatol. 2011; 4(5): 22-6.
  6. Cunliffe W.J. Акне. В кн.: Кацамбас А.Д., Лотти Т.М. (ред.). Европейское руководство по лечению дерматологических болезней. 3-е изд.: Пер. с англ. М.: МЕДпресс-информ; 2014.
  7. Кубанова А.А. (ред.). Российское общество дерматовенерологов. Клинические рекомендации по ведению больных акне. М.: ДЭКС-Пресс; 2010.
  8. Юцковская Я.А., Тарасенкова М.С., Наумчик Г.А. Рациональность применения новых лекарственных форм изотретиноина при системной терапии тяжелых форм угревой болезни. Клиническая дерматология и венерология. 2010; (4); 51-4.
  9. Карр Б., Блэкуэлл Р., Азиз Р. (ред.). Руководство по репродуктивной медицине: Пер. с англ. под общей ред. И.В. Кузнецовой. М.: Практика; 2015.
  10. Hammerstein J. (Ed.). Possibilities and Limits of Endocrine Therapy. Androgenisation in Women. Amsterdam: Excerpta Medica; 1980: 221-34.
  11. Потекаев Н.Н. (ред.). Акне и розацеа. М.: Бином; 2007.
  12. Адаскевич В.П. Акне вульгарные и розовые. Н. Новгород; 2003.
  13. Goodman G.J., Baron J.A. The management of postacne scarring. Dermatol. Surg. 2007; 33 (10): 1175-88.
  14. Mallon E., Newton J.N., Klassen A. et al. The quality of life in acne: a comparison with general medical conditions using generic questionnaires. Br. J. Dermatol. 1999; 140 (4): 672-6.
  15. Иванов О.Л. (ред.). Кожные и венерические болезни: Учебник для вузов. М.: ШИКО; 2006.



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