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Atypical hemolytic-uremic syndrome being referred to autoimmune diseases appears to be one of the most severe forms of thrombosis and microangiopathy. Difficulties in diagnosis cause a delay in pathogenetic therapy, which causes a high maternal mortality rate. Pathogenetic therapy with eculizumab, suppressing the terminal activity of complement, may contribute to the recovery of blood coagulation properties, but the long-term prognosis for chronic renal failure remains unfavorable. The article deals with a clinical case confirming this conclusion.

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About the authors

N. A Zharkin

Volgograd State Medical University, Ministry of Health of Russia

Volgograd, 400131, Russian Federation

M. E Statsenko

Volgograd State Medical University, Ministry of Health of Russia

Volgograd, 400131, Russian Federation

M. M Stazharova

Volgograd Regional Clinical Hospital No. 1

Volgograd, 400081, Russian Federation

Natalia A. Burova

Volgograd State Medical University, Ministry of Health of Russia

Volgograd, 400131, Russian Federation
MD, Ph.D., Associate Professor, Department of Obstetrics and Gynecology, Volgograd State Medical University, Volgograd, 400131, Russian Federatio

S. A Prokhvatilov

Volgograd Regional Clinical Hospital No. 1

Volgograd, 400081, Russian Federation


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