Vol 4, No 1 (2017)

Among the various neuroendocrine disorders hyperprolactinemic syndrome (HLS) proves to be of great scientific and practical importance. In the clinical lecture there are presented data on etiology and pathogenesis of HLS, its prevalence rate in the population. There are presented the classification, clinical variants, diagnostic criteria for HLS and the algorithm of examination of patients. There is considered the concept of the management of HLS cases, features of the course and management of pregnancy in this type of pathology.

In the article there were analyzed methods of the treatment of uterine myoma patients, including approaches allowing to save the organ. On the basis of the literature there was made a conclusion about the need for further research on the effectiveness of treatment of uterine fibroids by focused ultrasound (FUS) ablation, with taking into account the interest of patients in organ(uterus)-sparing and commitment in the most of patients to preserve their reproductive function.

In an article there is analyzed the maternal mortality rate from sepsis in the postpartum period in the Tula region over the period of2001-2015 Sepsis during the intrapartum and postpartum period takes the 3rd place in the structure of the maternal mortality rate in the Tula region, due to sepsis 3 women (8.6%) died out of 35 lethal cases during that period. In absolute numbers, from sepsis every 5 years the 1 woman died, but there was a trend to growth of the portion of this complication from 6.2% (2001-2005) to 14.3% (2011-2015). Among the cases who dead there was the primigravida, 2 multigravida (3rd and 4th pregnancy), the second birth was in 2 cases. There were 2 multiparous residents of the village. In the 1 case sepsis was developed after the delivery, the 1 patient had undergone to cesarean section, 1 pregnant woman died. The death in hospital took place in 2 cases, 1 patient died outside the hospital. The decline of the maternal mortality rate from sepsis directly depends on timely diagnosis, early and adequate treatment in the each particular situation.

The aim of the study is to estimate the contribution of radical surgery on the uterus and appendages in the formation of the metabolic syndrome (MS). Material and methods. The study involved 100 patients, who underwent surgery on the pelvic organs in the extent of subtotal hysterectomy with bilateral adnexectomy or without it. Within 12 months after the operation in the dynamics there were investig TED changes in the body mass index (BMI), blood pressure (BP) and carbohydrate metabolism. Results. The removal of the uterus was established to fail to influence on the increase in body mass index, however, it has an impact on the indices of carbohydrate metabolism, in particular - on the change in the HOMA-IR index, and systolic blood pressure. The persistent increase in systolic blood pressure appeared to be the only index identified by the 12th month of the observation.