Early diagnostics of the cardiovascular breaches of patients with myotonic dystrophy



Cite item

Full Text

Abstract

According to the register of medical genetic consultation of Samara Regional Clinical Hospital M.I. Kalinin 89 patients with myotonic dystrophy are registered. A group of 24 patients between 15 and 20 years of age with the aim of early detection of changes in the cardiovascular system was selected and examined. In 75% of ECG changes in the form of conduction disturbances were registered. In 33,3% patients had changes on echocardiography. These changes can be assessed as subcompensated stage of cardiomyopathy.

About the authors

V V Chernikova

References

  1. Наследственные болезни нервной системы / под ред. Ю.Е. Вельтищева., П.А. Темина. - М.: Медицина. 1998. - 495 с.
  2. Болезни нервной системы / под ред. Н.Н. Яхно., Д.Р. Штульмана. - 3-е изд. - М.: Медицина, 2003. - 743 с.
  3. Наследственные болезни: национальное руководство / под ред. Н.П. Бочкова, Е.К. Гинтера., В.П. Пузырева. - М.: Гэотар-Медиа, 2012. - 522-525 с
  4. Ono S., Takahashi K., Jinnai K. et al. Loss of serotonin-containing neurons in the raphe of patientswith myotonic dystrophy: a quantitative immunohistochemical study and relation to hypersomnia // Neurology. - 1998. - Vol. 50. - P. 535-538.
  5. Наследственные болезни нервной системы / под ред. Ю.Е. Вельтищева., П.А. Темина. - М.: Медицина. 1998. - 495 с.
  6. Merlevede K., Vermander D., Theys P. et al. Cardiac involvement and CTG expansion in myotonic dystrophy // J. Neurol. - 2002. - Vol. 249, № 6. - P. 693-698.
  7. Nigro G., Politano L., Nigro V. et al. Mutation of dystrophiс gene and cardiomyopathy // Neuromuscul. Dis. - 1994. - Vol. 4. - P. 371-379.
  8. Болезни нервной системы / под ред. Н.Н. Яхно., Д.Р. - 3-е изд. - М.: Медицина, 2003. - 743 с.
  9. Кеннет Л. Джонс. Наследственные синдромы по Дэвиду Смиту. Атлас-справочник. Пер. с англ. - М.: Практика, 2011. - 254-255 с.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2014 Chernikova V.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies