Noninvasive diagnosis of renal osteodystrophy (literature review)


This review concerns to “Chronic kidney disease-mineral and bone disorder” (CKD-MBD). This term is used to describe a set of biochemical abnormalities, bone disturbances that may lead to fractures, and extraskeletal calcification in soft tissues and arteries seen in CKD. Renal osteodystrophy (ROD) is a part of the CKD-MBD, the bone biopsy is the gold standard to diagnose it, but it is not clinically practical for studying continuous changes in bone morphology. The recent studies concern to the noninvasive diagnosis of renal osteodystrophy to predict fracture risk and optimize the therapy.


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