Email this article Dependence of lactate dehydrogenase activity on the method of urinary bladder cancer treatment
- Authors: Nizamova RS1
-
Affiliations:
- Issue: Vol 11, No 1-2 (2011)
- Pages: 163-166
- Section: Articles
- URL: https://aspvestnik.ru/2410-3764/article/view/24907
- DOI: https://doi.org/10.17816/2072-2354.2011.0.1-2.163-166
- ID: 24907
Cite item
Full Text
Abstract
There was conducted the investigation of lactate dehydrogenase (LDG) activity in blood serum and urine of patients having nonmalignant and malignant tumors of urinary bladder after various treatment methods. The total activity of LDG was evaluated by kinetic method with the help of a special set of reagents. After polychemical therapy there was revealed the decrease of LDG activity in blood serum and urine both among men and women, but only after surgical methods there is no so distinct decrease of ferment activity. After complex treatment, as well as after combination of radiotherapy and surgical method the decrease of fermentative activity was revealed in urine.
References
- Boyland E. Биохимические механизмы индукции рака мочевого пузыря // Механизмы канцерогенеза. - М., 1961. - С.279 - 296; Mattea E. Les processus biochimiques de la cancerogenese vesicale // Acta urol.belg. - 1960. - Vol. 28, № 3. - P. 313-330.
- Sheng K.H., Yao Y.C., Chuang S.S. Search for the tumor-related proteins of transition cell carcinoma in Taiwan by proteomic analysis // Proteomics. - 2006. - Vol. 6, № 3. - P. 1058-1065.
- Shimazui T., Akaza H. Significance of current bio-and molecular-markers in urological cancers // Gan To Kagaku Ryoho. - 2004. - Vol. 31, № 7. - P. 1008-1014.
- Yang T.B., Zeng F.H., Sun Z.Q. Prognostic factors for primary superficial transitional cell carcinoma of the bladder: a retrospective cohort study // Chin Med J (Engl). - 2006. - Vol. 119, № 21. - P. 821-828.
- Youssef E.M., Wanibuchi H., Miori S. Elevation of urinary enzyme levels in rat bladder carcinogenesis // Carcinogenesis. - 1999. - Vol. 20, № 7. - P. 1247-1252.
- Lazzarino G., Viola A.R., Mulieri L. Prevention by fructose-1,6-bisphosphate of cardiac oxidative damage induced in mice by subchronic doxorubicin treatment // Cancer Research. - 1987. - Vol. 47, № 24. - P. 6511-6516.
- Hilf R., Smail D.B., Murant R.S. Hematoporphyrin derivative-induced photosensitivity of mitochondrial succinate dehydrogenase and selected cytosolic enzymes of R3230AC mammary adenocarcinomas of rats // Cancer Research. - 1984. - Vol. 44, № 4. - P. 1483-1488.
Supplementary files
