Aspirantskiy Vestnik PovolzhiyaAspirantskiy Vestnik Povolzhiya2072-23542410-3764Samara State Medical University2435910.17816/2072-2354.2015.0.1-2.121-125Research ArticleAssesment of local tumor control after radiofrequency ablation in patients with lung cancerKorolevaO L-KorolevD G-15032015151-212112511032020Copyright © 2015, Koroleva O.L., Korolev D.G.2015Radiofrequency ablation (RFA) in primary and metastatic lung cancer is a relatively new medical procedure, and currently there are no clear criteria for assessing the changes occurring as a result of RFA. It is necessary to define a set of features characterizing the zone of postablation lesion and subsequent fibrosis formation to estimate the success of this minimally invasive surgery and local control of dynamic changes in the lung. From April 2008 to December 2012 in Samara regional clinical oncology center radiofrequency thermoablation of lung tumors was performed on 306 lung nodules in 221 patients with primary and metastatic lung tumors. All patients underwent computed tomography (CT) before and after RFA. The authors have developed criteria for evaluating postablation changes based on the analysis of the data.peripheral lung tumornon-small cell lung cancerradiofrequency ablationRFAcomputed tomographyпериферическая опухоль легкогонемелкоклеточный рак легкогорадиочастотная абляцияРЧАрентгеновская компьютерная томография[Brambilla E, Travis WD, Brennan P, et al. Lung cancer / In: Stewart BW, Wild CP. eds. World Cancer Report // International Agency for Research on Cancer.- 2014. P.350-61.][Ginsberg R.J., Rubinstein L.V. Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer // The Annals of Thoracic Surgery. - 1995. 60(3): 615-623.][Bach P.B., Cramer L.D., Warren J.L., Begg C.B. Racial differences in the treatment of early-stage lung cancer // The New England Journal of Medicine. - 1999. 341(16): 1198-1205.][Vrdoljak E., Miše K., Sapunar D., Rozga A., Marušić M. Survival analysis of untreated patients with non-small-cell lung cancer // Chest. - 1994. 106(6):1797-1800.][Долгушин Б.И., Косырев В.Ю., Рампрабанант С. Радиочастотная аблация в онкологии // Практическая онкология. - 2007. № 4. С 219-227][Dupuy DE, Zagoria RJ, Akerley W, Mayo-Smith WW, Kavanagh PV, Safran H. Percutaneous radiofrequency ablation of malignancies in the lung // The American Journal of Roentgenology. 2000. 174(1): 57-59][Каганов О.И., Козлов С.В., Кутырёва Ю.Г., Труханова И.Г. Результаты паллиативного хирургического лечения метастазов колоректального рака в легкие // Паллиативная медицина и реабилитация. - 2011. № 3. С. 31-33][Королев Д.Г., Скупченко А.В., Скобельцов Д.А., Королева О.Л. Оценка местного контроля опухоли легкого после радиочастотной абляции. Совершенствование медицинской помощи при онкологических заболеваниях, включая актуальные проблемы детской гематологии и онкологии. Национальная онкологическая программа. - 2009. С. 249.][Hiraki T., Gobara H., Iishi T.et al. Percutaneous radiofrequency ablation for clinical stage I non-small cell lung cancer: results in 20 nonsurgical candidates // The Journal of Thoracic and Cardiovascular Surgery. -2007. Vol. 134.№. 5. Р.1306-1312.][Detterbeck FC, Mazzone PJ, Naidich DP, et al. Screening for lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines // Chest. - 2013. Vol. 143. P. 78-92.]