Vol 12, No 1-2 (2012)

Articles
Identificationof diastolic dysfunction ofthe right ventricle at stage Iat hypertensive disease(clinical case)
Artem'eva I.V., Artemyev I.V.
Abstract
A case of essential hypertension (EH) stage I in a man at the age of 30 without concomitant clinically significant pathology is presented. During the echocardiographic examination (echocardiography), the standard method has been found diastolic dysfunction (DD) of the right ventricle (RV). At the preclinical stage of structural and functional remodeling of the heart at stage I of EH, before the right ventricular hypertrophy (RVH), diastolic dysfunction (DDF) of the left ventricle (LV) and left ventricular hypertrophy (LVH) in the patient who had DDF RV type of abnormal relaxation.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):9-11
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The galectin-3 valuein nitrosative stress assessment incells of heart atpatients withchronic heart failure
Berezin I.I., Berezin I.I.
Abstract
In the article the results of definition of plasma level galectin-3 and indicators nitrosative stress in patients with chronic heart failure of ischemic etiology. Data of correlation analysis of the contents of 3-nitrothyrosinum, extracellular superoxide dismutase and plasma level galectin-3 in the examined patients are presented.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):12-15
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Dynamics of cardio-renalrelationship in patientswith CHF FC I-IIIundergone surgicalmyocardial revascularization
Bolotov D.V., Bolotov D.V.
Abstract
The paper presents the results of a comparative study of structural and functional parameters of cardiac performance and functional state of kidneys in patients with CHF FC I-III, after myocardial infarction. In patients with heart failure who underwent surgical revascularization, compared with patients who received only medical treatment, revealed the better indicators of systolic and diastolic cardiac function, and also recorded an improvement in tubular, glomerular renal function and reducing microalbuminuria.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):16-20
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Kinetics of musculartype arteries in patients with diabetestypes 1 and 2
Garanin A.A., Garanin A.A.
Abstract
This is a study of biomechanics of muscular type arteries through a computer sphygmography in patients with diabetes types 1 and 2. The study included 60 diabetic patients and 40 healthy individuals. All respondents were divided into 3 groups: group 1 (control) were apparently healthy people 2 - patients with type 1 diabetes, 3 - patients with type 2 diabetes. The study assessed the speed characteristics of the arterial wall displacement and the duration of the phases of the vascular bed. Analysis of the kinetics parameters of the great arteries showed the common qualitative and quantitative changes in propulsive activity of the vascular wall in patients of both types of diabetes. However, in type 2 diabetes these changes are more marked.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):21-24
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Hypertensivecrisis: effectiveness medicinetherapy assessmentat pre-hospital medical care
Zinatullina D.S., Zinatullina D.S.
Abstract
The analysis of statistical data by MMU Center Ambulance Samara-city in 2008, 2009, 2010, revealed that the number of calls about the HC is steadily increasing, hospitalization rates have decreased in 2010. A retrospective analysis of the effectiveness of treatment of patients with uncomplicated hypertensive crisis in 3487 Center Ambulance calls, cards (Form 110u) for the period 2008 - 2010 (the month of June), at the age of 18 to 65 years who have received pre-hospital medical care. As a result of which, it was noted that doctors increasingly began to use modern injectable antihypertensive drugs - ACE inhibitors, ƒ-blockers, ƒ-blockers, at least - ƒ-blockers and centrally acting blockers of Ca channels.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):25-28
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Adiponectinemia inhypertensive patients depending oncardiovascular complications risk
Kiseleva E.V., Kiselyova E.V.
Abstract
Purpose - a comparative investigation of the concentration of adiponectin in hypertensive patients with varying degrees of risk of cardiovascular complications. Materials and Methods. 68 patients with I, II grade arterial hypertension aged 35 to 56, divided into 3 groups depending on the risk of development of cardiovascular complications, underwent examination, including echocardiography, ultrasound dopplerography of brachiocephalic vessels , daily blood pressure monitoring, lipid spectrum, glucose level and adiponectin concentrations in blood serum. Results. In hypertensive patients with low risk of cardiovascular complications the concentration of adiponectin decreased by 32% (p <0,05) compared with those in the control group. Statistically significant negative correlation between adiponectin and low density lipoproteins levels (r = - 0,234), triglycerides (r = - 0,518), body mass index (r = - 0,554) indicates the relationship of inflammatory processes and the impairment of lipid metabolism in hypertensive patients with average risk of cardiovascular complications. In the subgroups of high risk patients the level of adiponectin was significantly low.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):29-32
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The influenceof implantationcava filter on the hospitaltreatment resultsof patients withpulmonary embolismand a high-intermediate risk
Kurakina E.A., Kurakina E.A.
Abstract
The article devoted to the study of pulmonary embolism and a high-intermediate risk in 117 patients ranging in age from 48,5 to 65,3 treated at the Samara regional clinical cardiology dispensary. An assessment of the influence of implantation cava filter in the inferior vena cava in addition to standard therapy with heparin or thrombolytic on the hospital treatment result. It is shown that the implantation of cava filter does not influence on the degree of pressure reduction in pulmonary artery applied by standard methods of treatment and does not contribute to the development of a higher incidence of residual pulmonary hypertension at the time of discharge from hospital, while reducing hospital mortality rate regardless of the main and common method of treatment (thrombolytic therapy or standard heparin one).
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):33-38
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The gender-geneticassessment of frequencyoccurrence of diastolicdysfunction and types of hypertonicremodeling in patientswith controlledand uncontrolledarterial hypertension
Mel'nikova M.A., Olezov N.V., Mel'nikov A.A., Melnikova M.A., Olezov N.V., Melnikov A.A.
Abstract
In this investigation there was revealed the interconnection of the hypertonic remodeling type and the difficulty of breaking diastolic function from genotypes characterizing the flow of arterial hypertension. 76 persons have been investigated: 42 persons with controlled arterial hypertension, 34 persons with uncontrolled arterial hypertension. All patients were compared by age and sex. The investigation of echocardiography by using the apparatus Medison Sonoace 8000 was conducted. The molecular genetic investigation with determining genotypes of polymorphic genes ACE, AGT2R1, eNos was also conducted for all patients. So, the connection of diastolic dysfunction of the heart at women with uncontrolled arterial hypertension is associated with concentric hypertrophy of the left ventricle. The difficulty of the diastolic function and the prognosticly unfavourable type of remodeling heart are associated with genotypes: ACE - II, AGT2R1 - AG, eNos - ab.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):39-42
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The lengthof service influence on course severityof essential arterial hypertensionin locomotive team employees
Obydennikova O.N., Obydennikova O.N.
Abstract
The article provides assessment of the impact of work experience on the progress and course of essential arterial hypertension in locomotive team employees. The survey group consists of 160 patients Samara railway station hospital based on the Russian railways including 120 employees of locomotive teams with essential arterial hypertension stage I-II and 40 railway employees from other occupation, which is not related to train safety (engineers and office employees) without cardiovascular disease. It is shown that the severity of essential arterial hypertension depends on the duration of the working experience.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):43-45
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Effectivenessof restoring treatmentof patients with acutemyocardial infarctionat polyclinic stage
Polyaeva L.V., Polyaeva L.V.
Abstract
Step by step complex cardiological rehabilitation is the effective method of the restoring treatment of patients with acute myocardial infarction. It contributes to an increase of the physical capacity for work, improves the clinical course of disease, slows down the progression of atherosclerosis, stabilizes psychological status and it restores the patients ability to work. The analysis of the results of the rehabilitation of patients with acute myocardial infarction in 14 years (from 1997 until 2010) under the conditions of the department of the restoring treatment of the polyclinic ¹15 of Samara is presented.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):46-50
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The diagnosticvalue of the leukocytic indices ofcellular reactivity inan assessment ofmyocardial infarction healing
Ragozina E.Y., Ragozina E.Y.
Abstract
Predictive value of the integral leukocytic indices on the basis of leukocyte counts of peripheral blood in 400 patients and 84 patients who died from myocardial infarction (MI) was determined. Ñontrol group consisted of 1064 people. A significant (p <0,01) increase in leukocyte shift index of blood (LSI), the ratio of neutrophils and lymphocytes (NLymRI) and leukocyte intoxication index (LII) in patients with myocardial infarction compared to control, as well as in groups of patients with transmural end non-transmural MI were established. There were no differences in leukocyte integral indicators, depending on age and sex of patients. Recommended reference values ISLK, NLymRI and LII for use in clinical practice for the diagnosis of complicated MI.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):51-56
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The influence ofgenetic polymorphismsof CYP2C9 andVKORC1 on warfarin dosingin patientswith permanent formof atrial fibrillation
Rubanenko E.Y., Rubanenko E.Y.
Abstract
The article is devoted to assessing the influence of genetic polymorphisms of CYP2C9 and VKORC1 on warfarin dosing in patients with permanent form of atrial fibrillation. Studied were 100 patients with coronary heart disease and permanent form of atrial fibrillation, mean age 60,5±5,8 years. In patients with permanent form of atrial fibrillation genotypes CYP2C9*1/*3, TT and GG genotypes of VKORC1 are associated with low warfarin dose. Genotype CYP2C9*1/*3 increases the risk of bleeding complications during warfarin therapy.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):57-61
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Quality of life ofpatients with operatedtraumatic intracranialhematomas
Babochkin D.S., Babochkin D.S.
Abstract
The ñraniocereberal trauma is an actual problem of modern neurology and neurosurgery that is connected with high frequency and weight of consequences of this pathology. One of the types of heavy ñraniocereberal trauma is the traumatic intracranial hematoma. A research objective was studying of quality of life of patients in the remote period of surgical treatment traumatic covering hematomas. 120 patients ranging in age from 18 to 69 to terms from 6 months till 3 years after a trauma were examined. For definition of quality of life scale SF-36 was used. The conducted research has shown that that in the majority of supervision satisfactory indicators of quality of life are received. Dependence between quality of life of patients in the separated period and such factors, as localization, volume of hematomas and degree hypertensive-dislocation syndrome are revealed. The best indicators are recorded in group of patients with hematomas of small volume and with chronic subdural hematomas, and as operated in terms during 24 hours after a trauma.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):62-66
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Comparativeanalysis of the stomatologichealth of elderly peopleof the Samara region, beingin different social conditions
Balueva E.S., Baluyeva E.S.
Abstract
The article presents a comparative analysis of dental health of elderly people living in different social conditions in the Samara region. According to the results of epidemiological dental survey it was revealed that the dental health of elderly people living in institutions of social protection for all indicators were significantly worse than those who were living at home.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):67-69
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Features ofplatelet aggregation functionand microcirculation parametersin geriatric patientswith ischemic heart diseaseand gastroduodenalsystem pathology
Berdyashkina S.I., Berdyashkina S.I.
Abstract
The article considers the results of the study of platelet aggregation and functional changes in microcirculation parameters in groups tested. Researches have determined that the most significant changes in the state of aggregation and blood indicators of microcirculation were in patients with coronary artery disease, stable angina functional class II, first stage of heart failure, functional class I-II (NYHA), combined with duodenal ulcer in remission.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):70-72
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Clinicalfeatures of allergiccontact dermatitis
Bibarsova G.I., Bibarsova G.I.
Abstract
The article deals with the study of comparison subjective and objective signs of allergic contact dermatitis. The study included 30 allergic contact dermatitis patients The study found higher level of subjective ballets then objective in total index and in dichromate potassium, mixture aromatic materials, p-tert-butylphenol formaldehyde, carbamate mixture, pphenilendiamine and formaldehyde.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):73-76
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The epidemiologicalfeatures of multiplesclerosis in theUlyanovsk region
Greshnova I.V., Greshnova I.V.
Abstract
Analytical study of multiple sclerosis (MS) has been carried out with respect to international methodological criteria in the Ulyanovsk region; 127 pairs of MS patients were examined (81% female). The study shows that general MS risk factors for the taken population are: prolonged work with computer equipment, living near to construction materials production facilities under the age of 15, chronic herpes infection for all age categories, chronic bacterial infections (tonsillitis, sinusitis, abscesses) preceding to MS development, head injuries without loss of conscience under the age of 15 and prolonged contact with home animals for patients over the age of 15.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):77-83
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Type 2 diabetespharmaco-epidemiologyin the Samara region
Gudkova A.V., Gudkova A.V.
Abstract
The article presented data on the use of oral hypoglycemic agents in the treatment of type 2 diabetes in outpatient clinics of the Samara region.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):84-86
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Features of cellularcomponent of a system inflammationin patients withmoderate and mildform of ñhronicobstructive pulmonarydisease (COPD) in acute stage
Enikeev O.A., Enikeev O.A.
Abstract
In this article we cite data which demonstrate cellular component of a system inflammation in patients with moderate and mild stage of ñhronic obstructive pulmonary disease (COPD) in dynamics of hospital therapy during the exacerbation of the given disease. Control group consist from 20 conditionally healthy faces. The received results demonstrate that COPD exacerbations in patients with moderate and mild stage is characterized by strengthening phagocytic activity against decrease in number of such cells. Also at such patients activation Ò and B cells, against the raised level of the T-NK-cells that depict presence of chronic inflammation at patients already with mild stage is observed. At patients of moderate stage the exhaustion of NK-cells is observed. It speaks about easing of antiviral and antineoplastic immunity.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):87-90
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Hemostasis impairmentin patients with erythremia and multiplemyeloma in a combination with coronaryheart disease
Knyazeva N.S., Knyazeva N.S.
Abstract
On the basis of the Samara State Medical University Clinic 53 medical cases hematological malignancies (erythremia and multiple myeloma) were analyzed. Coronary heart disease (stable angina) occurred in accordingly 65% and 59% of cases. In the study of hemostasis (PTI, INR, ADP-platelet aggregation, collagen-platelet aggregation, platelet aggregation with MAP) a tendency to hypercoagulability in most patients was marked, mainly in patients with erythremia, the most specific test is the ADF-platelet aggregation. In view of revealed changes in these patients coagulation study and prevention of complications associated with the development of thrombosis should be enhanced.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):91-94
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Superficial facialelectromyography as a techniqueassessment of tuberculin diagnosis
Kozlova O.S., Kozlova O.S.
Abstract
For a choice of a technique of statement of optimal physiologically comfortable sample psychophysiological reactions of an organism of a child according to a superficial facial electromyography on Mantoux test reactions and prik-test has been studied. Performance of intradermal Mantoux test reactions with 2ÒÅ in children has taped the stressful reaction accompanied by negative emotional reaction. The offered technique prik-test has smaller irritating effect. It is low stress factor for children in comparison with a Mantoux reaction in case activation of parameters of a facial electromyogram in the first case occurs less on 67% on power and on 66% on amplitude. For carrying out of a mass tuberculin diagnosis the priktest is more optimal method.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):95-97
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Modern state ofthe problem of endothelialdysfunctionin COPD
Kuvaev V.S., Selikhova M.A., Kuvayev V.S., Selikhova M.A.
Abstract
This article is devoted to the review of current views concerning the development of endothelial dysfunction in COPD as one of the main pathogenetic factors of disease progression. In this article influence of cigarette smoke on the development of endothelial dysfunction are considered, the view concerning hypoxemia as a factor of the dysfunction of endothelium are revised, different methods investigation of microcirculation disorders and endothelial dysfunction in COPD are shown.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):98-102
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Comparativeanalysis of a postural tremor inpatients with the pyramidal anddyscoordination syndromes inpost-traumaticencephalopathy
Kutnikova T.A., Kutnikova T.A.
Abstract
An analysis of clinical and paraclinical indices obtained during the examination of 120 patients with post-traumatic encephalopathy. The features of postural tremor in the pyramidal and dyscoordination syndromes in a mild form with post-traumatic encephalopathy are revealed.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):103-109
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The changesin the peripheral blood ofHIV-infected patients with severecommunity-acquired pneumonia
Sabitova R.Y., Sabitova R.Y.
Abstract
The article investigates the changes in the peripheral blood of HIV-infected patients with severe community-acquired pneumonia. It was found that pneumonia in the late stages of HIV infection is characterized by anemia, leukopenia, a more pronounced shift to stab, decrease in the number of lymphocytes, monocytes, and increase of segmented neutrophils, higher levels of ESR. The study identified the relationship between the intensity of changes in the blood and the severity of pneumonia.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):110-114
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Effectiveness of ozonotherapyin the complex treatment ofchronic cystitisin women
Sizov K.A., Sizov K.A.
Abstract
We surveyed a group of patients with chronic cystitis. The aim was to study effectiveness of ozonotherapy in the complex treatment of such patients in the microcirculation of the bladder wall, and change the composition of the microflora of the lower urinary tract. The study involved 65 patients aged from 20 to 86. Patients were divided into three groups: the first group of patients (n=20) received complex conservative therapy, the patient of the second group (n=30) received, along with basic therapy intravesical instillation of ozonized solution, the third group of patients (n=15) was carried parenteral injection of ozonized saline. The use of ozonotherapy in the treatment of chronic cystitis in women has a pronounced bactericidal effect, causes an improvement of microcirculation in the bladder wall, leading to rapid disappearance of dysuric disorders.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):115-119
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Clinicoimmunologicalandmicrobiological aspectsof community-acquiredpneumoniain adults
Chigishchev A.P., Chigishchev A.P.
Abstract
The article is devoted to the analysis of the available domestic and foreign scientific literature and reflected modern understanding of ethiopathogenesis, clinical symptoms, immunological and microbiological aspects of community-acquired pneumonia in adults. In the work the epidemiological data and pathogenetic mechanisms of development of community-acquired pneumonia are resulted, diagnostic methods of disease are presented. The key moments of immunological reactance of an organism are reflected at the given disease. The data available in the literature on structure of pathogens of community-acquired pneumonia and modern indicators of antibiotic resistance in pathogenic strains are resulted.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):120-123
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Features of reproductivehealth of women - workersof mental work
Vlasova O.V., Vlasova O.V.
Abstract
The article analyzes the course of pregnancy and childbirth in women - workers of mental work. The influence of professional educators on the reproductive health of women during gestation, birth outcomes and neonatal state are shown. Complicated course of gestation: 2 times more likely to occur gestosis, intrauterine growth retardation are revealed. Deliveries are marked by fast term and the increase of surgical interventions in four times.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):124-127
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Realization predictionof neonatal infectionsin children of early age
Galakhova O.O., Galakhova O.O.
Abstract
The article presents literature data on the problem of babies' antenatal infection realization predictions mother's risk factors are discussed (mother's health peculiarities, gynecological anamnesis, present gestation and maternity development, placenta condition), as well as ways of infection carry-over to a fetus. Characteristics of fetus and infant condition favoring antenatal infection realization are also described. The necessity of complex approach to the antenatal infection realization risk estimation, which will allow decreasing infant mortality, is proved.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):128-134
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Diagnostic and prognostic value of serousand intercellularstatus in childrenand teenagers with varioustypes of juvenileidiopathic arthritis
Goryunov S.A., Pryanichnikova N.S., Goryunov S.A., Pryanichnikova N.S.
Abstract
For specification of diagnosis JIA and definition of the importance of pathogenetic changes research of parameters humor immunity, the most informative is shown at the given pathology, namely: a spectrum cytokines: TNF α, IL6, IL1β, IL4, a level spontaneous both stimulation lymphocytes and monocytes - TNF α. Value cytokines is determining in an inductive phase of the immune answer when they cause development of base reactions makrophages and antigen-specificaition cells: interaction of these cells with lymphocytes, activation and proliferation the last, in the certain degree - formation of cells - effector. At late stages of the immune answer, during realization - effector immunity functions the role cytokines becomes less significant. Level both stimulations lymphocytes and monocytes TNF α reflects activity of pathological process and can be used in forecasting outcomes juvenile idiopathic arthritis.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):135-140
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The microcirculation ofbulbar conjunctivain children livingin an area nearthe major highways
Zaynutdinova I.I., Sayfullina F.R., Dautov F.F., Zaynutdinova I.I., Saifullin F.R., Dautov F.F.
Abstract
We studied the microcirculation of bulbar conjunctiva of children living in an area near the major highways and children who live in areas remote from major highways. We have identified different dysfunction of microcirculation in children living near the major highways. In the control group microcirculation was changed slightly.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):141-143
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Features ofphysical development of the prematureinfants during the first year of life
Kalimullina A.R., Kalimullina A.R.
Abstract
Physical development indicators of 109 premature infants born between 29 and 37 weeks gestation have been studied. It has been shown that during the first year of life, body weight of premature infants is less than that of full term newborns of the same age. During the second half-year of life, according to the indicators of body length, head and chest circumference "moderately premature infants" (GA 32-36 6/7 weeks) catch up full term babies. Very premature infants (GA 29-31 6/7 weeks) demonstrate the lowest indicators of physical development combined with high growth paces of basic anthropometric parameters. We have determined succession of leveling indicators of physical development of premature infants: chest circumference, head circumference, length, body weight.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):144-151
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Diagnostics andtreatment features of bronchialasthma in children withbacterial contaminationof the upper respiratory tract
Korcheva E.G., Korcheva E.G.
Abstract
In order to optimize the treatment of children with torpid course of bronchial asthma the study was conducted, which confirmed the presence of certain features of bronchial asthma in children with colonization and inflammatory reaction of the mucous membranes of the upper respiratory tract. The data obtained substantiate the need for prompt diagnosis of microbial contamination and remediation of the upper respiratory tract infection (TTP) that will optimize treatment, reduce the duration of asthma exacerbations in children with bacterial colonization of the mucous TTP.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):151-158
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Optimization ofgestosis prophylactics by correctionsepidermal and transforming growthfactors in earlyterms of pregnancyin women withthe risk of interruptionof pregnancy
Malanina E.N., Malanina E.N.
Abstract
This study focuses on the clinical value of transforming growth factor-β (TGF-β2) and epidermal growth factor (EGF) in the maternal serum in earlier periods of pregnancy in order to set up groups at risk for the development of pregnancy complications.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):159-164
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Features ofage adaptation of women of thesecond period of a maturity
Ovsyanik O.A., Ovsyanik O.A.
Abstract
This report examines the result of women's age changing.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):165-170
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Pregnancy outcomesin women depending onvagina biocenosisin various termsof gestosis
Cherezova Y.M., Cherezova Y.M.
Abstract
It is clear that the idea of vaginal infection, as a purely isolated processes that do not involve reproductive disorders and complications of pregnancy, is gone. The suppression of colonization resistance of vaginal microflora contributes to the rising infection endometrium and fallopian tubes and development of infectious and inflammatory diseases of the pelvic organs, which can not affect the reproductive health of women planning pregnancy. The problem of violations of the biocenosis of the vagina during pregnancy in obstetric practice is relevant, as changer in vaginal microflora lead to complications during pregnancy, childbirth and the postpartum period, as well as the development of infections - inflammatory processes in the mother and fetus. We set out to examine violations of vaginal biocenosis in pregnant women and to analyze the outcome of pregnancy for both mother and fetus. We undertook a prospective study of 131 women. All women were examined according to accepted standards and in our developed algorithm in taking them on account of pregnancy.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):171-173
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Predictors ofcomplicationdevelopments after liver resections
Budyanskaya I.M., Budyanskaya I.M.
Abstract
Results of management of liver mosses in 159 patients treatment of 159 patients are presented. Routine blood analyses, duplex Doppler ultrasonography, reohepatography, intraoperative conditions were compared for predicting postoperative liver dysfunction and bile complications. We concluded that measurenant of the portal blood flow relocity, the volume of the liver resection and the intraoperative bluding are correlated with the development of the postoperative complications.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):174-177
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Assessment ofthe follow-ups of comminuteddiaphysial fractures of bonesof group «C»
Verkhovod A.Y., Verkhovod A.Y.
Abstract
The article describes typical features of segmental and fragmental tibial shaft fractures. The own rating scale of the follow-up treatment results is shown, considering features of fractures of group «C», is resulted. The results of operative treatment, depending on terms of osteosynthesis, are shown.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):178-181
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Modern scientificstate and prospective developmentin endoscopic surgery(literature review)
Kolsanov A.V., Yaremin B.I., Chaplygin S.S., Voronin A.S., Nazaryan A.K., Kolsanov A.V., Yaremin B.I., Chaplygin S.S., Voronin A.S., Nazaryan A.K.
Abstract
The author overviews new methods in endoscopic surgery and considers 3D-simulation for pre-surgical planning and intraoperative positioning. Due regard is given to features of working at da Vinci robot-aided surgery system, methods of surgery via special tools, clinical aspects of natural orifice transluminal endoscopic surgery (NOTES), and single-incision laparoscopic surgery (SILS).
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):182-186
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Possibilitieslow-intensive laser radiationapplication in preoperativepreparation of venous trophiculcers of lowerextremities
Kukol'nikova E.L., Kukolnikova E.L.
Abstract
The basis for the work is based on the results of treatment of 149 patients with chronic venous insufficiency of the lower extremities 6 class (the system of CEAP, 1994). In the comparative aspect of the efficiency of the method of preoperative preparation of venous trophic ulcers of the traditional way and with the use of low-intensity laser radiation with a simultaneous spray liquid medicines depending on the phase of the wound process. The obtained results show that the use of low-intensity laser radiation has significant advantages in comparison with traditional methods of preparation of venous trophic ulcers to surgical intervention, as it stimulates the reduction of terms of preoperative preparation of various in size and degree of changes of the surrounding tissue ulcers defects.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):187-191
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The use of medicalplasmapheresisand gravitationaltherapy in complex therapyof obliterating atherosclerosisof lower extremitiesarteries
Lopukhov E.S., Lopukhov E.S.
Abstract
Atherosclerotic chronic ischemia of lower extremities is not only characterized by availability of macro- and microcirculation abnormalities but also by imbalance of metabolic process. The use of medical plasmapheresis and gravitational therapy in complex therapy as opposed to traditional medicine makes it possible to improve the results of therapy and normalize the majority of examined results of antioxidant status, lipid spectrum and macrocirculation.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):192-194
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Correction method ofimmunometabolic disturbances in thelower extremities caused by obliteratingatherosclerosisof stage II
Lukashova A.V., Lukashova A.V.
Abstract
Chronic ischemia of the lower extremities caused by obliterating atherosclerosis is characterised by suppression of T-cell immunity, disbalance of indicators of humoral protection, components of complements´s system, activation of peroxide lipid oxidation, suppression of antioxidant protection. The use of autohemoozonotherapy in structure of complex conservative therapy, unlike traditional therapy, allows normalizing the majority of the investigated indicators of the immune and antioxidant status.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):195-197
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To a question aboutnerve trunksdamage duringthyroidectomy
Starostina A.A., Starostina A.A.
Abstract
The comparative analysis of treatment of 107 patients with various forms of toxic goiter was carried out. The direct results after operations from the position of trauma of bottom and returnable guttural nerves were studied. Visualization of the nerve trunks during thyroidectomy is the fundamental factor of trauma prophylactics. The basic moments of its providing are careful hemostasis and carefulness during interference on Berry's copula.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):198-200
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Modern surgery ofidiopathic macularhole with applicationof endovitrealdye «Brilliant Blue G»
Stebnev V.S., Stebnev V.S.
Abstract
In the article features and results of the surgical treatment idiopathic macular hole with application of modern microinvasive 23Gauge chromovitrectomy and endovitreal dye «Brilliant Blue G» are studied. Microinvasive 23Gauge chromovitrectomy with application of endovitreal dye «Brilliant Blue G» allows to achieve high anatomic and functional results in treatment of idiopathic macular hole in the early and remote period of supervision. Intraoperative and postoperative complications are studied with anatomic and functional results.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):201-204
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Application of plasma destructionof the bone tissue insurgical treatmentof patients with bonetumor-like diseases
Terskov A.Y., Ivanov V.V., Terskov A.Y., Ivanov V.V.
Abstract
During the experimental study we have estimated the bone tissue structural changes which take place after low-temperature plasma exposure. And we have also formed an estimate of outcomes after surgical treatment of patients with bone tumor-like diseases.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):205-206
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Assessment of thethe application of video-assistedmini-thoracotomy in patients withchest injuries complicated withpneumothorax and hemothorax inthe city clinical hospital
Titov A.N., Titov A.N.
Abstract
After the application of video-assisted mini-thoracotomy in 85 patients with chest injuries, aged from 15 to 92 the analysis has been done. The patients were divided into 3 groups, depending on the complication of the injury. 43 patients with posttraumatic pneumothorax, amounting to 50.6%, entered Group 1. 12 patients with posttraumatic hemothorax with suppressed or ongoing haemorrhage, amounting to 14,1%, entered Group 2. Group 3 enlisted 30 patients, amounting to 35,3%, being operated a week after they were taken into hospital. Mini-thoracotomy was applied to all patients with lateral incision of 6-8 cm long, 41% of patients had lengthened incisions up to 12cm because of technical difficulties. Thoracoscopy was carried out with standard equipment, rigid thorascope being used on 54 patients, amounting to 63,5%. 5 patients (5,9%) with severe concomitant injuries died. The effectiveness of video-assisted mini-thoracotomy for patients with chest injuries has been underlined.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):207-211
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Application ofinfra-red laser in complextreatment of the acuteand chronic cholangitisin patients after stricturesof hepaticocholedochus operations
Khunkuy I., Khunkuy I.
Abstract
They have generalized experience of treatment of 58 patients with traumas and strictures of hepaticocholedochus after operation after formation of biliodygastive anastomoses, including 6 patients with removable transpechenochnom anastomosis by Getts. All the patients after operations had exacerbation of cholangitis, but only 5,2% had lingering nature. When the treatment of acute and chronic cholangitis included infra-red laser exposure (0,63 mkm wave-length and power of 20 milliwatt) set up in drainage, it helped to arrest inflammation in patients of that category.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):212-215
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Surgical treatmentexperience of hemorrhage inlateral ventricles at acraniocereberal trauma in patientswith hypertension syndrome
Tsymbalyuk V.V., Krivoshchekov E.P., Naumova V.V., Tsymbalyuk V.V., Krivoshchekov E.P., Naumov V.V.
Abstract
In the article questions of surgical treatment of hemorrhage in lateral ventricles are considered at a craniocereberal trauma in patients with hypertension syndrome. By the directed transport of medicines with the help of auto-erythrocytes. The advantages of the given method over others in 30 patients are considered. The treatment and supervision of the patients with hemorrhage in lateral ventricles of brain with hypertension syndrome, by the directed transport of medicines are described in detail.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):216-219
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The advantage of the questionnairemethod while diseasestudying
Agaeva kyzy K.F., Shamyeva kyzy F.V., Agayeva K.F., Shamyeva F.V.
Abstract
The comparison of doctors' and teachers' morbidity data, received by different methods (by questionnaire and by collecting initial documents of public health care institutions of the state sector) was conducted. The preference of questionnaire method, which allowed getting more full information about morbidity, was shown. The differences of structure level of doctors' and teachers' morbidity considering both questionnaire data and facts of incidence were shown.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):220-223
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Outcome modelas a method of assessing the qualitymanagement of healthcare system
Sheshunova S.V., Sheshunova S.V.
Abstract
Outcome model as a method of assessing the quality management system of care includes indicators of performance, regulatory parameters and values of the scale for assessing performance. Creating a system of evaluation of health care institutions on the basis of the formation of the final results of models used for the analysis of all the organizations, including outpatient and inpatient. Using the principle of constructing a model of the final results of the activities of the hospital, in many settings in the Samara region developed system of quality assessment of each employee, the results of which are used for a differentiated approach to remuneration.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):224-228
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The experimental studyof postpirogen changes inthe cultivatedpine forest in theKrasnosamarskó area
Antipova A.V., Antipova A.V.
Abstract
The paper presents an experimental study of the charred tree-trunks after a forest fire in pine plantations in the Krasnosamarskу forest.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):229-235
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Tuberculosis sensitivityat active tuberculosis forms by theMantoux test 2TEand Diaskintest®
Akhmerova T.E., Akhmerova T.E.
Abstract
The effectiveness of the Diaskintest for detecting tuberculosis in 61 children and young people in the Children's Hospital of Samara city was studied. The most frequent forms of tuberculosis were intrathoracic lymph node tuberculosis (39, 3%) and infiltrative tuberculosis (27,9%). The Diaskintest® has shown its high diagnostic importance when dealing with local forms of active tuberculosis (88,5%). The negative test result by Diaskintest® does not exclude presence of tuberculosis. The Mantoux test remains important diagnostic test for detecting tuberculosis.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):235-238
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Diagnostic valueof serous leptin level and its correlationwith clinico-functionaland laboratorymarkers in atopicbronchial asthma incombination withobesity in teenagers
Vershinina V.V., Vershinina V.V.
Abstract
Diagnostic value of serous level of leptin and its correlation with clinico-functional and laboratory markers in atopic bronchial asthma in combination with obesity in teenagers was investigated. By means of laboratory methods, a bioipedansometry 38 patients with obesity and the positive anamnesis of an atopy were surveyed, ranging in age from12,38 to1,9 Descriptive and correlative analyses were carried out. From obtained diagnostic laboratory value, sensitivity and specific factor the following data were special IgE to a mix of pollen of trees of black-earth zone (AUROC ≥0,7), IgE to a mix of pollen of meadow herbs, IgE to a tick Dermatophag, IgE к Asperg, IgE total (AUROC >0,5), and eosinophiles and monocytes of peripheral blood (AUROC >0,5).
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):239-246
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Metabolites levelin blood and enzymes activity inthe liver at acute alcoholicintoxication in ratswith experimental diabetes
Zharkova N.V., Stel'makh A.Y., Medvedeva N.B., Zharkova N.V., Stelmakh A.Y., Medvedeva N.B.
Abstract
On the model of acute alcoholic intoxication at a singl dose 4 g/kg in rats is shown that in 6 hours in blood the level of free fat acids, urea is increased. In 24 hours concentration of glucose, lactate and urea is increased, the level of free fat acids decreases. Activity of glutamatdehydrogenasa and tirosinaminotransferasa in liver at acute alcoholic intoxication increases. In the rats with experimental diabetes (15 day) in 6 hours after an injection of ethanol in blood the level of glucose, urea, triglycerols is increased, the concentration of free amino acids, lactate is lowered. In this condition in liver of experimental animals activity of glutamatdehydrogenasa decreases and tirosinaminotransferasa increases. In 24 hours in blood concentration of triglycerols is lowered very much, the level of urea remains increased.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):247-250
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Features ofbiological propertiesand pathogenicityfactors of non-fermentingGram-negative bacteria,isolated from patients
Kondratenko O.V., Kondratenko O.V.
Abstract
The study of biological properties and factors of pathogenic strains of Pseudomonas aeruginosa, isolated from patients with cystic fibrosis are conducted. Revealed features of cultural properties, the presence of formation of pigment, hemolytic, phospholipase and proteolytic activity occur depending on the source selection. These data reveal the most significant biological and pathogenic features for identification of cultures.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):251-253
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Densitometryanalysis of barbiturates in theforensic chemical examination
Kormishin V.A., Kormishin V.A.
Abstract
In this article working out technique of the densitometric analysis and optimization of preliminary research in the chemical-toxicological analysis of barbiturates - phenobarbital, barbital, barbamyl is described.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):254-256
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The expression of genes NO-synthesisat a trauma of locomotorsystem
Makarenko M.S., Samarin K.A., Berezovskiy D.P., Kornienko I.V., Makarenko M.S., Samarin K.A., Berezovsky D.P., Korniyenko I.V.
Abstract
In the experiment with unthoroughbred male rats the expression of genes NO-synthesis and morphometric indicators of vessels at a trauma of locomotor system at a damage zone were studied. Duration of the experiment was 1 and 14 days. It is established that the expression of genes NOS1 and NOS3 was extremely low in all experimental groups. While authentic reduction of level of the expression of gene NOS2 in 2,4 times to control group was noted after 14 days after the trauma.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):257-260
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Humate magnesiuminfluence on excretory kidney functionin acute nephritic insufficiencymodeling
Men'shikh L.E., Menshikh L.E.
Abstract
In the work the action of humate of magnesium at defeat of gentamicine of kidneys is studied. Functional and pathomorphological research is conducted. It is established that the magnesium humate has nephroprotecting action, stimulates nephritic excretion waters, sodium, сreatinine, urea, reduces allocation by potassium and fiber kidneys.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):261-265
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Ethanol influenceon dehydrogenasae function
Nefedova N.S., Nefedova N.S.
Abstract
Ethanol makes activating impact on glyceraldehydphosphatdehydrogenasae, an alpha- glycerophosphatdehydrogenasae, lactatedehydrogenasae of haemolysates systems and also isolated homogeneous proteins at the expense of the direct and mediated action.
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):266-268
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Prognostic valueof gene of HLA-DRB1in chronic myeloid leukemia
Ovsyannikova E.G., Ovsyannikova E.G.
Abstract
In this research work we studied the HLA- DRB1 gene in patients with chronic myeloid leukemia (CML), who have been treated with Gleevec for 24 months. The study found that the markers of poor prognosis of CML, which predict failure to achieve a complete cytogenetic response after 24 months of Gleevec therapy are the specificities DRB1*14 (06); DRB1*11 (05); DRB1*12 (05). The markers of favorable prognosis of CML, which characterize the achievement of complete cytogenetic remission after 24 months of Gleevec therapy are DRB1*15 (02); DRB1*16 (02).
Aspirantskiy Vestnik Povolzhiya. 2012;12(1-2):269-272
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