New laser technology in diagnostics and low lip cancer therapy

Fluorescent diagnostics and photodynamic therapy in 45 patients with cancer of the lower lip using a photosensitizer Photosens, which was introduced in a dose of 0.5 mg / kg and 0.8 mg / kg. were held. In 24 hours after the administration of Photosense fluorescence the intensity in tumor cancer in the lower lip cancer patients increased dramatically and was 150.8 rel. u., diagnostic contrast ratio was 1.7. With increasing doses of the injectable preparation (from 0.5 to 0.8 mg / kg) fluorescence intensity in tumor lesions and in healthy mucosa was increased. While evaluating the overall effect of the treatment was reported in 69% of patients, a partial response was observed in 25% of patients and 6% of patients recorded stabilization. According to the results of the therapy there was a slight deviation from the norms of physiological indices studied the functional status of the liver and kidneys.

lower lip cancer, fluorescent diagnostics, photodynamic therapy, intensity of the fluorescence ratio of diagnostic contrast, photosensitizer «Photosens»