Email this article The treatment pathomorphism assessment of prostate cancer afterthe hormonal therapy
- Authors: Poletaeva SV1, Poletaeva SV1
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- Issue: Vol 12, No 5-6 (2012)
- Pages: 282-287
- Section: Articles
- URL: https://aspvestnik.ru/2410-3764/article/view/25685
- DOI: https://doi.org/10.17816/2072-2354.2012.0.5-6.282-287
- ID: 25685
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Abstract
For the purpose of studying treatment effects of neoadjuvant androgen deprivation in prostate cancer, histological material from 130 patients are examined. 30 patients had received hormonal treatment before radical prostatectomy. All patients were undergone TRUS-guided 12-cores biopsy. Histological, computer morphometry, immunohistochemical methods were used. Rate of (+) surgical margin in group with the hormonal treatment was 13%, in the control group - 17%. The response to androgen deprivation was variable, with areas of the cancer appearing unaffected. The important task is to identify the grade of treatment effects, because the therapy depends on it.
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