Severe osteoporosis against primary ovarian failure in triplet sisters

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Abstract

Abstract. During menopause period, the risk of osteoporosis and pathological fractures increases, especially with its immature or early onset. Both heredity and possible prenatal developmental disorders play a significant role in the development of these conditions, especially in children born from multiple pregnancies. This emphasizes the necessity for special attention to females from the risk groups for their timely referral to specialized professionals, prescription of treatment for osteoporosis and consideration of the possibility of using menopausal hormone therapy. The article describes clinical cases of severe osteoporosis that developed in triplet sisters in connection with immature or early menopause. The interest of the presented observations could be explained by fact of the lack of treatment and referral to an endocrinologist for patients with multiple pathological fractures in their anamnesis, which indicates insufficient awareness of these diseases among doctors of other specialties.

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About the authors

Svetlana V. Dora

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: doras2001@mail.ru
ORCID iD: 0000-0002-8249-6075
SPIN-code: 9845-0065

MD, Dr. Sci. (Medicine), professor

Russian Federation, Saint Petersburg

Yuri Sh. Khalimov

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: yushkha@gmail.com
ORCID iD: 0000-0002-7755-7275
SPIN-code: 7315-6746

MD, Dr. Sci. (Medicine), professor

Russian Federation, Saint Petersburg

Anna V. Lisker

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: a.lisker@mail.ru
ORCID iD: 0000-0003-4295-1202
SPIN-code: 3688-1505

MD, PhD (Medicine)

Russian Federation, Saint Petersburg

Zlata V. Shvets

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: shvetszlata31@gmail.com
ORCID iD: 0009-0007-9218-8133

clinical resident

Russian Federation, Saint Petersburg

Anna R. Volkova

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: volkovaa@mail.ru
ORCID iD: 0000-0002-5189-9365
SPIN-code: 4007-1288

MD, Dr. Sci. (Medicine), professor

Russian Federation, Saint Petersburg

Elena N. Ostroukhova

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: elenikos9@gmail.com
ORCID iD: 0000-0002-6542-7959
SPIN-code: 4103-7025

MD, PhD (Medicine), associate professor

Russian Federation, Saint Petersburg

Nargiz N. Mamedova

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Email: nsz90@mail.ru
ORCID iD: 0009-0002-2709-3641

MD

Russian Federation, Saint Petersburg

Alexandra B. Kolyabina

Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russia

Author for correspondence.
Email: kolyabinas@yandex.ru
ORCID iD: 0009-0003-3136-3509

student

Russian Federation, Saint Petersburg

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