A case of myxomatous degeneration of mitral valve leaflets complicated by chorda rupture
- Authors: Budnevsky A.V.1, Grechkin V.I.1, Kravchenko A.Y.1, Pertsev A.V.1
-
Affiliations:
- N.N. Burdenko Voronezh State Medical University
- Issue: Vol 12, No 3 (2026)
- Pages: 93-97
- Section: CLINICAL CASES
- Published: 21.05.2026
- URL: https://journals.eco-vector.com/2412-4036/article/view/707614
- DOI: https://doi.org/10.18565/therapy.2026.3.93-97
- ID: 707614
Cite item
Abstract
Acute mitral valve insufficiency is a common condition encountered by physicians of various specialties, including cardiologists, therapists, rheumatologists, and cardiac surgeons. The underlying causes of the disease are varied, and the severity of the condition, caused by the development of acute left ventricular failure, requires early diagnosis and urgent care, including surgical intervention. Current article presents a clinical case of myxomatous degeneration of the mitral valve leaflets in a 41-year-old patient, complicated by chordal rupture with the development of acute mitral regurgitation, which resulted in death.
About the authors
Andrey V. Budnevsky
N.N. Burdenko Voronezh State Medical University
Email: budnev@list.ru
ORCID iD: 0000-0002-1171-2746
SPIN-code: 7381-0612
Scopus Author ID: 6506507539
MD, Dr. Sci. (Medicine), Professor, Honored Inventor of the Russian Federation, Vice-Rector for Research and Innovation, Head of the Department of Faculty Therapy
Russian Federation, VoronezhVyacheslav I. Grechkin
N.N. Burdenko Voronezh State Medical University
Email: grechkin.vi@yandex.ru
ORCID iD: 0009-0002-6419-5401
SPIN-code: 2300-7098
MD, PhD (Medicine), Associate Professor of the Department of Faculty Therapy
Russian Federation, VoronezhAndrey Y. Kravchenko
N.N. Burdenko Voronezh State Medical University
Email: drkay@yandex.ru
ORCID iD: 0000-0003-0297-1735
SPIN-code: 8452-1318
Scopus Author ID: 56684358500
MD, Dr. Sci. (Medicine), Professor of the Department of Faculty Therapy
Russian Federation, VoronezhAlexander V. Pertsev
N.N. Burdenko Voronezh State Medical University
Author for correspondence.
Email: pertsev.vrn@yandex.ru
ORCID iD: 0000-0001-8984-1831
SPIN-code: 1432-9076
Scopus Author ID: 58096896200
MD, PhD (Medicine), Associate Professor of the Department of Faculty Therapy
Russian Federation, VoronezhReferences
- Андрияшкина Д.Ю., Демидова Н.А., Гевондян К.Р., Клименко А.А. Митральная регургитация: причины и механизмы развития, диагностика и исходы. Рациональная фармакотерапия в кардиологии. 2025;21(3):281–288. [Andriashkina DYu, Demidova NA, Gevondyan KR, Klimenko AA. Mitral regurgitation: Causes and mechanisms of development, diagnostics, and outcomes. Ratsional`naya farmakoterapiya v kardiologii = Rational Pharmacotherapy in Cardiology. 2025;21(3):281–288 (In Russ.)]. EDN: ZQZMBA. https://doi.org/10.20996/1819-6446-2025-3139
- Сукмарова З. Н., Овчинников Ю. В., Ларина О. М., Лепендин С. О., Афонина О. В., Громов А.И. Отрыв хорд митрального клапана у высокотренированных мужчин в ранние сроки после COVID-19. Серия клинических случаев. Спортивная медицина: наука и практика. 2022;12(1):77–85. [Sukmarova ZN, Ovchinnikov YuV, Larina OM, Lependin SO, Afonina OV, Gromov AI. Detachment of the mitral valve chords in highly trained men in the early stages after COVID-19. A series of clinical cases. Sportivnaya meditsina: nauka i praktika = Sports Medicine: Science and Practice. 2022;12(1):77–85 (In Russ.)]. EDN: PATVVO. https://doi.org/10.47529/2223-2524.2022.1.2
- Watanabe N. Acute mitral regurgitation. Heart. 2019;105(9):671–77. PMID: 30824479. https://doi.org/10.1136/heartjnl-2018-313373
- Сторожаков Г.И. Острая митральная недостаточность. Сердце: журнал для практикующих врачей. 2007;6(2):110–112. [Storozhakov GI. Acute mitral insufficiency. Serdtse: zhurnal dlya praktikuyushchikh vrachey = Russian Heart Journal. 2007;6(2):110–112 (In Russ.)]. EDN: ODSUOF.
- Ревишвили Г.А., Жбанов И.В., Шабалкин Б.В. Ишемическая митральная недостаточность: современные возможности диагностики и хирургического лечения. Вестник Национального медико-хирургического Центра им. Н.И. Пирогова. 2021;16(1):139–144. [Revishvili GA, Zhbanov IV, Shabalkin BV. Ischemic mitral insufficiency: Modern possibilities of diagnostics and surgical treatment. Vestnik Natsional`nogo mediko-khirurgicheskogo Tsentra im. N.I. Pirogova = Bulletin of Pirogov National Medical and Surgical Center. 2021;16(1):139–144 (In Russ.)]. EDN: CTYTMI. https://doi.org/10.25881/BPNMSC.2021.17.27.027
- Iung B, Baron G, Butchart EG, Delahaye F, Gohlke-Barwolf C, Levang OW et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on valvular heart disease. Eur Heart J. 2003;24(13):1231–43. PMID: 12831818. https://doi.org/10.1016/S0195-668X(03)00201-X
Supplementary files
