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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Therapy</journal-id><journal-title-group><journal-title xml:lang="en">Therapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапия</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2412-4036</issn><issn publication-format="electronic">2713-1823</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">276897</article-id><article-id pub-id-type="doi">10.18565/therapy.2022.10.124-129</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical case of mitral and tricuspid insufficiency in a patient with chronic rheumatic heart disease and arrhythmia by type of atrial fibrillation</article-title><trans-title-group xml:lang="ru"><trans-title>Митральная и трикуспидальная недостаточность у пациентки с хронической ревматической болезнью сердца и нарушением ритма сердца по типу фибрилляции предсердий</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kobzeva</surname><given-names>Natalia D.</given-names></name><name xml:lang="ru"><surname>Кобзева</surname><given-names>Наталия Дмитриевна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD in Medicine, associate professor of the Department of internal diseases No. 1</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры внутренних болезней № 1</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kadyan</surname><given-names>Eduard G.</given-names></name><name xml:lang="ru"><surname>Кадян</surname><given-names>Эдуард Грачяевич</given-names></name></name-alternatives><bio xml:lang="en"><p>cardiologist</p></bio><bio xml:lang="ru"><p>врач-кардиолог</p></bio><email>kadyaneduard@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nerusin</surname><given-names>Ivan I.</given-names></name><name xml:lang="ru"><surname>Нерусин</surname><given-names>Иван Иванович</given-names></name></name-alternatives><bio xml:lang="en"><p>student</p></bio><bio xml:lang="ru"><p>студент</p></bio><email>nerusin.med@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Saybel</surname><given-names>Maria D.</given-names></name><name xml:lang="ru"><surname>Сайбель</surname><given-names>Мария Дмитриевна</given-names></name></name-alternatives><bio xml:lang="en"><p>student</p></bio><bio xml:lang="ru"><p>студент</p></bio><email>marsaybel@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Oleinikova</surname><given-names>Victoria D.</given-names></name><name xml:lang="ru"><surname>Олейникова</surname><given-names>Виктория Дмитриевна</given-names></name></name-alternatives><bio xml:lang="en"><p>student</p></bio><bio xml:lang="ru"><p>студент</p></bio><email>victoria-ol@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Appakov</surname><given-names>German I.</given-names></name><name xml:lang="ru"><surname>Аппаков</surname><given-names>Герман Игоревич</given-names></name></name-alternatives><bio xml:lang="en"><p>student</p></bio><bio xml:lang="ru"><p>студент</p></bio><email>german.appakov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov State Medical University of the Ministry of Healthcare</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Rostov Regional Clinical Hospital</institution></aff><aff><institution xml:lang="ru">ГБУ РО «Ростовская областная клиническая больница»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2022</year></pub-date><volume>8</volume><issue>10</issue><issue-title xml:lang="en">VOL 8, NO10 (2022)</issue-title><issue-title xml:lang="ru">ТОМ 8, №10 (2022)</issue-title><fpage>124</fpage><lpage>129</lpage><history><date date-type="received" iso-8601-date="2023-02-22"><day>22</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО «Бионика Медиа»</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2412-4036/article/view/276897">https://journals.eco-vector.com/2412-4036/article/view/276897</self-uri><abstract xml:lang="en"><p>The article presents a clinical observation of a multimorbid patient who underwent mitral and tricuspid valve surgery, left atrium auricle implication and atrial septal defect suturing in conditions of artificial blood circulation. The features of approaches to the treatment of a patient with a multimorbid pathology, the features of rhythm disturbances in acquired heart defects and the frequency of occurrence of combinations of such pathologies are discussed.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлено клиническое наблюдение мультиморбидной пациентки, которой была выполнена пластика митрального и трикуспидального клапанов, пликация ушка левого предсердия и ушивание дефекта межпредсердной перегородки в условиях искусственного кровообращения. Обсуждаются подходы к лечению пациентки с мультиморбидной патологией, особенности нарушений ритма при приобретенных пороках сердца и частота встречаемости комбинаций таких патологий.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chronic rheumatic heart disease</kwd><kwd>acute rheumatic fever</kwd><kwd>valvular heart disease</kwd><kwd>acquired heart defects</kwd><kwd>mitral insufficiency</kwd><kwd>tricuspid insufficiency</kwd><kwd>valve repair</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хроническая ревматическая болезнь сердца</kwd><kwd>острая ревматическая лихорадка</kwd><kwd>клапанное поражение сердца</kwd><kwd>приобретенные пороки сердца</kwd><kwd>митральная недостаточность</kwd><kwd>трикуспидальная недостаточность</kwd><kwd>пластика клапанов</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Marijon E., Mirabel M., Celermajer D.S., Jouven X. Rheumatic heart disease. 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