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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Therapy</journal-id><journal-title-group><journal-title xml:lang="en">Therapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапия</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2412-4036</issn><issn publication-format="electronic">2713-1823</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">279350</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Evaluating processes of cardiac remodeling in the development of chronic thromboembolic pulmonary hypertension</article-title><trans-title-group xml:lang="ru"><trans-title>Оценка процессов ремоделирования сердца при формировании хронической тромбоэмболической легочной гипертензии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shemenkova</surname><given-names>Victoria S.</given-names></name><name xml:lang="ru"><surname>Шеменкова</surname><given-names>Виктория Сергеевна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD candidate of the acad. A.I. Nesterov; therapist</p></bio><bio xml:lang="ru"><p>аспирант кафедры факультетской терапии им. акад. А.И. Нестерова; врач-терапевт</p></bio><email>vshemenkova@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shostak</surname><given-names>Nadezhda A.</given-names></name><name xml:lang="ru"><surname>Шостак</surname><given-names>Надежда Александровна</given-names></name></name-alternatives><bio xml:lang="en"><p>MD., professor, head of the acad. A.I. Nesterov Chair of Intermediate Level Therapy</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой факультетской терапии им. акад. А.И. Нестерова</p></bio><email>shostakkaf@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Klimenko</surname><given-names>Alesya A.</given-names></name><name xml:lang="ru"><surname>Клименко</surname><given-names>Алеся Александровна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD., associate professor of the acad. A.I. Nesterov Chair of Intermediate Level Therapy</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры факультетской терапии им. акад. А.И. Нестерова</p></bio><email>shostakkaf@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bogdanova</surname><given-names>Aleksandra A.</given-names></name><name xml:lang="ru"><surname>Богданова</surname><given-names>Александра Андреевна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD, head of the Department of functional diagnostics</p></bio><bio xml:lang="ru"><p>к.м.н., зав. отделением функциональной диагностики</p></bio><email>doc.aabogdanova@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kotova</surname><given-names>Darja P.</given-names></name><name xml:lang="ru"><surname>Котова</surname><given-names>Дарья Павловна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD., head of the Department of therapy; associate professor of acad. A.I. Nesterov Chair of Intermediate Level Therapy</p></bio><bio xml:lang="ru"><p>доцент кафедры факультетской терапии им. акад. А.И. Нестерова; к.м.н., зав. терапевтическим отделением</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian National Research Medical University named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Clinical Hospital № 1 named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская клиническая больница № 1 им. Н.И. Пирогова» Департамента здравоохранения города Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2018</year></pub-date><issue>3</issue><issue-title xml:lang="en">NO3 (2018)</issue-title><issue-title xml:lang="ru">№3 (2018)</issue-title><fpage>108</fpage><lpage>112</lpage><history><date date-type="received" iso-8601-date="2023-02-24"><day>24</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, ООО «Бионика Медиа»</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2412-4036/article/view/279350">https://journals.eco-vector.com/2412-4036/article/view/279350</self-uri><abstract xml:lang="en"><p>The aim. To evaluate the processes of remodeling of the right and left heart in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Material and methods. The study included 30 patients who underwent in-patient examination and treatment at the State Clinical Hospital №1 named after N.I. Pirogov, Moscow, to confirm the diagnosis of CTEPH and the selection of drug therapy. For all patients, one expert performed an echocardiographic (EchoCG) study to evaluate the parameters of the right and left parts of the heart. Results. Statistically significant correlations between the severity of CTEPH flow and the structural and functional parameters of the right and left parts of the heart were obtained. Conclusions. The evaluation of structural and functional echocardiographic parameters of cardiac remodeling in patients with CTEPH was performed. Correlation links between severity of the disease course and echocardiographic data are revealed, which allows a simple, non-invasive method to conduct dynamic observation of patients and to identify prognostically unfavorable factors of CTEPH course.</p></abstract><trans-abstract xml:lang="ru"><p>Цель работы - оценить процессы ремоделирования правых и левых отделов сердца у пациентов с хронической тромбоэмболической легочной гипертензией (ХТЭЛГ). Материал и методы. В исследование включено 30 пациентов, которые проходили стационарное обследование и лечение в ГКБ № 1 им. Н.И. Пирогова г. Москвы для подтверждения диагноза ХТЭЛГ и подбора медикаментозной терапии. Всем пациентам одним экспертом выполнялось эхокардиографическое (ЭхоКГ) исследование для оценки параметров правых и левых отделов сердца. Результаты. Получены статистически значимые корреляционные связи между тяжестью течения ХТЭЛГ и структурно-функциональными параметрами правых и левых отделов сердца. Заключение. Проведена оценка структурно-функциональных эхокардиографических показателей ремоделирования сердца у пациентов с ХТЭЛГ. Выявлены корреляционные связи между тяжестью течения заболевания и эхокардиографическими данными, что позволяет простым, неинвазивным методом проводить динамическое наблюдение за больными и выявлять прогностически неблагоприятные факторы течения ХТЭЛГ.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chronic thromboembolic pulmonary hypertension</kwd><kwd>echocardiographic parameters for pulmonary hypertension</kwd><kwd>cardiac remodeling processes</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хроническая тромбоэмболическая легочная гипертензия</kwd><kwd>эхокардиографические показатели при легочной гипертензии</kwd><kwd>процессы ремоделирования сердца</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Клинические рекомендации по диагностике и лечению хронической тромбоэмболической легочной гипертензии. 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