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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Therapy</journal-id><journal-title-group><journal-title xml:lang="en">Therapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Терапия</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2412-4036</issn><issn publication-format="electronic">2713-1823</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">626161</article-id><article-id pub-id-type="doi">10.18565/therapy.2023.9.108-116</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Modern viewpoint at prediabetes: Prevalence, diagnostic criteria, risk groups, screening</article-title><trans-title-group xml:lang="ru"><trans-title>Современный взгляд на предиабет: встречаемость, критерии диагностики, группы риска, скрининг</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7825-5597</contrib-id><contrib-id contrib-id-type="spin">3674-9620</contrib-id><name-alternatives><name xml:lang="en"><surname>Larina</surname><given-names>Vera N.</given-names></name><name xml:lang="ru"><surname>Ларина</surname><given-names>Вера Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Professor, Head of the Department of Polyclinic Therapy of the Faculty of General Medicine</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой поликлинической терапии лечебного факультета</p></bio><email>larinav@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7922-3896</contrib-id><contrib-id contrib-id-type="spin">8731-5610</contrib-id><name-alternatives><name xml:lang="en"><surname>Lankin</surname><given-names>Anton O.</given-names></name><name xml:lang="ru"><surname>Ланкин</surname><given-names>Антон Олегович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Resident of the Department of Outpatient Therapy of the Faculty of General Medicine</p></bio><bio xml:lang="ru"><p>ординатор каф. поликлинической терапии лечебного факультета </p></bio><email>lankin99_99@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3177-3407</contrib-id><contrib-id contrib-id-type="spin">9394-2871</contrib-id><name-alternatives><name xml:lang="en"><surname>Larin</surname><given-names>Vladimir G.</given-names></name><name xml:lang="ru"><surname>Ларин</surname><given-names>Владимир Геннадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD in Medical Sciences, Associate Professor, Associate Professor of the Department of Polyclinic Therapy of the Faculty of General Medicine</p></bio><bio xml:lang="ru"><p>к.м.н., доцент, доцент кафедры поликлинической терапии лечебного факультета</p></bio><email>larinvladimir@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2196-6739</contrib-id><contrib-id contrib-id-type="spin">2329-0384</contrib-id><name-alternatives><name xml:lang="en"><surname>Golovko</surname><given-names>Milada G.</given-names></name><name xml:lang="ru"><surname>Головко</surname><given-names>Милада Геннадиевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD in Medical Sciences, Associate Professor, Associate Professor of the Department of Polyclinic Therapy of the Faculty of General Medicine</p></bio><bio xml:lang="ru"><p>к.м.н., доцент, доцент кафедры поликлинической терапии лечебного факультета </p></bio><email>larinav@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2023</year></pub-date><volume>9</volume><issue>9</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>108</fpage><lpage>116</lpage><history><date date-type="received" iso-8601-date="2024-01-28"><day>28</day><month>01</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-01-28"><day>28</day><month>01</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, ООО «Бионика Медиа»</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2412-4036/article/view/626161">https://journals.eco-vector.com/2412-4036/article/view/626161</self-uri><abstract xml:lang="en"><p>Prediabetes is an important problem of our time, as it is not only a metabolic condition associated with a high risk of type 2 diabetes mellitus developing, but also has a role of independent predictor of the development of cardiovascular diseases and other complications. Quite often diabetes it is proceeding asymptomatic, and therefore current review considers the risk factors associated with prediabetes, basing on which the primary care physician will be able to examine the relevant group of patients more specifically. Despite existing generally accepted criteria, diagnosing prediabetes remains to be a quite complicated task, since the world’s leading experts do not agree on the threshold values for this condition. Use of comprehensive screening and lower glycemic values may lead to earlier detection of prediabetes and slow its further progression.</p></abstract><trans-abstract xml:lang="ru"><p>Предиабет является важной проблемой современности, так как представляет собой не только метаболическое состояние, сопряженное с высоким риском развития сахарного диабета 2-го типа, но и выступает самостоятельным предиктором развития сердечно-сосудистых заболеваний и других осложнений. Довольно часто он протекает бессимптомно, в связи с чем в представленном обзоре рассматриваются факторы риска, ассоциированные с предиабетом, ориентируясь на которые врач первичного звена сможет более прицельно исследовать соответствующую группу пациентов. Несмотря на существующие общепринятые критерии, диагностика предиабета остается сложной задачей, поскольку у ведущих мировых экспертов нет единой точки зрения относительно пороговых значений этого состояния. Применение комплексного скрининга и более низкие значения гликемии могут способствовать более раннему выявлению предиабета и замедлению его дальнейшего прогрессирования.</p></trans-abstract><kwd-group xml:lang="en"><kwd>prediabetes</kwd><kwd>type 2 diabetes mellitus</kwd><kwd>risk factors for prediabetes</kwd><kwd>cardiovascular diseases</kwd><kwd>prevention</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>предиабет</kwd><kwd>сахарный диабет 2-го типа</kwd><kwd>факторы риска предиабета</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>профилактика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Marx N., Federici M., Schutt K. et al.; ESC Scientific Document Group. 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes. 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