PREVENTION OF STROKE AND SYSTEMIC EMBOLISM IN PATIENTS WITH ATRIAL FIBRILLATION: FOCUS ON APIXABAN


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Abstract

This review of the literature data is dedicated to the choice of an oral anticoagulant for the prevention of ischemic stroke and systemic embolism in patients with atrial fibrillation. Detailed results of real-world clinical practice studies comparing the efficacy and safety of various direct oral anticoagulants are presented. Special attention is paid to groups of patients with atrial fibrillation and obesity, elderly and frail patients, as well as atrial fibrillation and impaired renal function.

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About the authors

Valentin A. Kokorin

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: valentinkokorin@yahoo.com
Dr. med. habil., associate professor, professor of the Department of hospital therapy named after academician P.E. Lukomsky 117997, Moscow, 1 Ostrovityanova Str. Moscow

Olga I. Boeva

Central State Medical Academy of Department of Presidential Affairs

Dr. med. habil., associate professor, professor of the Department of therapy, cardiology and functional diagnostics with the course of nefrology 121359, Moscow, 19/1A Marshala Timoshenko Str

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