METABOLIC SYNDROME IN PATIENTS WITH GOUT AND ITS IMPACT ON THE RISK OF CARDIOVASCULAR DISEASES


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Abstract

The prevalence of metabolic syndrome (MS) and its individual components in patients with gout was studied. Total risk of cardiovascular disease (CVD) in this group of patients was evaluated. The study involved 86 patients, the study group comprised 56 patients with primary chronic gout and MS, the comparison group consisted of 30 volunteers with MS without gout or any other inflammatory process. All patients underwent assessment of total CVD risk according to the PROCAM and SCORE scales. At least 1 additional symptom of MS was diagnosed in aft examined patients. In 13 patients (23,21%) of the main group and 1 (3,33%) patient of the comparison group aft 5 additional signs were identified. In patients of the main group we often identified more than 3 additional signs of MS. Arterial hypertension was detected in patients with MS regardless of the presence of gout. Total risk of CVD in patients of the main group was refiabfy higher in comparison with the group with isolated MS (p<0,01 for SCORE and p<0,05 for PROCAM).

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About the authors

Irina Mikhailovna Marusenko

Petrozavodsk State University; Ministry of Health of the Republic of Karelia

Email: imarusenko@yandex.ru
MD, Professor; Professor of the Department of Hospital Therapy; Chief rheumatologist 185010, Petrozavodsk, 33 Lenin av

Irina Igorevna Polskaya

Petrozavodsk State University

Email: irina_polskaya82@mail.ru
PhD, Associate Professor of the Department of Hospital Therapy 185010, Petrozavodsk, 33 Lenin av

Tatiana Ivanovna Kulagina

Petrozavodsk State University

Email: tik141@mail.ru
PhD, Associate Professor of the Department of Hospital Therapy 185010, Petrozavodsk, 33 Lenin av

Nataliya Nikolaevana Vezikova

Petrozavodsk State University

Email: vezikov23@mail.ru
MD, Professor, Head of the Department of Hospital Therapy 185010, Petrozavodsk, 33 Lenin av

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