Current aspects of the clinical course and outcomes of stable coronary heart disease in patients in the Republic of Dagestan

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Abstract

Within the population with stable angina, depending on the initial clinical, functional and anatomical factors, the individual prognosis can vary significantly.

The aim: to study the influence of various factors at the clinical course and outcomes of stable angina for secondary preventive measures optimization in patients in the Republic of Dagestan.

Material and methods. A retrospective, observational, cohort study was performed in 85 patients hospitalized on a planned basis from 01/01/2015 to 12/31/2017 with diagnosis «CHD. Stable exertional angina pectoris» in Dagestan Center for Cardiology and Cardiovascular Surgery (DCC and CVS). To clarify the clinical course and outcomes of the disease, all patients with whom telephone contact was established and who were alive were invited to the DCC and CVS for re-examination.

Results. During the observation period, a positive dynamic in the development of stable coronary artery disease was fixed. A rather low mortality rate was observed (only 5 patients from 85). Also during the study, there was fixed a decrease in the frequency of detection of a clinic of stable angina pectoris, patients adapted to the target levels of systolic and diastolic blood pressure with medication, they had less dyslipidemia. At the same time, a negative tendency in indexes of total cholesterol level was observed, which occurred due to the extremely low adherence of patients to lipid-lowering therapy. In the study, progression of the stage of chronic heart failure was observed, more frequent development of atrial fibrillation, in addition, not for all patients who needed myocardial revascularization, it was actually done.

Conclusion. Improving compliance with the prescribed drug therapy, more active educational work concerning the necessity of myocardial revascularization among patients will help improve the clinical course and outcomes of stable coronary artery disease.

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About the authors

Suleiman N. Mammaev

Dagestan State Medical University of the Ministry of Healthcare of Russia

Email: hepar-sul-dag@mail.ru

md, professor, professor of the department of hospital therapy 

Russian Federation, 367000, Makhachkala, 47 Lyakhova Str.

Nabi U. Chamsutdinov

Dagestan State Medical University of the Ministry of Healthcare of Russia

Email: nauchdoc60@mail.ru

md, professor, head of the department of faculty therapy and occupational diseases

Russian Federation, 367032, Makhachkala, 60a Dzhambulatova Str.

Diana Z. Panahova

Dagestan State Medical University of the Ministry of Healthcare of Russia

Email: panaxova92@mail.ru

assistant at the department of faculty therapy and occupational diseases

Russian Federation, 367032, Makhachkala, 60a Dzhambulatova Str.

Osman A. Makhachev

Dagestan State Medical University of the Ministry of Healthcare of Russia

Author for correspondence.
Email: oamakhachev@mail.ru

md, professor, head of the department of cardiology and cardiovascular surgery 

Russian Federation, 367032, Makhachkala, 60a Dzhambulatova Str.

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Supplementary files

Supplementary Files
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1. JATS XML
2. Рис. 1. Кривая Каплана-Майера, характеризующая выживаемость исследованных пациентов со стабильной ишемической болезнью сердца (годы)

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3. Рис. 2. Кривая Каплана-Мейера, характеризующая выживаемость пациентов со стабильной ишемической болезнью сердца (мес)

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4. Рис. 3. Сравнение изменений систолического (САД) и диастолического (ДАД) артериального давления у исследованных пациентов на двух этапах наблюдения

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