Features of nutritional support in diseases of the bronchopulmonary system

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Abstract

The aim of the study was to research the efficacy, safety and tolerability of the specialized food product for dietary therapeutic and dietary preventive nutrition «Drink for detoxification LEOVIT» in the complex therapy of patients with diseases of the bronchopulmonary system, as well as to optimize ways to correct micronutrient deficiency. To assess clinical efficacy, safety and tolerability, the product was administered to patients with bronchopulmonary diseases (occupational bronchial asthma, COPD) in a 15-day course, 1 time per day during or after meals. To conduct research, two randomized groups of patients with diseases of the bronchopulmonary system were formed. The study have established that a specialized medical product improves the quality of life, which is manifested in a decrease in the frequency of asthma attacks, sneezing and coughing, as well as in improving mood and increasing vitality, reducing fatigue, normalizing sleep. The therapeutic product has pronounced anti-inflammatory properties, reduces the concentration of CRP by more than 22% and leukocyte markers of intoxication, in particular the Kalfa–Kalif index by 36,3%, the Ostrovsky index by 38,23%, the Krebs index by 41,6%, the PLR index by 30,7%. A 15-day intake of a dietary product reduces lipid and glucose toxicity, reducing cholesterol by 10,8%, low-density lipoprotein by 5,2%, triglycerides by 10% and glucose by 9,5%, reduces the level of total and indirect bilirubin. The authors recommend a specialized therapeutic product for inclusion in the complex therapy of patients with bronchopulmonary diseases to reduce body intoxication and increase the effectiveness of the therapy used.

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About the authors

Tatiana L. Pilat

Academician N.F. Izmerov Scientific Research Institute of Labour Medicine

Author for correspondence.
Email: tpilat@leovit.ru
ORCID iD: 0000-0002-5930-8849

md, leading researcher 

Russian Federation, 105275, Moscow, 31 Budennogo Avenue

Lyudmila P. Kuzmina

Academician N.F. Izmerov Scientific Research Institute of Labour Medicine; I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University)

Email: kuzmina@irioh.ru
ORCID iD: 0000-0003-3186-8024

phd in biological sciences, professor, deputy director for research work, professor of the department of occupational medicine, aviation, space and diving medicine

Russian Federation, 105275, Moscow, 31 Budennogo Avenue; г. Москва

Maria M. Kolyaskina

Academician N.F. Izmerov Scientific Research Institute of Labour Medicine; I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University)

Email: koliaskina.mm@irioh.ru
ORCID iD: 0000-0001-5356-1598

phd in medical sciences, senior researcher at the laboratory of biomedical research, lecturer at the department of labour medicine, aviation, space and diving medicine

Russian Federation, 105275, Moscow, 31 Budennogo Avenue; Moscow

Nana A. Anvarul

Academician N.F. Izmerov Scientific Research Institute of Labour Medicine

Email: anvarul@irioh.ru

phd in medical sciences, senior researcher at the clinical department of occupational and industrially caused diseases of the laboratory of biomedical research

Russian Federation, 105275, Moscow, 31 Budennogo Avenue

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