Diagnostic capabilities of the analysis of exhaled air biochemical composition in respiratory diseases

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Abstract

Respiratory diseases diagnostics is a complex task for modern medicine, especially when using traditional methods associated with invasiveness and risks for patients. Exhaled air analysis based on the study of volatile organic compounds offers a non-invasive, rapid and accurate approach for detecting diseases such as chronic obstructive pulmonary disease, asthma, lung cancer, pneumonia and COVID-19. The aim of the research is to evaluate the diagnostic capabilities of exhaled air biochemical analysis for detection of various respiratory pathologies and determine the key advantages and limitations of this method. Exhaled air analysis is a promising diagnostic tool due to its non-invasiveness, high sensitivity and the possibility of repeated use. Despite the need for standardization of the method, its use has significant potential for improving the diagnosis and monitoring of respiratory diseases in clinical practice.

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About the authors

Anna V. Teteneva

Siberian State Medical University; Primary Healthcare Unit No. 2

Author for correspondence.
Email: anna.dubodelova@mail.ru
ORCID iD: 0000-0002-4323-2798
SPIN-code: 9472-4472
Scopus Author ID: 57214109808

MD, Dr. Sci. (Medicine), Professor of the Department of Internal Disease Propaedeutics with a Course in Therapy of the Faculty of Pediatrics; Deputy Chief Physician for Clinical and Expertise Work

Russian Federation, 2, Moskovsky Tract St., Tomsk, 634050; 3, Béla Kun Str., Tomsk, 634040

Inna D. Bespalova

Siberian State Medical University

Email: bespalova.id@ssmu.ru
ORCID iD: 0000-0002-4513-6329
SPIN-code: 6852-6200
Scopus Author ID: 55820749900

MD, Dr. Sci. (Medicine), Head and Professor of the Department of Internal Disease Propaedeutics with a Course in Therapy of the Faculty of Pediatrics

Russian Federation, 2, Moskovsky Tract St., Tomsk, 634050

Nikolay D. Yarovoy

Siberian State Medical University; Primary Healthcare Unit No. 2

Email: koly-yarovoy@yandex.ru
ORCID iD: 0000-0003-3619-6095
SPIN-code: 1707-4330

Resident of the Department of Biochemistry and Molecular Biology with a Course of Clinical Laboratory Diagnostics; Physician-Statistician

Russian Federation, 2, Moskovsky Tract St., Tomsk, 634050; 3, Béla Kun Str., Tomsk, 634040

Vladimir I. Chernov

Tomsk National Research Medical Center of the Russian Academy of Sciences

Email: achernov@tnimc.ru
ORCID iD: 0000-0001-8753-7916

MD, Dr. Sci. (Medicine), Professor, Corresponding Member of the RAS, Deputy Director for Research and Innovation Work, Head of the Department of Radionuclide Therapy and Diagnostics of the Research Institute of Oncology

Russian Federation, 5, Kooperativny Lane, Tomsk, 634009

Viktor I. Sachkov

National Research Tomsk State University

Email: Vicsachkov@outlook.com
ORCID iD: 0000-0001-7866-274X

Dr. Sci. (Chemistry), Associate Professor, Head of the Department of Chemical Technologies, Head of the Innovation and Technology Center of the Siberian Physics and Technology Institute

Russian Federation, 36, Lenin Ave., Tomsk, 634050

Tatiana V. Sorokina

Siberian State Medical University

Email: gbsmp.sorokinatatyana@mail.ru
ORCID iD: 0000-0002-6264-4632

MD, Head of the Therapeutic Clinic – Therapist

Russian Federation, 2, Moskovsky Tract St., Tomsk, 634050

Sofia V. Nesterovich

Siberian State Medical University

Email: nesterovich.sv@ssmu.ru
ORCID iD: 0000-0003-2098-2964

MD, PhD (Medicine), Chief Physician

Russian Federation, 2, Moskovsky Tract St., Tomsk, 634050

Denis I. Radionov

Minusinsk Interdistrict Hospital

Email: radionovdenis12@gmail.ru
ORCID iD: 0009-0004-2863-2736

MD, Therapist

Russian Federation, 2a, Botanicheskaya St., Minusinsk, 662606

Ekaterina V. Radionova

Minusinsk Interdistrict Hospital

Email: Opoldnik@yandex.ru
ORCID iD: 0000-0002-0696-2951

MD, Therapist

Russian Federation, 2a, Botanicheskaya St., Minusinsk, 662606

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