The importance of a multifactorial approach in the treatment of type 2 diabetes mellitus: clinical cases


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Аннотация

Due to the widespread and rapid growth of the disease, the development of complications, premature disability and high mortality of patients, type 2 diabetes mellitus (DM 2) remains the important medical and social problem. The increase in the number of patients with diabetes mellitus is primarily determined by patients with DM 2, especially the elderly. Despite the variety of medications in the doctor's arsenal, the problem of choosing optimal schemes of hypoglycemic therapy is still relevant. At the same time, next to the choice of medications for the treatment of DM 2, lifestyle modification, adherence to therapy and control of the disease on the part of the patient is of importance. In the clinical cases cited in the article, a comparative characteristic of the disease dynamics of two patients with DM 2, with a complicated course, who are on various hypoglycemic therapy, is presented. The example focuses on the influence of risk factors on the prognosis and course of the disease, as well as the choice of a treatment strategy aimed at the key processes of development and progression of diabetes mellitus.

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Авторлар туралы

Kristina Podorozhnyuk

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: kristina.podorozhnyuk1991@mail.ru
resident of the Department of endocrinology of the Faculty of general medicine

Daria Skuridina

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: shurpesha@mail.ru
assistant at the Department of endocrinology of the Faculty of general medicine

Әдебиет тізімі

  1. Мкртумян А.М. Многофакторный подход к управлению сахарным диабетом 2 типа: фокус на препараты инкретинового ряда. Эффективная фармакотерапия. 2021; 17(40): 48-50. [Mkrtumyan A.M. Multifactorial approach to the management of diabetes mellitus type 2: focus on incretin-type drugs. Effektivnaya farmakoterapiya = Effective Pharmacotherapy. 2021; 17(40): 48-50 (In Russ.)]. EDN: RIPIJQ.
  2. Халимов Ю.Ш., Рудакова А.В. Оценка эффективности затрат на интенсивную терапию сахарного диабета 2-го типа (по данным исследования Steno-2). Сахарный диабет. 2011; 14(2): 116-120. [Khalimov Yu.Sh., Rudakova A.V. A cost-effectiveness analysis of intensive therapy of type 2 diabetes mellitus (results of Steno-2 study). Sakharny diabet = Diabetes Mellitus. 2011; 14(2): 116-120 (In Russ.)]. https://dx.doi.org/10.14341/2072-0351-5647. EDN: NKREDS.
  3. Дедов И.И., Шестакова М.В. Феномен «метаболической памяти» в прогнозировании риска развития сосудистых осложнений при сахарном диабете. Терапевтический архив. 2015; 87(10): 4-10. [Dedov I.I., Shestakova M.V. The metabolic memory phenomenon in predicting a risk for vascular complications in diabetes mellitus. Terapevticheskiy arkhiv = Therapeutic Archive. 2015; 87(10): 4-10 (In Russ.)]. https://dx.doi.org/10.17116/terarkh201587104-10. EDN: TFBZFD.

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