System analysis of endothelium dysfunction in pat with arterial hypertension, the inhabitants of highlands


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The paper presents the results of a system analysis of the functional state of the endothelium in healthy individuals and patients with arterial hypertension (AH), the inhabitants of the highlands, conducted on the basis of structural and morphological analysis of the main systems of the endothelium on the concentration of nitric oxide (NO) and its metabolites in the blood of nitrite (NO- 2) and nitrates (NO- 3), heart rate variability (HRV), the morphological structure of the myocardium and hemodynamic parameters. The mountain Prielbrusya surveyed 195 indigenous people - 50 healthy persons and patients with arterial hypertension (AH) 145 different degree. All. patients, but clinical, instrumental and biochemical research. The obtained results are systematized with the help of multiple regression equations and factor analysis. The dependences of the absolute and relative values of indicators and indices of HRV, gemodynamics, the morphological structure of the myocardium on the concentration of NO in the blood and the level of mean arterial pressure (MAP). Systematic analysis of the most important factors that allowed to show the contribution of the most important factors in the variation of resultant signs and assess the results of actions of their set objectives.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Mariam Kurdanova

Center for medical and environmental research, branch of State research center of Russian Federation - Institute of biomedical problems of RAS

Email: maryamk@mail.ru
PhD, leading researcher of the Department of clinical medicine and physiology, academic secretary

Anatoliy Martynov

A.I. Yevdokimov Moscow state university of medicine and dentistry

Email: mailbox@rnmot.ru
academician of Russian academy of sciences, MD, professor, president of Russian scientific medical society of internal medicine, professor of the Department of hospital therapy № 1

Iliyas Beslaneev

Center for medical and environmental research, branch of State research center of Russian Federation - Institute of biomedical problems of RAS

Email: ibisl@yandex.ru
PhD, leading researcher of the Department of high-altitude physiology and pathology

Luiza Batyrbekova

Center for medical and environmental research, branch of State research center of Russian Federation - Institute of biomedical problems of RAS

PhD, leading researcher, head of the Department of clinical medicine and physiology, academic secretary

Huseyn Kurdanov

Center for medical and environmental research, branch of State research center of Russian Federation - Institute of biomedical problems of RAS

MD, professor, head

Әдебиет тізімі

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