Metabolic markers of cerebrovascular pathology

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Аннотация

Aspects of correlation between cerebrovascular diseases (CVD) and metabolic disorders that are extremely actual due to the pandemic increase of the incidence of obesity (OB) and diabetes mellitus (DM) are discussed in the article. The number of brain strokes in the world and problems of associated medical and social consequences are constantly increasing. The problem of effective primary prevention of CVD has not been solved, which determines the need for stratification of high-risk individuals and early diagnosis of vascular cerebral pathology. Influence of a wide range of biologically active molecules associated with obesity and diabetes mellitus at the development of cerebral vascular pathology has been shown; pro-inflammatory, pro-atherogenic and pro-thrombogenic effects of metabolic disorders have been fixed. Determining a biomarker panel of cerebrometabolic pathology may become a significant milestone in the development of strategies for the prevention and treatment of cerebrovascular diseases.

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Авторлар туралы

Marine Tanashyan

Scientific Center of Neurology

Хат алмасуға жауапты Автор.
Email: mtanashyan@neurology.ru
ORCID iD: 0000-0002-5883-8119
SPIN-код: 7191-1163
Scopus Author ID: 6506228066
ResearcherId: F-8483-2014

MD, Dr. Sci. (Medicine), professor, corresponding member of RAS, deputy director for scientific work, head of the 1st Neurological Department

Ресей, 125367, Moscow, 80 Volokolamskoe Highway

Ksenia Antonova

Scientific Center of Neurology

Email: kseniya.antonova@mail.ru
ORCID iD: 0000-0003-2373-2231
SPIN-код: 7737-4712
Scopus Author ID: 7004672742
ResearcherId: J-9971-2016

MD, Dr. Sci. (Medicine), leading researcher, endocrinologist

Ресей, 125367, Moscow, 80 Volokolamskoe Highway

Nikita Spryshkov

Scientific Center of Neurology

Email: nikita_spryshkov@mail.ru
ORCID iD: 0000-0002-2934-5462
SPIN-код: 4604-7589

MD, 1st year postgraduate student, neurologist

Ресей, 125367, Moscow, 80 Volokolamskoe Highway

Anastasia Panina

Scientific Center of Neurology

Email: nastena.panina.98@mail.ru
ORCID iD: 0000-0002-8652-2947

MD, 1st year postgraduate student, neurologist

Ресей, 125367, Moscow, 80 Volokolamskoe Highway

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