COVID-19/HlV co-infection: characteristics of patients in the Moscow megalopolis


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Resumo

The aim of the study is to study the prevalence of COVID-19 among HIV-infected patients in Moscow region and the influence of COVID-19 epidemy at the provision of specialized medical care to patients living with HIV. Materials and methods. For the period of 2020-21 were analyzed the data of 158 patients aged 20-71 who were observed at the Moscow city center for the prevention and control of AIDS of the infectious clinical hospital No. 2 (ICH No. 2 of Moscow Healthcare Department) and who had a combined pathology of COVID-19/HIV infection. In addition to standard examination methods, all participants underwent nasopharyngeal swabs for testing for coronavirus (polymerase chain reaction), indicators of immune status (CD4 + lymphocytes, CD8 + lymphocytes), HIV viral load were determined. If COVID-19 was suspected, a chest computed tomography (CT scan) was performed. Results and conclusion. The mutual influence of SARS-CoV-2 infection and HIV was examined in terms of age, sex, stage of HIV infection, immune status, HIV viremia, conditions of specialized medical care performance, use of antiretroviral therapy (ART), the severity of COVID-19 clinical course and the prognosis of the disease. Indicators of immune status, HIV viremia, ART intake, stage of HIV infection, as well as the location of receiving specialized medical care (inpatient / outpatient treatment) had a correlation with the severity of COVID-19/HIV coinfection and had a prognostic value. Decompensation of the clinical course of HIV infection with a detectable HIV viral load and a decrease in CD4 + <500 pl-1 in the blood, the absence of ART and follow-up by a specialist at the Moscow city center for prevention and control of AIDS in most cases (89%) caused a severe clinical course of COVID-19.

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Sobre autores

Alexey Mazus

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: aids@spid.ru
MD, Honored healthcare worker of the Russian Federation, head 105275, Moscow, 15 8th Sokolinoy gory Str

Margarita Nagibina

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: infector03@gmail.com
MD, professor, infectious disease physician of the HIV prevention Department 105275, Moscow, 15 8th Sokolinoy gory Str

Timur Bessarab

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: bessarab@spid.ru
PhD, head of the HIV prevention Department 105275, Moscow, 15 8th Sokolinoy gory Str

Elena Tsyganova

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: tsyganovaelena@yandex.ru
PhD, head of the scientific and clinical Department 105275, Moscow, 15 8th Sokolinoy gory Str

Natalya Litvinova

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: nlitvinova25@mail.ru
infectious disease doctor of the polyclinic Department 105275, Moscow, 15 8th Sokolinoy gory Str

Elena Belova

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: elena_belova@inbox.ru
PhD, infectious disease doctor, of HIV prevention Department 105275, Moscow, 15 8th Sokolinoy gory Str

Dinara Nabiullina

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: dinara.nab@gmail.com
methodologist of the HIV prevention Department 105275, Moscow, 15 8th Sokolinoy gory Str

Madina Kesaeva

Moscow City Center for the Prevention and Control of AIDS of the Department of Healthcare of Moscow

Email: kesaeva-m@mail.ru
PhD, infectious disease doctor of the HIV prevention Department 105275, Moscow, 15 8th Sokolinoy gory Str

Bibliografia

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