Paraneoplastic thromboendocarditis: Analysis of three cases in patients with gastric tumor lesion

Capa

Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Acesso é pago ou somente para assinantes

Resumo

Observations of three cases of one of complications of tumor processes – non-bacterial (non-infectious, aseptic) thrombotic endocarditis as paraneoplastic process in patients with adenocarcinoma and gastrointestinal stromal tumor – GIST of stomach wall are presented. Clinical manifestations of autoimmune and coagulopathic syndromes associated with tumors and endocarditis are discussed.

Texto integral

Acesso é fechado

Sobre autores

Alexander Yagoda

Stavropol State Medical University of the Ministry of Healthcare of Russia

Autor responsável pela correspondência
Email: alexander.yagoda@gmail.com
ORCID ID: 0000-0002-5727-1640

MD, Professor, Head of the Department of Hospital Therapy

Rússia, Stavropol

Natalya Gladkikh

Stavropol State Medical University of the Ministry of Healthcare of Russia

Email: ngladkih@mail.ru
ORCID ID: 0000-0003-4510-3604

MD, Professor, Professor of the Department of Hospital Therapy

Rússia, Stavropol

Pavel Koroy

Stavropol State Medical University of the Ministry of Healthcare of Russia

Email: Paule75@yandex.ru
ORCID ID: 0000-0001-6392-8461

MD, Professor, Professor of the Department of Hospital Therapy

Rússia, Stavropol

Anna Rybas

Stavropol State Medical University of the Ministry of Healthcare of Russia

Email: rybasdoc@mail.ru
ORCID ID: 0000-0001-5360-0913

PhD in Medical Sciences, Associate Professor of the Department of Hospital Therapy

Rússia, Stavropol

Bibliografia

  1. Гогин Е.Е., Нешитов С.П., Чуванов М.В., Скалозуб О.И. Сложность распознавания паранеопластических синдромов. Терапевтический архив. 2008; 80(4): 73–76. [Gogin E.E., Neshitov S.P., Chuvanov M.V., Skalozub O.I. Difficulty of recognizing paraneoplastic syndromes. Terapevticheskiy arkhiv = Therapeutic Archive. 2008; 80(4): 73–76 (In Russ.)]. EDN: JTDHMJ.
  2. Акимов В.Г. Роль дерматолога в ранней диагностике онкологических заболеваний. Consilium Medicum. 2015; 17(12): 68–72. [Akimov V.G. Dermatologist’s role in the early diagnosis of oncologic diseases. Consilium Medicum. 2015; 17(12): 68–72 (In Russ.)]. EDN: VIMUUN.
  3. Yoo J., Choi J.K., Kim Y.D. et al. Outcome of stroke patients with cancer and nonbacterial thrombotic endocarditis. Stroke. 2020; 22(2): 245–53. https://dx.doi.org/10.5853/jos.2020.00619.
  4. Gupta S., Bravo M.C., Heiman M. et al. Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX: C deficiency vs. controls. Thromb Res. 2019; 182: 43–50. https://dx.doi.org/10.1016/j.thromres.2019.07.020.
  5. Le Bot A., Jego P., Donal E. et al. Non-infective endocarditis. Rev Med Interne. 2018; 39(10): 782–91. https://dx.doi.org/10.1016/j.revmed.2018.03.020.
  6. Dipasco P.J., Misra S., Koniaris L.G., Moffat F.L. Jr. Thrombophilic state in cancer, part 1: Biology, incidence, andriskfactors. J Surg Oncol. 2011; 104(3): 316–22. https://dx.doi.org/10.1002/jso.21925.
  7. Терентьев В.П., Батюшин М.М., Дерижанова И.С., Гасанов М.З. Паранеопластический синдром. Ростов-на-Дону. 2010; 157 с. [Terentyev V.P., Batyushin M.M., Derizhanova I.S., Hasanov M.Z. Paraneoplastic syndrome. Rostov-on-Don. 2010; 157 рp. (In Russ.)].
  8. Bedikian A., Vaidviesco M., Luna M. et al. Nonbacterial thrombotic endocarditis in cancer patients with or without concomitant disseminated intravascular coagulation. Med Pediatr Oncol. 1978; 4(2): 149–57. https://dx.doi.org/10.1002/mpo.2950040211.
  9. Ягода А.В., Гладких Н.Н. Эндокард и клапаны сердца при системных ревматических болезнях. Рецензенты: Левитан Б.Н., Елисеева Л.Н. Ставрополь: Ставропольский государственный медицинский университет. 2021; 296 c. [Yagoda A.V., Gladkikh N.N. Endocardium and heart valves in systemic rheumatic diseases. Reviewers: Levitan B.N., Eliseeva L.N. Stavropol: Stavropol State Medical University. 2021; 296 рp. (In Russ.)]. ISBN: 978-5-89822-717-3. EDN: TZMWNC.
  10. Комаров В.Т., Татарченко И.П. Дифференциальная диагностика инфекционного и неинфекционных тромботических эндокардитов. Клиническая медицина. 2001; 79(10): 17–21. [Komarov V.T., Tatarchenko I.P. Differential diagnosis of infectious and non-infectious thrombotic endocarditis. Klinicheskaya meditsina = Clinical Medicine. 2001; 79(10): 17–21 (In Russ.)].
  11. Edoute Y., Haim N., Rinkevich D. et al. Cardiac valvular vegetations in cancer patients: Prospective echocardiographic study of 200 patients. Am J Med. 1997; 102(3): 252–58. https://dx.doi.org/10.1016/S0002-9343(96)00457-3.
  12. Takeshita S., Ogata T., Mera Y. et al. Multiple thrombi in the heart in trousseau syndrome caused by pancreatic carcinoma. J Stroke Cerebrovasc Dis. 2018; 27(5): e75–77. https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.12.005.
  13. Ягода А.В., Цветков В.С., Титоренко В.В. Два случая миксомы левого предсердия с артериальными и венозными тромбозами. Клиническая медицина. 1984; 62(11): 114–117. [Yagoda A.V., Tsvetkov V.S., Titarenko V.V. Two cases of left atrial myxoma with arterial and venous thrombosis. Klinicheskaya meditsina = Clinical Medicine. 1984; 62(11): 114–117 (In Russ.)].
  14. Heija M., Raderer M., Zielinski C. Inhibition of metastasis by anticoagulants. J Natl Cancer Inst. 1999; 91(1): 22–36. https://dx.doi.org/10.1093/jnci/91.1.22.
  15. Смолякова Р.М., Машевский А.А., Мавричев С.А. с соавт. Молекулярно-генетические аспекты патогенеза венозных тромбозов и тромбоэмболии легочной артерии. Онкологический журнал. 2007; 1(2): 54–62. [Smolyakova R.M., Mashevsky A.A., Mavrichev S.A. et al. Molecular and genetic aspects of the pathogenesis of venous thrombosis and pulmonary embolism. Onkologicheskiy zhurnal = Journal of Oncology. 2007; 1(2): 54–62 (In Russ.)]. EDN: RPUPYD.
  16. Scozzafava J., Hussain M.S., Ahmed S.N., Khan K. Reccurent strokes in a 46-year-old woman: Rapidly progressive nonbacterial thrombotic endocarditis. Can Med Assoc J. 2006; 175(9): 1055–56. https://dx.doi.org/10.1503/cmaj.060499.
  17. El-Shami K., Griffits E., Streif M. Nonbacterial thrombotic endocarditis in cancer patients: Pathogenesis, diagnosis, and treatment. Oncologist. 2007; 12(5): 518–23. https://dx.doi.org/10.1634/theoncologist.12-5-518.
  18. Zingone A., Kuehl W.M. Pathogenesis of monoclonal gammopathy of undetermined significance (MGUS) and progression to multiple myeloma. Semin Hematol. 2011; 48(1): 4–12. https://dx.doi.org/10.1053/j.seminhematol.2010.11.003.
  19. Клиническая онкогематология. Руководство для врачей. Под ред. М.А. Волковой. М.: Медицина. 2001; 576 с. [Clinical oncohematology. Guide for doctors. Ed. by Volkova M.A. Moscow: Meditsina. 2001; 576 рp. (In Russ.)]. ISBN: 5-225-04580-4.
  20. Sallah S., Husain A., Wan J. et al. The risk of venous thromboembolic disease in patients with monoclonal gammopathy of undetermined significance. Ann Oncology. 2004; 15(10): 1490–94. https://dx.doi.org/10.1093/annonc/mdh385.
  21. Srkalovic G., Cameron M.G., Rybicki L. et al. Monoclonal gammopathy of undetermined significance and multiple myeloma are associated with an increased incidence of venothromboembolic disease. Cancer. 2004; 101(3): 558–66. https://dx.doi.org/10.1002/cncr.20405.
  22. Eby C.S. Bleeding and thrombosis risks in plasma cell dyscrasias. Hematol Am Soc Hematol Educ Program. 2007: 158–64. https://dx.doi.org/10.1182/asheducation-2007.1.158.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML
Baixar
2. Fig. 1. Patient S.: echocardiography, parasternal position, long axis of the left ventricle, thickening of the mitral valve leaflets, mobile formations on the leaflets - organized vegetations

Baixar (1MB)
Metadados
3. Fig. 2. Patient P.: echocardiography, apical 4-chamber position, small organized vegetations on the mitral valve leaflets, calcinosis of the base of the posterior leaflet

Baixar (2MB)
Metadados
4. Fig. 3. Patient K.: gastric wall stromal tumor (GIST). Hematoxylin and eosin staining x200

Baixar (2MB)
Metadados

Declaração de direitos autorais © Bionika Media, 2023

Este site utiliza cookies

Ao continuar usando nosso site, você concorda com o procedimento de cookies que mantêm o site funcionando normalmente.

Informação sobre cookies