Peculiarities of food sensitization in patients having bronchial asthma in combination with Helicobacter pylori-associated chronic gastritis
- Autores: Pozdnyakova O.Y.1, Dyshekova N.V.1, Dokhkaeva A.Z.1
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Afiliações:
- Stavropol State Medical University of the Ministry of Healthcare of Russia
- Edição: Volume 10, Nº 2 (2024)
- Páginas: 20-24
- Seção: ORIGINAL STUDIES
- URL: https://journals.eco-vector.com/2412-4036/article/view/631819
- DOI: https://doi.org/10.18565/therapy.2024.2.20-24
- ID: 631819
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Resumo
Currently, there are very few studies on the frequency and nature of food sensitization in cases of isolated bronchial asthma (BA) and BA in combination with H. pylori-associated chronic gastritis (Hp-ACG).
The aim: to estimate the frequency and nature of food sensitization in patients with isolated BA and BA in combination with Hp-ACG.
Material and methods. 85 patients with bronchial asthma (BA) were divided into two groups: 1st group (main) – patients with BA in combination with Hp-ACG (n = 50), 2nd – patients with isolated BA (n = 35). All the participants of the research underwent clinical, laboratory, instrumental and allergological examination.
Results. In patients with isolated BA and BA in combination with Hp-ACG, very high and high levels of specific IgE and IgG to various food allergens (cow’s milk, pork, beef, chicken, cod, wheat, buckwheat, oatmeal) were identified. The most clinically significant food sensitization was observed in patients with severe uncontrolled BA in combination with Hp-ACG.
Conclusion. Food sensitization is a characteristic feature in patients with isolated BA and BA in combination with Hp-ACG. In case of severe persistent clinical course, frequent BA exacerbations, lack of the control over disease, it is necessary to check the level of total IgE and specific food IgE and IgG to study the nature and frequency of food sensitization and also for performing rational pharmacotherapy for patients with both isolated BA and in the case of comorbidity of BA with Hp-AHG.
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Sobre autores
Oksana Pozdnyakova
Stavropol State Medical University of the Ministry of Healthcare of Russia
Autor responsável pela correspondência
Email: oxana_stav@mail.ru
ORCID ID: 0000-0002-0208-7993
MD, Dr. Sci. (Medicine), professor of the Department of clinical pharmacology with a course of additional professional education
Rússia, 355017, Stavropol, 310 Mira St.Natalya Dyshekova
Stavropol State Medical University of the Ministry of Healthcare of Russia
Email: natalia.glebova9@yandex.ru
MD, postgraduate student of the Department of clinical pharmacology with a course of additional professional education
Rússia, 355017, Stavropol, 310 Mira St.Aza Dokhkaeva
Stavropol State Medical University of the Ministry of Healthcare of Russia
Email: aza.doxkaeva.94@mail.ru
MD, postgraduate student of the Department of clinical pharmacology with a course of additional professional education
Rússia, 355017, Stavropol, 310 Mira St.Bibliografia
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