Prediabetes: Therapy of carbohydrate metabolism disorders in patients with risk factors

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Article considers the key issues of management of patients with early carbohydrate metabolism disorders at the primary outpatient healthcare level. The most important tasks at this stage of medical care include increasing the detection of prediabetes during preventive medical examinations and health surveys, active recommendations to patients on lifestyle modification, as well as timely prescription of pharmacotherapy. Drugs used in this case should affect various pathological mechanisms of the development of carbohydrate metabolism disorders, helping to control insulin resistance, glycemia, prevent the transformation of prediabetes into type 2 diabetes mellitus and prevent complications.

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Sobre autores

Andrey Malyavin

Russian University of Medicine of the Ministry of Healthcare of Russia

Autor responsável pela correspondência
Email: maliavin@mail.ru
ORCID ID: 0000-0002-6128-5914

MD, Dr. Sci. (Medicine), professor, general secretary of Russian Scientific Medical Society of Internal Medicine (RSMSIM), professor of the Department of phthisiology and pulmonology of N.A. Semashko Scientific and Educational Institute of Clinical Medicine, chief external expert – pulmonologist of the Ministry of Healthcare of Russia for the Central Federal District

Rússia, 107150, Moscow, 39/2 Losinoostrovskaya St.

Ashot Mkrtumyan

Russian University of Medicine of the Ministry of Healthcare of Russia; A.S. Loginov Moscow Clinical Research Center of the Department of Healthcare of Moscow

Email: vagrashot@mail.ru
ORCID ID: 0000-0003-1316-5245

MD, Dr. Sci. (Medicine), professor, head of the Department of endocrinology of N.A. Semashko Scientific and Educational Institute of Clinical Medicine, head of the Scientific Department of endocrine and metabolic disorders, Honored Doctor of Russia

Rússia, 107150, Moscow, 39/2 Losinoostrovskaya St.; 127006, Moscow, 4 Dolgorukovskaya St.

Tatyana Adasheva

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: adashtv@mail.ru
ORCID ID: 0000-0002-3763-8994

MD, Dr. Sci. (Medicine), professor, member of the presidium of RSMSIM, professor of the Department of therapy and preventive medicine of N.A. Semashko Scientific and Educational Institute of Clinical Medicine

Rússia, 107150, Moscow, 39/2 Losinoostrovskaya St.

Laura Bolieva

North Ossetian State Medical Academy of the Ministry of Healthcare of Russia

Email: bolievalz@mail.ru
ORCID ID: 0000-0002-1820-7726

MD, Dr. Sci. (Medicine), professor, member of the presidium of RSMSIM, head of the Department of pharmacology with clinical pharmacology, Honored Doctor of North Ossetia-Alania Republic, chief external expert – pulmonologist, allergologist-immunologist of the Ministry of Healthcare of North Ossetia – Alania Republic

Rússia, 362019, Vladikavkaz, 40 Pushkinskaya St.

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2. Fig. 1. Diagnosis of early disorders of carbohydrate metabolism during medical examination and differential diagnosis with type 2 diabetes mellitus

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3. Fig. 2. Levels of disorders on the background of insulin resistance

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4. Fig. 3. Scheme of the dual action of the drug Sublette

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