Herbal medicinal products in treatment of respiratory infections


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

Current pandemic of the new coronavirus infection COVID-19 has highlighted the leading role of acute respiratory infections (including influenza and ARVI) in the structure of infectious diseases and their impact at socio-economic indicators. Herbal medicinal products play an important role in the symptomatic and pathogenetic treatment of these diseases. They provide a wide range of positive effects in combination with a low risk of adverse events, including comorbid patients and children. Current review presents the substantiation for the use of a Pelargonium sidoides extract-based medicine at the outpatient stage of providing medical care to acute respiratory diseases patients.

全文:

受限制的访问

作者简介

A. Vertkin

A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia

Email: kafedrakf0mail.ru.elibrary.ru
127473, Moscow, 20/1 Delegatskaya Str

M. Shamuilova

A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia

Email: kafedrakf0mail.ru
127473, Moscow, 20/1 Delegatskaya Str

G. Knorring

A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia

127473, Moscow, 20/1 Delegatskaya Str

参考

  1. Грипп. ВОЗ, 2018. Доступ: https://www.who.int/ru/news-room/factsheets/detail/influenza-(seasonal) (дата обращения - 01.10.20211. @@Influenza. World Health Organization, 2018. Available at: https://www.who.int/ru/news-room/factsheets/detai1/inf1uenza-(seasona1) (date of access - 01.10.2021) (In Russ.).
  2. О состоянии санитарно-эпидемиологического благополучия населения в Российской Федерации в 2016 году: государственный доклад. Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека. М. 2017; 220 с. @@On the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2016: state report. Federal Service for Supervision of Consumer Rights Protection and Human Welfare. Moscow. 2017; 220 pp. (In Russ.).
  3. Ющук Н.Д., Хадарцев О.С. Профилактика гриппа и острых респираторных вирусных инфекций с учетом особенности их эпидемического процесса. Инфекционные болезни: новости, мнения, обучение. 2018; 2: 44-51. @@Yushchuk N.D., Khadartsev O.S. Prevention of influenza and acute respiratory viral infections and their epidemic process characteristics. Infektsionnyye botezni: novosti, mneniya, obucheniye = Infectious Diseases: News, Views, Education. 2018; 2: 44-51 (In Russ.). doi: https://dx.doi.org/10.24411/2305-3496-2018-12004.
  4. Колбин А.С., Гомон Ю.М., Балыкина Ю.Е. с соавт. Социально-экономическое и глобальное бремя COVID-19. Качественная клиническая практика. 2021; 1: 24-34. @@Kolbin A.S., Gomon Yu.M., Balykina Yu.E. et at. Socioeconomic and global burden of COVID-19. Kachestvennaya ktinicheskaya praktika = Good Clinical Practice. 2021; 1: 24-34 (In Russ.). doi: https://dx.doi.org/10.37489/2588-0519-2021- 1-24-34.
  5. Patterson K.D., Pyle G.F. The geography and mortality of the 1918 influenza pandemic. Bull Hist Med. 1991; 65(1): 4-21.
  6. Johnson N.P, Mueller J. Updating the accounts: global mortality of the 1918-1920 «Spanish» influenza pandemic. Bull Hist Med. 2002; 76(1): 105-15.
  7. Available at: https://ourworldindata.org/coronavirus (date of access - 01.10.2021).
  8. Watkins K., Sridhar D. Pneumonia: a global cause without champions. Lancet. 2018; 392(10149): 718-19. doi: 10.1016/S0140-6736(18)31666-0.
  9. Верткин А.Л., Прохорович Е.А., Намазова Л.С. с соавт. Оптимизация эмпирической терапии внебольничной пневмонии у больных пожилого и старческого возраста. РМЖ. 2002; 16: 708-712. @@Vertkin A.L., Prokhorovich E.A., Namazova L.S. et al. Optimization of empiric therapy for community-acquired pneumonia in elderly and senile patients. Russkiy meditsinskiy zhurnal = Russian Medical Journal. 2002; 16: 708-712 (In Russ.).
  10. Anheyer D., Cramer H., Lauche R. et al. Herbal medicine in children with respiratory tract infection: Systematic review and meta-analysis. Acad Pediatr. 2018; 18(1): 8-19. doi: 10.1016/j.acap.2017.06.006.
  11. Клячкина И.Л., Рыбаченко В.В., Кнорринг ГЮ., Воронина Е.В. Опыт и перспективы системной энзимотерапии при лечении заболеваний дыхательных путей. Доктор.Ру. 2006; 2: 31-35. @@Klyachkina I.L., Rybachenko V.V., Knorring G.Yu., Voronina E.V. Experience and prospects of systemic enzyme therapy in the treatment of respiratory diseases. DoctorRu. 2006; 2: 31-35 (In Russ.).
  12. Chalumeneau M., Salannave B., Assathiany R. et al. [Connaisance et application par des pediatres deville de la conference de concensus sur les rhinopharyngites aigues de l'enfant]. Arch. Pediatr. 2000; 7(5): 481-88.
  13. Bladt S., Wagner H. From the Zulu medicine to the European phytomedicine Umckaloabo. Phytomedicine. 2007; 14(6): 2-4. doi: 10.1016/j. phymed.2006.11.030.
  14. Холодова И.Н., Холодов Д.И. Как снизить резистентность к антибактериальной терапии? Медицинский совет. 2017; 19: 84-89. [Kholodova I.N., Kholodov D.I. How to reduce resistance to antibacterial therapy? Meditsinskiy sovet = Medical Council. 2017; 19: 84-89 (In Russ.)]. doi: https://doi.org/10.21518/2079-701X-2017-19-84-89.
  15. Kolodziej H., Kiderlen A.F In vitro evaluation of antibacterial and immunomodulatory activities of Pelargonium reniforme, Pelargonium sidoides and related herbal drug рreparation EPs 7630. Phytomedicine. 2007, 14(6): 18-26. doi: 10.1016/j.phymed.2006.11.020.
  16. Григорян С.С., Гаращенко Т.И., Исаева Е.К. с соавт. Противовирусное действие препарата Умкалор на продукцию вируса in vitro. Детская оториноларингология. 2014; 2: 1-4. @@Grigoryan S.S., Garashchenko T.I., Isaeva E.K. et al. Antiviral effect of the drug Umckalor on the production of the virus in vitro. Detskaya otorinolaringologiya = Pediatric Otorhinolaryngology. 2014; 2: 1-4 (In Russ.).
  17. Roth M., Fang L., Stolz, D., Tamm M. Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells. 2019; 14(2): e0210702. doi: 10.1371/journal.pone.0210702.
  18. Keck T., Strobl A., Weinhaeusel A. et al. Pelargonium extract EPs 7630 in the treatment of human coronavirus-associated acute respiratory tract infections - a secondary subgroup-analysis of an open-label, uncontrolled clinical trial. Front Pharmacol. 2021; 12: 666546. doi: 10.3389/ fphar.2021.666546.
  19. Bereznoy V., Riley D., Wassmer G., Heger M. Efficacy of extract of Pelargonium sidoides in children with acute non-group A beta-hemolytic Streptococcus tonsillopharyngitis: A randomized, double-blind, placebo-controlled trial. Altern Ther Health Med. 2003; 9(5): 68-79.
  20. Conrad A., Jung I., Tioua D. et al. Extract of Pelargonium sidoides (EPs 7630) inhibits the interactions of group A-streptococci and host epithelia in vitro. Phytomedicine. 2007;14(6): 52-59. doi: 10.1016/j.phymed.2006.11.018.
  21. Janecki A., Conrad A., Engels I. et al. Evaluation of an aqueous-ethanolic extract from Pelargonium sidoides (EPs 7630) for its activity against group A-streptococci adhesion to human HEp-2 epithelial cells. J Ethnopharmacol. 2011; 133(1): 147-52. doi: 10.1016/j.jep.2010.09.018.
  22. Matthys H., Heger M. Treatment of acute bronchitis with liquid herbal drug preparation from Pelargonium sidoides (EPs 7630): A randomized, double-blind, placebo-controlled multicentre study. Curr Res Opin. 2007; 23(2): 323-31. doi: 10.1185/030079906X167318.
  23. Елкина Т.Н., Грибанова О.А. Монотерапия острых респираторных инфекций препаратом «Умкалор». РМЖ. 2008; 16: 1968-1971. @@Elkina T.N., Gribanova O.A. Monotherapy of acute respiratory infections with the drug Umckalor Russkiy meditsinskiy zhurnal = Russian Medical Journal. 2008, 16: 1968-1971 (In Russ.).
  24. Park S.M., Min B.G., Jung J.Y. et al. Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo. BMC Complement Altern Med. 2018; 18(1): 20. doi: 10.1186/s12906-018-2088-x.
  25. Peric A., Vezmar Kovacevic S., Barac A. et al. Effects of Pelargonium sidoides extract on chemokine levels in nasal secretions of patients with non-purulent acute rhinosinusitis. J Drug Assess. 2020; 9(1): 145-50. doi: 10.1080/21556660.2020.1838176.
  26. Haidvogl M., Heger M. Treatment effect and safety of EPs 7630-solution in acute bronchitis in childhood: report of a multicentre observational study. Phytomedicine. 2007; 14(Suppl 6): 60-64. doi: 10.1016/j.phymed.2006.11.014.
  27. Kolodziej H. Antimicrobial, antiviral and immunomodulatory activity studies of Pelargonium sidoides (EPs 7630) in the context of health promotion. Pharmaceuticals. 2011; 4(10): 1295-314. doi: 10.3390/ph4101295.
  28. Witte K., Koch E., Volk H.-D. et al. The Pelargonium Sidoides extract EPs 7630 drives the innate immune defense by activating selected map kinase pathways in human monocytes. PLoS One. 2015; 10 (9): e0138075. doi: 10.1371/journal.pone.0138075.
  29. Luna L.A. Jr, Bachi A.L.L., Novaes e Brito R.R. et al. Immune responses induced by Pelargonium sidoides extract in serum and nasal mucosa of athletes after exhaustive exercise: Modulation of secretory IgA, IL-6 and IL-15. Phytomedicine. 2011; 18 (4): 303-08. doi: 10.1016/j. phymed.2010.08.003.
  30. Matthys H., Kamin W., Funk P, Heger M. Pelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and children. Phytomedicine. 2007; 14(Suppl 6): 69-73. doi: 10.1016/j.phymed.2006.11.015.
  31. Dome L., Schuster R. [Umckaloabo - a phytotherapeutic alternative for acute bronchitis in childhood?] Arztez Naturheilverf. 1996; 37: 216-22.
  32. Haidvogl M., Schuster R., Heger M. [Acute bronchitis in children - multicenter study on the effectiveness and tolerability of the phytoterapeutic Umckaloabo]. Z Phytoterapie. 1996; 17: 300-13.
  33. Konig I. [Respiratory tract therapy on a natural basis]. Therapie Woche. 1995; 45: 1123-26.
  34. Крюков А.И., Кунельская Н.Л., Ивойлов А.Ю. с соавт. Клиническая эффективность Pelargonium sidoides - EPs 7630 в комплексной терапии детей с хроническим аденоидитом, перенесших аденотомию. Медицинский совет. 2017; 16: 28-32. @@Kryukov A.I., Kunelskaya N.L., Ivoilov A.Yu. et al. Clinical efficacy of pelargonium sidoides EPS® 7630 in complex therapy of children with chronic adenoiditis, who has undergone adenoidectomy. Meditsinskiy sovet = Medical Council. 2017; 16: 28-32 (In Russ.). doi: https://doi.org/10.21518/2079-701X-2017-16-28-32.
  35. Bereznoy V.V., Riley D.S., Wassmer G., Heger M. Efficacy of extract of Pelargonium sidoides in children with acute non-group Abeta-hemolytis Streptococcus tonsillopharygits; a randomized, double-blind, placebo-controlled trial. Altern Ther Health Med. 2003; 9(5): 68-79.
  36. Chuchalin A.G., Berman E., Lehmacher W. Treatment of acute bronchitis in adults with a Pelargonium sidoides preparation (EPs7630); A randomized, double-blind, placebo-controlled trial. Explore (NY). 2005; 1(6): 437-45. doi: 10.1016/j.explore.2005.08.009.
  37. Чучалин А.Г, Берман Б., Лемахер В. Лечение острого бронхита у взрослых экстрактом пеларгонии сидовидной (Pelargonium sidoides; EPs 7630): рандомизированное двойное слепое плацебо-контролируемое исследование. Пульмонология. 2007; 6: 49-55. @@Chuchalin A.G., Berman В., Lemakher V. Treatment of acute bronchitis in adults with extract of pelargonium sidoides: a randomised, double-blind, placebo controlled trial. Pul'monologiya = Pulmonology. 2007; 6: 49-55 (In Russ.).
  38. Agbabiaka T.B., Guo R., Ernst E. Pelargonium sidoides for acute bronchitis: a systematic review and meta-analysis. Phytomedicine. 2008; 15(5): 378-85. doi: 10.1016/j.phymed.2007.11.023. Epub 2008 Jan 28. Erratum in: Phytomedicine. 2009; 16(8): 798-99.
  39. Matthys H., Heger M. Treatment of acute bronchitis with a liquid herbal drug preparation from Pelargonium sidoides (EPs 7630): A randomized, double-blind, placebo-controlled, multicentre study. Curr Med Res Opin. 2007; 23(2): 323-31. doi: 10.1185/030079906X167318.
  40. Bachert C., Schapowal A., Funk P, Kieser M. Treatment of acute rhinosinusitis with the preparation from Pelargonium sidoides EPs 7630: A randomized, double-blind, placebo-controlled trial. Rhinology. 2009; 47(1): 51-58.
  41. Timmer A., Gunther J., Motschall E. et al. Pelargonium sidoides extract for treating acute respiratory tract infections. Cochrane Database Syst Rev. 2013; 10: CD006323. doi: 10.1002/14651858.CD006323.pub3.
  42. Anheyer D., Cramer H., Lauche R. et al. Herbal medicine in children with respiratory tract infection: Systematic review and meta-analysis. Acad Pediatr 2018; 18(1): 8-19. doi: 10.1016/j.acap.2017.06.006.
  43. Careddu D., Pettenazzo A. Pelargonium sidoides extract EPs 7630: a review of its clinical efficacy and safety for treating acute respiratory tract infections in children. Int J Gen Med. 2018; 11: 91-98. doi: 10.2147/IJGM.S154198.
  44. Seifert G., Brandes-Schramm J., Zimmermann A. et al. Faster recovery and reduced paracetamol use - a meta-analysis of EPs 7630 in children with acute respiratory tract infections. BMC Pediatr 2019; 19(1): 119. doi: 10.1186/s12887-019-1473-z.

补充文件

附件文件
动作
1. JATS XML
下载

版权所有 © Bionika Media, 2021
##common.cookie##