Reactivation of cytomegalovirus infection in a rheumatoid arthritis patient with immunosuppressive therapy in the background


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According to the literature data, the treatment of autoimmune rheumatological diseases with the use of basic anti-inflammatory drugs and genetically engineered biological agents may be accompanied by the reactivation of latent infections, including viral ones. Article presents a clinical case of the curation of a patient with rheumatoid arthritis, in which reactivation of cytomegalovirus (CMV) infection against the background of immunosuppressive therapy was observed.

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作者简介

Anton Budko

M.V. Lomonosov Moscow State University

resident of the 2nd year of the Department of internal diseases of the Faculty of fundamental medicine

Olga Georginova

M.V. Lomonosov Moscow State University

Email: olga.georginova@gmail.com
PhD in Medicine, assistant at the Department of internal medicine of the Faculty of fundamental medicine, therapist-rheumatologist at the Department of specialized medical care of the Department of the Medical Research and Educational Center

参考

  1. Насонов Е.Л., Каратеев Д.Е., Балабанова Р.М. Ревматоидный артрит. В. кн.: Ревматология. Национальное руководство. Под ред. Е.Л. Насонова, В.А. Насоновой. М.: ГЭОТАР-Медиа. 2008; с. 290-331. [Nasonov E.L., Karateev D.E., Balabanova R.M. Rheumatoid arthritis. In: Rheumatology. National guide. Ed. by E.L. Nasonova, V.A. Nasonova. Moscow: GEOTAR-Media. 2008; pp. 290-331 (In Russ.)]. ISBN: 978-5-9704-0672-4.
  2. Bullock J., Rizvi S., Saleh A.M. et al. Rheumatoid arthritis: A brief overview of the treatment. Med Princ Pract. 2018; 27(6): 501-7. https://dx.doi.org/10.1159/000493390.
  3. Chopra A., Abdel-Nasser A. Epidemiology of rheumatic musculoskeletal disorders in the developing world. Best Pract Res Clin Rheumatol. 2008; 22(4): 583-604. https://dx.doi.org/10.1016/j.berh.2008.07.001.
  4. Фоломеева О.М., Галушко Е.А., Эрдес Ш.Ф. Распространенность ревматических заболеваний в популяциях взрослого населения России и США. Научно-практическая ревматология. 2008; 4: 4-13. [Folomeeva O.M., Galushko E.A., Erdes Sh.F. Prevalence of rheumatic diseases in adult populations of Russian Federation and USA. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2008; 4: 4-13 (In Russ.)]. https://dx.doi.org/10.14412/1995-4484-2008-529.
  5. Клинические рекомендации. Ревматоидный артрит (утв. Минздравом России). Ассоциация ревматологов России. 2018. ID: КР 250. Доступ: https://legalacts.ru/doc/klinicheskie-rekomendatsii-revmatoidnyi-artrit-utv-minzdravom-rossii (дата обращения - 02.04.2021). [Clinical guidelines. Rheumatoid arthritis (approved by Ministry of Healthcare of Russia). Association of Rheumatologists of Russia. ID: KP 250. URL: https://legalacts.ru/doc/klinicheskie-rekomendatsii-revmatoidnyi-artrit-utv-minzdravom-rossii (date of access - 02.04.2021).
  6. Lin T.C., Yoshida K., Tedeschi S.K. et al. Risk of hepatitis B. virus reactivation in patients with inflammatory arthritis receiving disease-modifying antirheumatic drugs: A systematic review and meta-analysis. Arthritis Care Res (Hoboken). 2018; 70(5): 724-31. https://dx.doi.org/10.1002/acr.23346.
  7. Sztajnbok F., Boechat N.L., Oliveira S.K. et al. Latent tuberculosis infection in patients with juvenile idiopathic arthritis undergoing methotrexate therapy: A longitudinal study with TST and ELISPOT. Pediatr Rheumatol Online J. 2014; 12: 17. https://dx.doi.org/10.1186/1546-0096-12-17.
  8. Grove M.L., Hassell A.B., Hay E.M., Shadforth M.F. Adverse reactions to disease modifying anti-rheumatic drugs in clinical practice. QJM. 2001; 94(6): 309-19. https://dx.doi.org/10.1093/qjmed/94.6.309.
  9. Thomas K., Vassilopoulos D. Infections in patients with rheumatoid arthritis in the era of targeted synthetic therapies. Mediterr J. Rheumatol. 2020; 31(Suppl 1): 129-36. https://dx.doi.org/10.31138/mjr.31.1.129.
  10. Rasha H.B., Reham A.D., Eman M.E. et al. Elevated cytomegalovirus and Epstein-Barr virus burden in rheumatoid arthritis: A true pathogenic role or just a coincidence. The Egyptian Rheumatologist. 2019; 41(4): 255-59. https://dx.doi.org/10.1016/j.ejr.2019.03.003.
  11. Febres-Aldana A.J., Febres-Aldana C.A., Dvir K. et al. Reactivation of Epstein-Barr virus presenting as massive splenomegaly after initiation of golimumab treatment. Case Rep Hematol. 2020; 2020: 3641813. https://dx.doi.org/10.1155/2020/3641813.
  12. McKeown E., Pope J.E., Leaf S. Epstein-Barr virus (EBV) prevalence and the risk of reactivation in patients with inflammatory arthritis using anti-TNF agents and in those who are biologic naive. Open Rheumatol J. 2009; 3: 30-34. https://dx.doi.org/10.2174/1874312900903010030.
  13. Komura T., Ohta H., Nakai R. et al. Cytomegalovirus reactivation induced acute hepatitis and gastric erosions in a patient with rheumatoid arthritis under treatment with an anti-IL-6 receptor antibody, tocilizumab. Intern Med. 2016; 55(14): 1923-27. https://dx.doi.org/10.2169/internalmedicine.55.5981.
  14. Van Duin D., Miranda C., Husni E. Cytomegalovirus viremia, pneumonitis, and tocilizumab therapy. Emerg Infect Dis. 2011; 17(4): 754-56. https://dx.doi.org/10.3201/eid1706.101057.
  15. Georg H., Burkhard J. M., Yvonne J. et al. Cytomegalovirus retinitis in a patient treated with anti-tumor necrosis factor alpha antibody therapy for rheumatoid arthritis. Clin Infect Dis. 2004; 39(9): e88-94. https://dx.doi.org/10.1086/425123.
  16. Gardine B.J., Haas E.M., Bailey R.C. et al. Reactivation of latent cytomegalovirus infection in patients with rheumatologic disease: a case-control study. Rheumatol Int. 2019; 39(7): 1229-40. https://dx.doi.org/10.1007/s00296-019-04324-6.
  17. Государственный реестр лекарственных средств. В. 2 т. М.: Медицинский совет. 2009; с. 568. [State register of medicines. In 2 vol. Moscow: Meditsinskiy sovet = Medical Council. 2009; p. 568 (In Russ.)]. ISBN: 978-5-904523-01-5, 978-5-904523-03-9.
  18. Miceli-Richard C., Gestermann N., Amiel C. et al. Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies. Arthritis Res Ther. 2009; 11(3): R77. https://dx.doi.org/10.1186/ar2708.

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