Competing course of COVID-19 coronavirus infection caused by the SARS-CoV-2 virus and systemic lupus erytheis with multiorganic complications

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Patients with systemic lupus erythematosus (SLE) are a vulnerable group in terms of the viewpoint of the COVID-19 pandemic impact at disease management. Presented clinical observation demonstrates a combination of two deadly dangerous diseases: coronavirus infection and SLE. Clinical course of high-grade SLE with pulmonary damage in the form of hemorrhagic pulmonitis, complicated by the development of bilateral polysegmental pneumonia (CT pattern of stages 3–4), in the described example, required performing of ALV, antiviral and pathogenetic therapy for COVID-19, including systemic glucocorticoids use, treatment of secondary bacterial, fungal and cytomegalovirus infections, as well as performing renal replacement therapy and sessions of high-volume plasma exchange due to acute renal injury.

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作者简介

Nadia Frolova

City Clinical Hospital No. 52 of the Department of Healthcare of Moscow; A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia

编辑信件的主要联系方式.
Email: nadiya.frolova@yandex.ru
ORCID iD: 0000-0002-6086-5220

PhD in Medical Sciences, Associate Professor of the Department of Nephrology, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia, Deputy Chief Physician for Nephrological Care of City Clinical Hospital No. 52 of the Department of Healthcare of Moscow

俄罗斯联邦, Moscow; Moscow

Natalya Terentyeva

City Clinical Hospital No. 52 of the Department of Healthcare of Moscow

Email: natterentyeva14@mail.ru
ORCID iD: 0000-0003-0614-8076

Nephrologist at 2nd Department of Nephrology

俄罗斯联邦, Moscow

Rustam Iskhakov

City Clinical Hospital No. 52 of the Department of Healthcare of Moscow

Email: stamius@yandex.ru
ORCID iD: 0000-0003-2850-4465

Head of the Department of Resuscitation and Intensive Care No. 2 for Nephrological Patients

俄罗斯联邦, Moscow

Sergey Usatyuk

City Clinical Hospital No. 52 of the Department of Healthcare of Moscow

Email: usatuk-doc@mail.ru
ORCID iD: 0000-0002-8742-3860

Head of the 2nd Department of Nephrology

俄罗斯联邦, Moscow

Zinaida Mutovina

City Clinical Hospital No. 52 of the Department of Healthcare of Moscow; Central State Medical Academy of the Administration of the President of the Russian Federation

Email: zmutovina@mail.ru
ORCID iD: 0000-0001-5809-6015

PhD in Medical Sciences, Associate Professor of the Department of Therapy, Cardiology and Functional Diagnostics with the Course of Nephrology, Central State Medical Academy of the Administration of the President of the Russian Federation, Head of the Department of Rheumatology No. 1 of City Clinical Hospital No. 52 of the Department of Healthcare of Moscow

俄罗斯联邦, Moscow; Moscow

Sergey Andreev

City Clinical Hospital No. 52 of the Department of Healthcare of Moscow

Email: nerowolf@mail.ru
ORCID iD: 0000-0002-9147-4636

Head of the Department of Clinical Pharmacology

俄罗斯联邦, Moscow

Galina Volgina

A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia

Email: volginagv@mail.ru
ORCID iD: 0000-0002-7771-4074

MD, Professor of the Department of Nephrology

俄罗斯联邦, Moscow

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2. Fig. 1. Computed tomography of patient R.'s lungs dated September 21, 2021.

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3. Fig. 2. Computed tomography of patient N.'s lungs dated September 30, 2021.

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4. Fig. 3. Computed tomography of patient N.'s lungs dated October 27, 2021.

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5. Fig. 4. Computed tomography of patient N.'s lungs dated October 30, 2021.

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6. Fig. 5. Computed tomography of patient N.'s lungs dated November 21, 2021

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7. Fig. 6. Histological examination of a kidney biopsy specimen of patient N. from January 27, 22

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