Bullous epidermolysis is a congenital disease characterized by skin vulnerability due to the formation of blisters and erosion on the skin and mucous membranes, which makes it difficult for a child to eat naturally. The problem of providing the necessary nutrients to children with this serious illness remains relevant. The article shows its own clinical experience in the use of modern enteral nutritional mixtures in a child with epidermolysis bullosa. Given the skin manifestations, the possibility of infection of the catheter for prolonged parenteral nutrition, children with bullous epidermolysis are not recommended for prolonged use of parenteral nutrition, so the use of modern mixtures for enteral nutrition remains the method of choice.