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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Clinical nutrition and metabolism</journal-id><journal-title-group><journal-title xml:lang="en">Clinical nutrition and metabolism</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническое питание и метаболизм</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2658-4433</issn><issn publication-format="electronic">2782-2974</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">321122</article-id><article-id pub-id-type="doi">10.17816/clinutr321122</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The choice of enteral formula in patients in the acute period of critical ill with brain damage in the neurocritical care unit</article-title><trans-title-group xml:lang="ru"><trans-title>Выбор смеси для энтерального питания у пациентов в остром периоде тяжёлого состояния с повреждением головного мозга в отделении нейрореанимации</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1807-7546</contrib-id><contrib-id contrib-id-type="spin">9435-0854</contrib-id><name-alternatives><name xml:lang="en"><surname>Krylov</surname><given-names>Kirill Yu.</given-names></name><name xml:lang="ru"><surname>Крылов</surname><given-names>Кирилл Юрьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>kkrylov@nsi.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9976-8903</contrib-id><contrib-id contrib-id-type="spin">4974-9195</contrib-id><name-alternatives><name xml:lang="en"><surname>Sviridov</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Свиридов</surname><given-names>Сергей Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>sergey.sviridov.59@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1232-6767</contrib-id><contrib-id contrib-id-type="spin">6199-6980</contrib-id><name-alternatives><name xml:lang="en"><surname>Vedenina</surname><given-names>Irina V.</given-names></name><name xml:lang="ru"><surname>Веденина</surname><given-names>Ирина Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Assistant professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>viv54@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3273-890X</contrib-id><contrib-id contrib-id-type="spin">5617-6196</contrib-id><name-alternatives><name xml:lang="en"><surname>Yagubyan</surname><given-names>Ruben S.</given-names></name><name xml:lang="ru"><surname>Ягубян</surname><given-names>Рубен Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>admin@airkafrgmu.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">National Medical Research Center for Neurosurgery</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр нейрохирургии имени академика Н.Н. Бурденко</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-05-31" publication-format="electronic"><day>31</day><month>05</month><year>2023</year></pub-date><volume>4</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>29</fpage><lpage>37</lpage><history><date date-type="received" iso-8601-date="2023-03-07"><day>07</day><month>03</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-04-07"><day>07</day><month>04</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/2658-4433/article/view/321122">https://journals.eco-vector.com/2658-4433/article/view/321122</self-uri><abstract xml:lang="en"><p>Nutritional support is an important and integral part of the treatment process for critically ill patients. Patients after neurosurgical interventions and patients with damage to the central nervous system, for example, due to acute ischemic stroke, may be due to the severity of the condition in the intensive care unit. This is a separate category of patients and nutritional support for this category of patients has its own characteristics. Enteral nutrition, as the most physiological type of nutrition, should be an integral part of the treatment process in the intensive care unit. In patients in the acute period of a severe condition with brain damage, in addition to the metabolic response to damage, there are also factors that limit the implementation of enteral nutrition: the brain damage itself, being in intensive care, and methods of intensive therapy. The choice of an enteral formula in this category of patients is complex and fundamental to provide adequate nutritional support to cover energy and protein requirements. The purpose of this scientific review is to highlight the issues of choosing a mixture for enteral nutrition of patients in the neurocritical care unit who are in the acute period of a critical ill.</p></abstract><trans-abstract xml:lang="ru"><p>Нутритивная поддержка является важной и неотъемлемой частью лечебного процесса для пациентов в интенсивной терапии. По причине тяжести состояния пациенты после нейрохирургических вмешательств и пациенты с повреждением центральной нервной системы, например вследствие острого нарушения мозгового кровообращения, могут находиться в отделении интенсивной терапии. Проведение нутритивной поддержки данной категории пациентов имеет свои особенности. Энтеральное питание, как наиболее физиологичный вид питания, должно являться неотъемлемой частью лечебного процесса в отделении интенсивной терапии. У пациентов, находящихся в остром периоде тяжёлого состояния с повреждением головного мозга, к метаболическому ответу на повреждение добавляются также факторы, лимитирующие проведение энтерального питания: собственно повреждение головного мозга, нахождение в интенсивной терапии и методы интенсивной терапии. Выбор смеси для энтерального питания у данной категории пациентов является сложным и основополагающим для проведения адекватной нутритивной поддержки с покрытием потребностей в энергии и белке. В данном научном обзоре освещаются вопросы выбора смеси для энтерального питания пациентов отделения нейрореанимации, находящихся в остром периоде тяжёлого состояния.</p></trans-abstract><kwd-group xml:lang="en"><kwd>nutritional support</kwd><kwd>brain damage</kwd><kwd>neurocritical care</kwd><kwd>enteral nutrition</kwd><kwd>intensive therapy</kwd><kwd>enteral formula</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нутритивная поддержка</kwd><kwd>повреждение головного мозга</kwd><kwd>нейрореанимация</kwd><kwd>энтеральное питание</kwd><kwd>интенсивная терапия</kwd><kwd>смесь для энтерального питания</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Lee JS, Kang JE, Park SH, et al. Nutrition and Clinical Outcomes of Nutrition Support in Multidisciplinary Team for Critically Ill Patients. 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