<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Clinical nutrition and metabolism</journal-id><journal-title-group><journal-title xml:lang="en">Clinical nutrition and metabolism</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническое питание и метаболизм</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2658-4433</issn><issn publication-format="electronic">2782-2974</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">79378</article-id><article-id pub-id-type="doi">10.17816/clinutr79378</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Venous access for parenteral nutrition: Changes in Europe and North America over the past 12 years</article-title><trans-title-group xml:lang="ru"><trans-title>Венозный доступ для парентерального питания: что изменилось за последние 12 лет в Европе и Северной Америке?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8463-2600</contrib-id><contrib-id contrib-id-type="spin">3692-5202</contrib-id><name-alternatives><name xml:lang="en"><surname>Kurmukov</surname><given-names>Ildar A.</given-names></name><name xml:lang="ru"><surname>Курмуков</surname><given-names>Илдар Анварович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>kurmukovia@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0197-7721</contrib-id><contrib-id contrib-id-type="spin">6876-7701</contrib-id><name-alternatives><name xml:lang="en"><surname>Obukhova</surname><given-names>Olga A.</given-names></name><name xml:lang="ru"><surname>Обухова</surname><given-names>Ольга Аркадьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук</p></bio><email>obukhova0404@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2021-10-28" publication-format="electronic"><day>28</day><month>10</month><year>2021</year></pub-date><pub-date date-type="pub" iso-8601-date="2021-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2021</year></pub-date><volume>2</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>5</fpage><lpage>12</lpage><history><date date-type="received" iso-8601-date="2021-08-31"><day>31</day><month>08</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-10-08"><day>08</day><month>10</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Kurmukov I.A., Obukhova O.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Курмуков И.А., Обухова О.А.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Kurmukov I.A., Obukhova O.A.</copyright-holder><copyright-holder xml:lang="ru">Курмуков И.А., Обухова О.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/2658-4433/article/view/79378">https://journals.eco-vector.com/2658-4433/article/view/79378</self-uri><abstract xml:lang="en"><p>This article provides an overview of the significant changes in clinical practices since the publication of the European Association for Clinical Nutrition and Metabolism guidelines on providing vascular access for parenteral nutrition regarding the choice of vascular access and prevention and treatment of the most common and important complications of long-term venous access, the catheter-associated bloodstream infection, and internal lumen obstruction of catheters.</p> <p>The preferred vascular access for parenteral nutrition for medium- to long-term parenteral nutrition is the tunneled central venous catheter, peripherally inserted central catheter, or a fully implantable port system, which is now largely determined by the underlying disease, near-term prognosis and patient comfort, and short-term parenteral nutrition in a hospital that largely depends on the capabilities of a particular medical institution. Strict adherence to modern standard measures for infection control and care of venous access and infusion lines, hand hygiene, and appropriate training of medical personnel, patients, and their caregivers are currently the most reliable and effective methods to prevent catheter-associated bloodstream infection. Taurolidine “catheter lock” is used as an additional measure.</p> <p>In most cases, the occlusion of the inner canal of the catheter can be eliminated by drug methods; however, its effectiveness directly depends on the correspondence of the chosen drug to the cause of the occlusion. Generally, changes in recent years have significantly reduced the incidence and risk of parenteral nutrition complications associated with vascular access.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен обзор существенных изменений клинической практики, произошедших со времени публикации рекомендаций Европейской ассоциации клинического питания и метаболизма по обеспечению сосудистого доступа для парентерального питания в отношении выбора сосудистого доступа, профилактики и лечения наиболее частых осложнений длительно используемого венозного доступа ― катетерассоциированной инфекции кровотока и обструкции внутреннего просвета катетеров.</p> <p>Предпочитаемый сосудистый доступ при средне- и долговременном парентеральном питании ― туннелируемый центральный венозный катетер, периферически имплантируемый центральный венозный катетер или полностью имплантируемая порт-система ― теперь в значительной степени определяется основным заболеванием, ближайшим прогнозом жизни и комфортом пациента, а при кратковременном парентеральном питании в стационаре ― в большей степени зависит от возможностей конкретного лечебного учреждения. Строгое соблюдение современных стандартных мер инфекционного контроля и ухода за венозным доступом и инфузионными линиями, гигиена рук, а также соответствующее обучение медицинского персонала, пациентов и ухаживающих за ними лиц являются в настоящее время самыми надёжными и эффективными способами профилактики катетерассоциированной инфекции кровотока. В качестве дополнительной меры применяется «замок катетера» тауролидином. Окклюзия внутреннего канала катетера в большинстве случаев может быть устранена лекарственным методом, однако его эффективность непосредственно зависит от соответствия выбранного препарата причине окклюзии.</p> <p>В целом, произошедшие в последние годы изменения позволили значительно уменьшить частоту и опасность осложнений парентерального питания, связанных с сосудистым доступом.</p></trans-abstract><kwd-group xml:lang="en"><kwd>venous access</kwd><kwd>parenteral nutrition</kwd><kwd>catheter-associated bloodstream infection</kwd><kwd>occlusion/obstruction of the catheter</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>венозный доступ</kwd><kwd>парентеральное питание</kwd><kwd>катетерассоциированная инфекция кровотока</kwd><kwd>КАИК</kwd><kwd>окклюзия венозного катетера</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Pittiruti M, Hamilton H, Biffi R, et al. ESPEN Guidelines on parenteral nutrition: central venous catheters (access, care, diagnosis and therapy of complications). Clin Nutr. 2009;28(4):365–377. doi: 10.1016/j.clnu.2009.03.015</mixed-citation><mixed-citation xml:lang="ru">Pittiruti M., Hamilton H., Biffi R., et al. ESPEN Guidelines on parenteral nutrition: central venous catheters (access, care, diagnosis and therapy of complications) // Clin Nutr. 2009. Vol. 28, N 4. Р. 365–377. doi: 10.1016/j.clnu.2009.03.015</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">ESPEN Guidelines &amp; Consensus Papers [updated 07 September 2021]. Available from: https://www.espen.org/guidelines-home/espen-guidelines. Accessed: 07.09.2021.</mixed-citation><mixed-citation xml:lang="ru">ESPEN Guidelines &amp; Consensus Papers [updated 07 September 2021]. Режим доступа: https://www.espen.org/guidelines-home/espen-guidelines. Дата обращения: 07.09.2021.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Pironi L, Boeykens K, Bozzetti F, et al. ESPEN guideline on home parenteral nutrition. Clin Nutr. 2020;39(6):1645–1666. doi: 10.1016/j.clnu.2020.03.005</mixed-citation><mixed-citation xml:lang="ru">Pironi L., Boeykens K., Bozzetti F., et al. ESPEN guideline on home parenteral nutrition // Clin Nutr. 2020. Vol. 39, N 6. Р. 1645–1666. doi: 10.1016/j.clnu.2020.03.005</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Obukhova OA, Kashia SR, Kurmukov IA, et al. The effect of complete parenteral nutrition on metabolic processes in the early postoperative period in cancer patients. General Resuscitation. 2011;7(2):51–55. (In Russ).</mixed-citation><mixed-citation xml:lang="ru">Обухова О.А., Кашия Ш.Р., Курмуков И.А., и др. Влияние полного парентерального питания на метаболические процессы в раннем послеоперационном периоде у онкологических больных // Общая реаниматология. 2011. Т. 7, № 2. С. 51–55.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Pronina A, Kurmukov I, Kashia S. Totally implantable venous access ports (TIVAPs) in cancer patients (pts): safety of implantation in intensive care unit (ICU) and opportunity for immediate use. Critical Care. 2019;23(Suppl 2):72–193.</mixed-citation><mixed-citation xml:lang="ru">Pronina A., Kurmukov I., Kashia S. Totally implantable venous access ports (TIVAPs) in cancer patients (pts): safety of implantation in intensive care unit (ICU) and opportunity for immediate use // Critical Care. 2019. Vol. 23, Suppl. 2. Р. 72–193.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Kovacevich DS, Corrigan M, Ross VM, et al. American Society for Parenteral and Enteral Nutrition guidelines for the selection and care of central venous access devices for adult home parenteral nutrition administration. J Parenter Enteral Nutr. 2019;43(1):15–31. doi: 10.1002/jpen.1455</mixed-citation><mixed-citation xml:lang="ru">Kovacevich D.S., Corrigan M., Ross V.M., et al. American Society for Parenteral and Enteral Nutrition guidelines for the selection and care of central venous access devices for adult home parenteral nutrition administration // J Parenter Enteral Nutr. 2019. Vol. 43, N 1. Р. 15–31. doi: 10.1002/jpen.1455</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Hortencio TD, Arendt BM, Teterina A, et al. Changes in home parenteral nutrition practice based on the canadian home parenteral nutrition patient registry. J Parenter Enteral Nutr. 2017;41(5): 830–836. doi: 10.1177/0148607115609289</mixed-citation><mixed-citation xml:lang="ru">Hortencio T.D., Arendt B.M., Teterina A., et al. Changes in home parenteral nutrition practice based on the canadian home parenteral nutrition patient registry // J Parenter Enteral Nutr. 2017. Vol. 41, N 5. Р. 830–836. doi: 10.1177/0148607115609289</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Saqui O, Fernandes G, Allard J. Central venous catheter infection in Canadian home parenteral nutrition patients: a 5-year multicenter retrospective study. Br J Nurs. 2020;29(8):S34–S42. doi: 10.12968/bjon.2020.29.8.S34</mixed-citation><mixed-citation xml:lang="ru">Saqui O., Fernandes G., Allard J. Central venous catheter infection in Canadian home parenteral nutrition patients: a 5-year multicenter retrospective study // Br J Nurs. 2020. Vol. 29, N 8. Р. S34–S42. doi: 10.12968/bjon.2020.29.8.S34</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Vashi PG, Virginkar N, Popiel B, et al. Incidence of and factors associated with catheter-related bloodstream infection in patients with advanced solid tumors on home parenteral nutrition managed using a standardized catheter care protocol. BMC Infect Dis. 2017. 30;17(1):372. doi: 10.1186/s12879-017-2469-7</mixed-citation><mixed-citation xml:lang="ru">Vashi P.G., Virginkar N., Popiel B., et al. Incidence of and factors associated with catheter-related bloodstream infection in patients with advanced solid tumors on home parenteral nutrition managed using a standardized catheter care protocol // BMC Infect Dis. 2017. Vol. 17, N 1. Р. 372. doi: 10.1186/s12879-017-2469-7</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Wouters Y, Causevic E, Klek S, et al. Use of catheter lock solutions in patients receiving home parenteral nutrition: a systematic review and individual-patient data meta-analysis. J Parenter Enteral Nutr. 2020;44(7):1198–1209. doi: 10.1002/jpen.1761</mixed-citation><mixed-citation xml:lang="ru">Wouters Y., Causevic E., Klek S., et al. Use of catheter lock solutions in patients receiving home parenteral nutrition: a systematic review and individual-patient data meta-analysis // J Parenter Enteral Nutr. 2020. Vol. 44, N 7. Р. 1198–1209. doi: 10.1002/jpen.1761</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Gundogan K, Dave NJ, Griffith DP, et al. Ethanol lock therapy markedly reduces catheter-related blood stream infections in adults requiring home parenteral nutrition: a retrospective study from a tertiary medical center. J Parenter Enteral Nutr. 2020;44(4):661–667. doi: 10.1002/jpen.1698</mixed-citation><mixed-citation xml:lang="ru">Gundogan K., Dave N.J., Griffith D.P., et al. Ethanol lock therapy markedly reduces catheter-related blood stream infections in adults requiring home parenteral nutrition: a retrospective study from a tertiary medical center // J Parenter Enteral Nutr. 2020. Vol. 44, N 4. Р. 661–667. doi: 10.1002/jpen.1698</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Dibb M, Lal S. Home parenteral nutrition: vascular access and related complications. Nutr Clin Pract. 2017;32(6):769–776. doi: 10.1177/0884533617734788</mixed-citation><mixed-citation xml:lang="ru">Dibb M., Lal S. Home parenteral nutrition: vascular access and related complications // Nutr Clin Pract. 2017. Vol. 32, N 6. Р. 769–776. doi: 10.1177/0884533617734788</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Allan PJ, McMahon M, Abraham A, et al. Reduced need for replacement of long term parenteral nutrition catheters following endoluminal brushing. Clin Nutr. 2015;34(1):146–150. doi: 10.1016/j.clnu.2014.02.006</mixed-citation><mixed-citation xml:lang="ru">Allan P.J., McMahon M., Abraham A., et al. Reduced need for replacement of long term parenteral nutrition catheters following endoluminal brushing // Clin Nutr. 2015. Vol. 34, N 1. Р. 146–150. doi: 10.1016/j.clnu.2014.02.006</mixed-citation></citation-alternatives></ref></ref-list></back></article>
