Medical academic journalMedical academic journal1608-41012687-1378Eco-Vector10869010.17816/MAJ108690Conference Report, Theses of ReportCOVID-19 and its aftereffect on vestibular functionPimenovaVera M.<p>Surdologist-Otorhinolaryngologist</p>orhideya1984@mail.ruGvozdevaAlisa P.<p>Cand. Sci. (Biol.), Senior Research Associate</p>kukumalu@mail.ruhttps://orcid.org/0000-0002-7813-731XRyabkovaVarvara A.<p>Clinical Resident</p>varvara-ryabkova@yandex.ruhttps://orcid.org/0000-0001-6973-9901GavrilovaNatalia Yu.<p>MD, Cand. Sci. (Med.), Neurologist, Assistant of the Department of Faculty Therapy</p>fromrussiawithlove_nb@mail.ruhttps://orcid.org/0000-0002-2957-410XMunicipal Geriatric Medical and Social CenterSechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of SciencesAcademician I.P. Pavlov First St. Petersburg State Medical UniversitySaint Petersburg State University061120222222292341006202216082022Copyright © 2022, Eco-Vector2022<p><strong><em>BACKGROUND:</em></strong> The pandemic has led to a development of various immunological complications of COVID-19 including the chronic fatigue syndrome and fibromyalgia. These syndromes, which often manifest themselves on a background of autoimmune diseases, may develop with an entrainment of vestibular function into the pathological process.</p>
<p><strong><em>AIM:</em></strong> Aim of the study was to estimate vestibular function in groups of patients with autoimmune dysfunctions accompanied by the chronic fatigue syndrome and fibromyalgia, who have had COVID-19 and those have not had COVID-19 in their anamnesis, and to compare it with vestibular function of healthy volunteers.</p>
<p><strong><em>MATERIALS AND METHODS:</em></strong> A functional investigation of vestibular system called Vestibular passport and the anamnesis taking by a standard questionnaire were performed in patients with an implied autoimmune dysfunction and presence of the chronic fatigue syndrome, fibromyalgia and/or postural orthostatic tachycardia, and also for a control group of healthy participants.</p>
<p><strong><em>RESULTS:</em></strong> Patients who have had COVID-19 in their anamnesis demonstrated significantly higher percentage of cases of vestibulopathy than healthy volunteers (33 and 6 %, respectively). In patients without COVID-19 in their anamnesis the percentage of vestibulopathy cases did not differ significantly from the corresponding percentage in healthy volunteers (14 and 6 %, respectively). Patients complaints which indicate a vestibular pathology were confirmed in 2/3 of all cases.</p>
<p><strong><em>CONCLUSIONS:</em></strong> Patients with chronic fatigue syndrome and fibromyalgia who have had COVID-19 were more prone to vestibulopathies than patients without COVID-19 in their anamnesis, whose vestibular indices did not differ from that in healthy volunteers. The data obtained shoul be considered as preliminary.</p>COVID-19vestibulopathyautoimmune diseaseCOVID-19вестибулопатияаутоиммунное нарушение[Mohabbat AB, Mohabbat NML, Wight EC. Fibromyalgia and chronic fatigue syndrome in the age of COVID-19. Mayo Clin Proc Innov Qual Outcomes. 2020;4(6):764–766. DOI: 10.1016/j.mayocpiqo.2020.08.002][Wostyn P. COVID-19 and chronic fatigue syndrome: Is the worst yet to come? Med Hypotheses. 2021;146:110469. DOI: 10.1016/j.mehy.2020.110469][Poenaru S, Abdallah SJ, Corrales-Medina V, Cowan J. COVID-19 and post-infectious myalgic encephalomyelitis/chronic fatigue syndrome: a narrative review. Ther Adv Infect Dis. 2021;8:20499361211009385. DOI: 10.1177/20499361211009385][Amiri M, Hasanalifard M, Delphi M. Impact of COVID-19 on the auditory and vestibular system. Aud Vestib Res. 2021;30(3):152–159. DOI: 10.18502/avr.v30i3.6528][Camargo-Martínez W, Lozada-Martínez I, Escobar-Collazos A, et al. Post-COVID 19 neurological syndrome: Implications for sequelae’s treatment. J Clin Neurosci. 2021;88:219–225. DOI: 10.1016/j.jocn.2021.04.001][Wijeratne T, Crewther S. Post-COVID-19 Neurological Syndrome (PCNS); a novel syndrome with challenges for the global neurology community. J Neurol Sci. 2020;419:117179. DOI: 10.1016/j.jns.2020.117179][Garner R, Baraniuk JN. Orthostatic intolerance in chronic fatigue syndrome. J Transl Med. 2019;17(1):185. DOI: 10.1186/s12967-019-1935-y][Dolina IV, Sakovich AR. Metody issledovaniya vestibulyarnogo apparata: uchebno-metodicheskoe posobie. Minsk: BSMU; 2015. (In Russ.)][Mat Q, Noël A, Loiselet L, et al.Vestibular neuritis as clinical presentation of COVID-19. Ear Nose Throat Journ. 2021;145561321995021. DOI: 10.1177/0145561321995021][Malayala SV, Raza A. A case of COVID-19-induced vestibular neuritis. Cureus. 2020;12(6):e8918. DOI: 10.7759/cureus.8918][Gallus R, Melis A, Rizzo D, et al. Audiovestibular symptoms and sequelae in COVID-19 patients. J Vestib Res. 2021;31(5):381–387. DOI: 10.3233/VES-201505]