EFFICIENCY OF COMPLEX THERAPY IN ACUTE PERIPROCTITIS

Aim. To study the efficiency of ozonotherapy and antioxidant/antihypoxant remaxol in complex treatment of acute periproctitis. Materials and methods. The work is based on clinical observation of patients with acute purulent periproctitis ( n =46) divided into two groups. In the control group ( n =26), patients with periproctitis received basic (antibiotics, detoxicants, anti-inflammatory, antihistaminic and other drugs) therapy, in the main group – this therapy was added by intravenous introduction of 0,89% ozonized isotonic sodium chloride solution. Results. It was stated by clinicolaboratory investigations that complex treatment of acute periproctitis including ozonotherapy and remaxol in the early postoperative period significantly heightened the efficiency of treatment that was proved by positive dynamics of some clinical and laboratory parameters. The ability of ozonotherapy to reduce an alternative phenomena, to raise reparative potential of tissue structures at the expense of improvement of microcirculation in the damaged tissue wound structures is an important mechanism for realizing medical effects. Conclusion. Application of complex therapy resulted in correction of a number of homeostatic indices of the body. Essential decrease in manifestation of endogenous intoxication syndrome and rapid restoration of functional erythrocyte status was proved.

Periproctitis, ozonotherapy, remaxol, endogenous intoxication, erythrocytes