Arterial stiffness in young patients with chronic glomerulonephritis

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Abstract


Aim. To study the presence of the phenomenon of stiffness of the arterial vessels in young patients with chronic glomerulonephritis.

Materials and methods. The parameters of malleolar-brachial index (while chronic kidney disease (CKD) progression) were studied in 47 young patients with chronic glomerulonephritis and 24 comparable by age healthy volunteers.

Results. There was detected the elevation of malleolar-brachial index in young patients with chronic glomerulonephritis, when having stage 3-5 CKD.

Conclusions. Malleolar-brachial index, as an index of arterial stiffness, grows with CKD progression, that is a marker of early aging of vessels and cardiovascular remodeling in young patients with chronic glomerulonephritis.


A. V. Khachatryan

Author for correspondence.
khachatryan.armenui@mail.ru
Academician Ye.A. Vagner Perm State Medical University
Russian Federation, 26, Petropavlovskay street, Perm, 614000

аспирант кафедры госпитальной терапии

L. N. Nekrutenko

khachatryan.armenui@mail.ru
Academician Ye.A. Vagner Perm State Medical University
Russian Federation, 26, Petropavlovskay street, Perm, 614000

доктор медицинских наук, профессор кафедры госпитальной терапии

L. M. Vasilets

khachatryan.armenui@mail.ru
Academician Ye.A. Vagner Perm State Medical University
Russian Federation, 26, Petropavlovskay street, Perm, 614000

доктор медицинских наук, профессор кафедры госпитальной терапии

  • Диагностика и коррекция нарушений липидного обмена с целью профилактики и лечения атеросклероза. Российские рекомендации, VI пересмотр. М. 2017, available at: http://webmed.irkutsk.ru/doc/pdf/noa.pdf
  • Кобалава Ж.Д., Котовская Ю.В., Виллевальде С.В., Соловьева А.Е., Амирбегишвили И.М. Артериальная жесткость и ХБП: причины и последствия. Рациональная фармакотерапия в кардиологии 2014; 10 (1): 83–84.
  • Милованова Л.Ю., Милованов Ю.С., Козловская Л.В. Нарушения фосфорно-кальциевого обмена при хронической болезни почек III–V стадий. Клиническая нефрология 2011; 1: 58–68.
  • Рогоза А.Н. Роль и возможности лодыжечно-плечевого индекса систолического давления при профилактических обследованиях. РМЖ 2011; 4: 173.
  • Туев А.В., Некрутенко Л.А. Артериальная гипертензия: проблемы тромбофилии, эндотелиальная дисфункция, метаболическое обеспечение, оптимизация лечения. Под ред. А. Зебзеевой. М.: Здравствуй 2001; 50–57.
  • Boutouyrie P., Fliser D., Goldsmith D. Assessment of arterial stiffness for clinical and epidemiological studies: methodological considerations for validation and entry into the European Renal and Cardiovascular Medicine registry. Nephrol Dial Transplant 2013; 29 (2): 1–9.
  • Coresh J., Selvin E., Stevens L. Prevalence of chronic kidney disease in the United States. JAMA 2007; 298: 2038–2047.
  • Iseki K., Fukiyama K. Predictors of stroke in patients receiving chronic hemodialysis. Kidney Int 1996; 50: 1672–1675.
  • Onoyama K., Kumagai H., Miishima T., Tsuruda H., Tomooka S., Motomura K., Fujishima M. Incidence of strokes and its prognosis in patients on maintenance hemodialysis. Jpn Heart J 1986; 27: 685–691.
  • United States renal data system. Annual data report 2006. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases 2006.
  • 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2010; 56 (25): 2182–2199.
  • 2017 Hypertension guideline data supplements (Section numbers correspond to the full-text guideline). American College of Cardiology Foundation and the American Heart Association, Inc. 2017: available at http:// jaccjacc.acc.org/Clinical_Document/2017_HBP_FT_DATA_SUPPLEMENT.pdf

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