Pharmacy Formulas
https://journals.eco-vector.com/PharmForm
<p><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Медицинский и биологический рецензируемый журнал. </span></span><br /><strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Главный редактор</span></span></strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> : д.м.н., профессор Перелыгин Владимир </span></span><br /><strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Индексирование</span></span></strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> : Google Scholar, WorldCat, РИНЦ </span></span><br /><strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">ISSN</span></span></strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> : (Печать); </span></span><strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">ISSN</span></span></strong><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> : (онлайн)</span></span></p> <p> </p>
NWI MBP EP
ru-RU
Pharmacy Formulas
2713-153X
<p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal exclusive license to first publication.</li> <li>Authors are able to distribute the manuscript and/or the article in accordance with Self-Archiving policy of the journal (<a href="/PharmForm/about/editorialPolicies#authorSelfArchivePolicy" target="_blank" rel="noopener">see details</a>).</li> <li>The manuscript can be accepted for publication only by decision of the Editor-in-Chief and the Editorial board of the journal in accordance with the Manuscript stelection policy of the journal (<a href="/PharmForm/about/editorialPolicies#peerReviewProcess" target="_blank" rel="noopener">see details</a>).</li> <li>Published Article will be distributed in print and electronic version an will be available under subscription with Delayed Open Access or in Immediate Open Access under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (<a href="https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ru" target="_blank" rel="noopener">CC BY-NC-ND 4.0</a>). The access model depends on the publisher's decision or is determined by a separate Open Access publishing agreement with the authors.</li> </ol> <p>An exclusive license for publication granted by authors allows the publisher to use the article in the following ways:</p> <ul> <li>Reproduction of the Article or its sections or parts, as well as the metadata of the Article in any languages, in any material form, including on paper and electronic media, as a separate work in the journal and/or databases (local or in the Internet) of the publisher and/or other persons, at the discretion of the publisher;</li> <li>Distribution of the Article or its sections or parts, as well as the metadata of the Article in any languages, on any medium as part of the journal and/or databases of the publisher or other persons, at the discretion of the publisher, or as an independent work around the world whether on Open-Access terms or for a fee without remuneration to the Author;</li> <li>Making the Article or any of its sections or parts, as well as the Article’s metadata in any languages, publicly available in such a way that any person can access the Article from any place, including via the Internet, and at any time of their own choosing;</li> <li>Granting permission/s for the use of the Article or its sections or parts, as well as its metadata in any languages, to third parties with notice to the Author made by posting relevant information on the journal’s website, without paying remuneration to the Author;</li> <li>Processing the Article (i.e., editing, correcting, annotating, tagging, translating to any languages, typesetting) and using the revised (translated) Article in the aforementioned ways.</li> </ul> <p>Other rights not directly transferred to the publisher under this License Agreement, including patent rights to any process, method etc., described by the Authors in the manuscript, as well as trademark rights, are reserved for the Authors.</p> <p>All the Copyright statements for authors are present in the standart Publishing Agreement (Public Offer) to Publish an Article in an Academic Periodical <strong>'Pharmacy Formulas'</strong>.</p> <p>- <a href="/files/journals/58/doc/Copyrightagreement_final_eng_exclusive_v.2022.09.29.pdf" target="_blank" rel="noopener">DOWNLOAD</a> the print-version of the License Agreement.</p> <div><details> <summary><strong>READ the details online</strong> (tap to see in details)</summary> <p><strong>Author’s license agreement (public offer) on the publication of an article in a scholarly journal </strong><br />“<strong>Pharmacy Formulas</strong>”</p> <p>Eco-Vector, represented by its CEO Evgeniy Schepin and acting on the basis of the Charter (hereinafter referred to as the Publisher), on the one hand, offers an indefinite circle of persons (hereinafter referred to as the Author), and on the other hand, hereinafter jointly referred to as the Parties, to execute this agreement (hereinafter referred to as the Agreement) on the publication of scientific article (hereinafter referred to as the Article) in a scholarly journal “<strong>Pharmacy Formulas</strong>” (further-the Journal) in accordance with the conditions stated below.</p> <p> </p> <p><strong>I. General Provisions</strong></p> <ol> <li>This Agreement, in accordance with clause 2 of Article 437 of the Civil Code of the Russian Federation, is a public offer (hereinafter referred to as the Offer) requiring full and unconditional acceptance (Acceptance), which, in accordance with Article 438 of the Civil Code of the Russian Federation, means the sending by the Author of his/her materials by way of uploading the same to the online electronic system designed to accept manuscripts for consideration, and subsequently posted in the corresponding section of the Journal’s website on the Internet information and telecommunications network (hereinafter referred to as the Internet).</li> <li>In accordance with the current legislation of the Russian Federation regarding the observance of copyright on electronic information resources, all materials found in a website, including submitted and published in electronic journals, may not be reproduced in whole or in part in any form (electronic or printed) without the prior written permission of the Publisher. Prior permission can be given by publishing an article in the open access with Creative Commons license. The journal requires license users to reference the original source, i.e., the publication, if the Author permits use of the public materials in the context of other documents.</li> </ol> <p> </p> <p><strong>II. Terms used in the Agreement</strong></p> <ol> <li>“Author” refers to an individual (or individuals) whose creative work has led to the creation of the manuscript of a scientific Article, or to a representative of these persons.</li> <li>“Manuscript” is the result of intellectual activity in the form of a scientific work containing text, graphic and numerical data, audiovisual information, program code and other elements submitted by the Author for publication in the Journal; it is also the mean “a draft of an Article submitted by the Author to be published in the Journal”.</li> <li>“Offer” is the current agreement (an offer to the author for the publication of an Article in the Journal).</li> <li>“Publication” is the process of placement of an Article in the Journal.</li> <li>“Article” is the manuscript that has been published in the Journal (after successful selection, editing, type-setting, copyediting, proofreading, translation).</li> <li>“Acceptance of the offer” refers to the full and unconditional acceptance of the offer on the terms specified in paragraph 3 of this agreement (the Author accepts offer by submitting a Manuscript to the Publisher via the online electronic submission system on the Journal’s Internet website).</li> <li>“Journal” is a scientific peer-reviewed periodical registered as a mass media entity in the Roskomnadzor register of the Russian Federation and ISSN-center.</li> <li>“Submission” is an electronic appeal of the Author to the Publisher for the publication of an Article in the Journal by uploading the manuscript and accompanying materials to the online electronic submission system on the Journal’s Internet website).</li> <li>“Publisher” refers to Eco-Vector, which is the Publisher of the journal.</li> <li>Article metadata includes the information that are intended for inclusion in International Scientific Databases and search engines, namely the following: <ul> <li>title of the Article;</li> <li>information about each of the Authors (surname and first name; patronymic; place of work with the postal address indicated, contact information (e-mail));</li> <li>abstract;</li> <li>keywords;</li> <li>thematic rubricator: UDC (Universal Decimal Classification) or other library and bibliographic classification and subject indexes;</li> <li>list of references.</li> </ul> </li> <li>“Editorial board” is the creative team that prepares the journal for publication.</li> <li>“Parties” refers to the Author and the Publisher.</li> <li>“Author Guidelines” are the requirements for Articles published in the Journal, posted in the “For authors” section of the Journal’s Internet website.</li> </ol> <p> </p> <p><strong>III. Subject of the Agreement (Offer)</strong></p> <ol> <li>Under this agreement, the Author grants the Publisher, free of charge for the entire period of validity in accordance with the legislation of the Russian Federation, an exclusive license to use the Article created by the former for publication in the Journal, as well as the rights to use the article in the following ways: <ul> <li>Reproduction of the Article or its sections or parts, as well as the metadata of the Article in any languages, in any material form, including on paper and electronic media, as a separate work in Journals and/or databases (local or in the Internet) of the Publisher and/or other persons, at the discretion of the Publisher;</li> <li>Distribution of the Article or its sections or parts, as well as the metadata of the Article in any languages, on any medium as part of the Journal and/or databases of the Publisher or other persons, at the discretion of the Publisher, or as an independent work around the world whether on Open-Access terms or for a fee without remuneration to the Author;</li> <li>Making the Article or any of its sections or parts, as well as the Article’s metadata in any languages, publicly available in such a way that any person can access the Article from any place, including via the Internet, and at any time of their own choosing;</li> <li>Granting permission/s for the use of the Article or its sections or parts, as well as its metadata in any languages, to third parties with notice to the Author made by posting relevant information on the Journal’s website, without paying remuneration to the Author;</li> <li>Processing the Article (i.e., editing, correcting, annotating, tagging, translating to any languages, typesetting) and using the revised (translated) Article in the aforementioned ways.</li> </ul> </li> <li>Other rights not directly transferred to the Publisher under this Agreement, including patent rights to any process, method etc., described by the Author in the Article, as well as trademark rights, are reserved for the Author.</li> <li>The territory where the rights to the Article are allowed to be used is the whole world.</li> <li>The validity of this Agreement commences only if the manuscript of the Article is accepted for publication in the Journal and only from the moment of sending a notification of acceptance of the Article for publication to the Author from the official e-mail of the Journal.</li> <li>The rights are granted by the Author to the Publisher free of charge; the publication of the Article in the Journal does not entail any financial deductions to the Author.</li> <li>If the Publisher decides to reject the Submission or refuse to publish the Article in the Journal (i.e., retraction of the published Article), this Agreement becomes invalid. The decision to refuse publication will be sent to the Author at the e-mail address specified in the Submission.</li> </ol> <p> </p> <p><strong>IV. Rights and Duties of the Parties</strong></p> <ol> <li>The Author guarantees that: <ul> <li>s/he holds the copyright the exclusive rights to the materials submitted to the Publisher as part of the manuscript of the Article;</li> <li>the rights granted to the Publisher under this agreement have not been previously transferred and will not be transferred to third parties in the future during the duration of the Agreement;</li> <li>the manuscript contains all references to the cited authors and/or publications (materials) provided for under the current copyright legislation;</li> <li>the Author has obtained all the necessary permissions for all information and other materials s/he holds no copyright to and that are used in the manuscript of the Article;</li> <li>the Article manuscript contains only materials permitted to be published in the open press in accordance with the current legislative acts of the Russian Federation, and its publication and distribution will not lead to the disclosure of secret (confidential) information (including state secrets);</li> <li>the Author has informed co-authors about the terms of this Agreement and has received their consent to execute this Agreement under the terms provided for in the Agreement.</li> </ul> </li> <li>The Author carries certain obligations under the terms of the Agreement: <ul> <li>s/he should prepare and submit the manuscript of the Article in accordance with the Author Guidelines posted on the Journal’s website;</li> <li>the Author should not use an electronic copy of the Article for commercial purposes and in other journal publications without the consent of the Publisher;</li> </ul> </li> <li>in the process of preparing a manuscript for publication, the Author is obligated to undertake the following: <ul> <li>make corrections to the text of the manuscript that have been marked by the peer-reviewers and accepted by the editorial board, and/or as necessary, upon the request of the Publisher and the editorial board, finalize the manuscript of the Article;</li> <li>revising and proofreading the manuscript of the Article in accordance with the editorial recommendations;</li> <li>suggest only the minimum of corrections to the type-setted (layout) Article.</li> </ul> </li> <li>The Author has the following rights and duties: <ul> <li>Use preprint or prior-to publication versions of an unpublished Article in the form and content accepted by the Publisher for publication in the Journal. Such prior-to-publish versions can be placed as electronic files on the personal websites of the Author (co-authors) or on the protected external websites of the employers of the Author; however, the Author cannot use the unpublished version(s) for commercial sale or for systematic external distribution by a third party (i.e., post on social media). The author or co-authors must, in turn, carry out certain duties, namely: <ul> <li>include the following warning in the prior-to-publish version: “This is prior-to-publish version of the article accepted for publication in (Journal’s name), © Eco-Vector (year)”;</li> <li>provide the corresponding electronic link to the Publisher’s website at <a href="https://journals.eco-vector.com/">https://journals.eco-vector.com/</a> and/or via the DOI.</li> </ul> </li> <li>Copy or transfer a copy of the published Article in whole or in part to colleagues free of charge for their personal or professional use, for the promotion of academic or scientific research, or for informational purposes of the Author’s employer.</li> <li>Use materials from a published Article in a book written by one of the co-authors.</li> <li>Use figures, tables and text excerpts from the Article for his or her (or co-authors’) own training purposes, or to include them in other published works in printed or electronic format by a third party, or to submit them in electronic format on an internal computer network, or on the public website of the Author (co-authors) or his/her employer.</li> <li>Include the Article in educational collections for use in the classroom, either for free distribution to the Author’s (co-authors’) students or in electronic format on a local server for access by students as part of the training course, as well as for internal training programs at the institution of the Author’s employer.</li> </ul> </li> <li>The Publisher, for its part, is obliged to: <ul> <li>publish the Author’s article in the Journal in printed and electronic form in accordance with the terms of this Agreement;</li> <li>if necessary, as so decided by the Journal’s editorial board, provide the Author with the proofreading of the manuscript and make a reasonable editing;</li> <li>provide to the Author the unlimited access to the final electronic version of the published Article (Version of Record) through the online electronic submission system on the Journal’s Internet website;</li> <li>comply with the Author’s rights as provided for by the current legislation, as well as protect them and take all necessary measures to prevent copyright infringement by third parties.</li> </ul> </li> <li>The Publisher has a right to: <ul> <li>conduct an expert evaluation of the manuscript (peer-reviewing and editorial evaluation) and invite the Author to make the necessary changes (revisions) to the manuscript;</li> <li>provide editing, copyediting, type-setting, proofreading, tagging, indexation and translation of the Article’s manuscript without altering the main content;</li> <li>in any subsequent authorized use by the Author (and/or other persons) of the Journal and/or Article (including any separate part or fragment thereof), require that a link to the Journal, Publisher, Author or other copyright holders, the title of the Article, the Journal’s volume/issue, and the year of publication be specified in the Journal;</li> <li>post preliminary and/or advertising information about the upcoming publication of the Article in the media and other information sources;</li> <li>make changes to the offer in accordance with the procedure established by the offer.</li> </ul> </li> <li>The editorial board of the Journal, headed by the editor-in-chief, has the exclusive rights to select and/or reject materials sent to the Journal editorial office for publications purposes. The manuscript sent by the Author to the Journal editorial office is not subject to return. The editorial board of the Journal does not enter into correspondence about rejection of submissions.</li> <li>In all cases not stipulated and not provided for in this agreement, the parties are obliged to be guided by the relevant current laws of the Russian Federation.</li> </ol> <p> </p> <p><strong>V. Acceptance of the Offer and Execution of the Agreement. Terms of the Agreement</strong></p> <ol> <li>The Author accepts the Offer by submitting the manuscript on the Article to the Publisher through the electronic manuscript submission system on the Journal's Internet website.</li> <li>Acceptance of the offer by the author creates an Agreement in writing (Articles 438 and 1286.1 of the Civil Code of the Russian Federation) on the terms of the offer.</li> <li>This Agreement is valid for the duration of the exclusive rights to the Article.</li> <li>When transferring (alienating) the exclusive right to the Article by the Author to a third party, this Agreement does not terminate.</li> </ol> <p> </p> <p><strong>VI. Procedure for changing and terminating the Agreement</strong></p> <ol> <li>The Publisher has the right to unilaterally change the terms of this Agreement, in advance, at least 10 (ten) calendar days before the entry into force of the intended relevant changes, but with notice to the Author through the Journal’s website or by e-mail to the Author’s e-mail address specified in the Author’s Submission. The changes will take effect from the date specified in the relevant notification.</li> <li>If the Author rejects the changes to the terms of this Agreement, s/he has the right to notify the Publisher by sending a written notification through the online manuscripts submission system, making sure that the same is sent to the official e-mail address of the editorial office.</li> <li>This Agreement may be terminated prematurely, either by agreement of the parties at any time, or on other grounds provided for in this Agreement.</li> <li>The Author has the right to unilaterally withdraw from the execution of this Agreement by sending the Publisher a corresponding notification in writing at least 60 (sixty) calendar days in advance before the expected date of publication of the Article in the Journal.</li> <li>Termination of the Agreement for any reason does not release the parties from liability for any violation of the terms of the Agreement that occurred during the validity period.</li> </ol> <p> </p> <p><strong>VII. Responsibility</strong></p> <ol> <li>The parties are responsible for non-fulfillment or improper fulfillment of their obligations under the Agreement in accordance with the current relevant legislation of the Russian Federation.</li> <li>All information provided by the Author must be reliable. The Author is expected to provide accurate and complete the information to the Publisher. When using false information received from the Author, the Publisher is not responsible for the negative consequences caused by his actions on the basis of the false information provided.</li> <li>With regard to the content of the Article, the Author is solely responsible for compliance with the requirements of the laws of the Russian Federation pertaining to advertising, copyright and related rights’ protection, protection of trademarks and service marks, and the protection of consumer rights.</li> <li>The Publisher does not bear any responsibility under the agreement: <ul> <li>for any actions that are a direct or indirect result of Author’s illegal actions;</li> <li>for any loss incurred by the Author, regardless of whether the Publisher could have foreseen the possibility of such losses or not.</li> </ul> </li> <li>The Publisher is released from liability for violation of the terms of the Agreement if such violation is caused by force majeure, including actions of state authorities (including the adoption of legal acts), fire, flood, earthquake, other natural disasters, lack of electricity and/or computer network failures, strikes, civil unrest, riots, etc.</li> </ol> <p> </p> <p><strong>VIII. Dispute resolution</strong></p> <ol> <li>Disputes and disagreements will be resolved by the parties through negotiations, and in case of failure to reach an Agreement they will strive to seek resolution in accordance with the current legislation of the Russian Federation.</li> <li>If there are unresolved disagreements, the parties agree to resolve the disputes in court at the jurisdiction covered by the Publisher’s location in accordance with the current legislation of the Russian Federation.</li> </ol> <p> </p> <p><strong>IX. Miscellaneous</strong></p> <ol> <li>All notifications, messages, requests, etc. (with the exception of documents that must be sent as originals in accordance with the laws of the Russian Federation) are considered received by the Author if they were transmitted (sent) by the Publisher through the Journal’s website (including by publication), fax, e-mail based on the address specified in the Submission, and other communication channels. The parties recognize the legal force of notifications, messages, requests, etc., transmitted (sent) by the above methods.</li> <li>In the event of claims against the Publisher related to the violation of the exclusive copyright and other intellectual property rights of third parties when creating an article or in connection with the execution of this Agreement by the Author, as well as in connection with the use of the Article by the Publisher in accordance with the Agreement, the author undertakes: <ul> <li>To immediately take measures to resolve disputes with third parties soon after receiving Publisher’s notification, and if necessary, enter into legal proceedings on the Publisher’s side and take all appropriate actions needed to exclude the Publisher from the list of defendants;</li> <li>To reimburse the publisher for the legal costs incurred and expenses and losses caused by the application of measures to secure the claim and execute a court decision, and the money paid to a third party for the violation of exclusive copyright and other intellectual property rights, as well as other losses incurred by the Publisher in connection with the Author’s non-compliance with the guarantees provided by them under this Agreement.</li> </ul> </li> </ol> <p> </p> <p><strong>X. Legal address and details of the Publisher</strong></p> <ul> <li>Eco-Vector</li> <li>Address: 191186, St. Petersburg, Aptekarsky Pereulok, 3 letter A, room 1N</li> <li>TIN: 7806423692; KPP: 784101001; OGRN: 1099847039907.</li> </ul> </details></div>
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The antiarrhythmic activity of amino acid-containing derivatives of 1,4-naphthoquinone
https://journals.eco-vector.com/PharmForm/article/view/626911
<p style="text-align: justify;">In recent times, the issue of cardiac arrhythmia disturbances has garnered increasing attention from researchers. Pharmacotherapy continues to be the primary method for treating rhythm disturbances; however, its effectiveness is often limited due to the common side effects associated with many antiarrhythmic drugs, among which negative inotropic action plays a significant role. One direction in the development of antiarrhythmic agents involves the targeted search for new drugs among agents with metabolic effects. The aim of this study was to investigate the antiarrhythmic activity using models of occlusion and reperfusion arrhythmias in cats, aconitine arrhythmias in rats, and calcium chloride ventricular fibrillation in rats of five original amino acid-containing derivatives of 1,4-naphthoquinone, synthesized at the Lviv Polytechnic Institute under the guidance of Ph.D. A.P. Kartoflitska. The conducted research indicated that the studied compounds exhibit antiarrhythmic effects. The enhancement of the antiarrhythmic activity occurred primarily in those arrhythmia models where metabolic disorders play a significant role in the pathogenesis.</p>
Svetlana M. Napalkova
Olga V. Buyuklinskaya
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
10
15
10.17816/phf626911
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The state of cancer care in Russia: age and cancer. Features of the localization structure, quality of accounting and survival of patients with malignant neoplasms of senile age and centenarians (population study). Part 5
https://journals.eco-vector.com/PharmForm/article/view/625693
<p style="text-align: justify;">In accordance with the World Health Organization (WHO) standard, the elderly population is defined as individuals aged 75 to 89, while long-livers are those aged 90 and older. According to the United Nations, long-livers are individuals who have reached 100 years of age. In the preceding four messages, we explored the specific detailed localization structure of morbidity, mortality, and survival in pediatric, adolescent, young adult, middle-aged, and elderly populations. However, the analysis of these characteristics for individuals in the elderly and long-liver categories is conducted for the first time. Old age is the period of human life characterized by the loss of the body's ability to sustain the species, deterioration of mental capacities, and decline in bodily functions. It represents an age range for individuals nearing the expected life span. Gerontologists are concerned with medical research into the aging process, while diseases affecting the elderly and old age fall under the purview of geriatrics. The discipline of gerontology deals with the technologies for supporting an aging society. The elderly and older adult populations are more susceptible to diseases and injuries. They face economic challenges related to retirement, loneliness, and ageism – age-based discrimination. The WHO's definition of "elderly" encompasses three five-year age groups, including long-livers: - 75-79 years – early old age - 80-84 years – advanced old age - 85-89 years – late old age - 90 years and older – long-livers. We will attempt to examine the specific localization characteristics and the potential effectiveness of specialized oncological care for each of these age groups. Emphasis will also be placed on the quality of primary patient registration whenever possible.</p>
Vakhtang M. Merabishvili
Anna O. Shakhzadova
Vladimir V. Perelygin
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
16
32
10.17816/phf625693
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Glucans and heteroglycans of fungi and their potential in cancer immunotherapy
https://journals.eco-vector.com/PharmForm/article/view/625415
<p style="text-align: justify;">The present review is devoted to the oncostatic properties of glucans and heteroglycans produced by higher fungi. These are the most pharmacologically promising substances, since they are produced in large quantities both by artificially grown mycelium and fruiting bodies, do not require complex purification methods, are devoid of toxicity, and, having a complex (immune-mediated and direct) effect on tumors, do not require any complex fractionation procedures. The diversity of β-glucans produced by fungi is shown, the main types of these macromolecules are considered (according to the structural features of the macromolecule, the linear and branched forms of β-glucans are distinguished, first of all). Heteroglycans, a more diverse but less studied group of fungal compounds, have also been characterized. The effects of fungal β-glucans and heteroglycans on immune and cancer cells described in the literature are considered. The long and branched chains of these biopolymers, as well as peptides and lipids covalently bound to them, have fragments that are complementary to the binding sites of the surface receptors of the animal cell and thus act as their agonists or antagonists. They are recognized by the receptors of antigen-representing cells of the immune system as pathogen-associated molecular patterns, what leads to the activation of the cytotoxic component of the immune system; to reduce their tolerogenic and immunosuppressive signaling. Prospects for further study of fungal glucans and heteroglycans are outlined.</p>
Ivan V. Zmitrovich
Vladimir V. Perelygin
Mikhail V. Zharikov
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
34
45
10.17816/phf625415
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The influence of short-term heating on the activity of amylolytic enzymes in honey
https://journals.eco-vector.com/PharmForm/article/view/624477
<p style="text-align: left;">This study presents the results of the analysis of the activity of amylolytic enzymes in honey, depending on short-term heating, simulating the process of adding honey to hot tea. Additionally, a comparison of this activity with similar enzymes present in the pharmaceutical preparation "Festal" was conducted. Regularities in the change of amylolytic enzyme activity were established, contributing to the development of recommendations for honey consumption considering this parameter. The obtained results demonstrate significantly lower activity of amylolytic enzymes in honey compared to the pharmaceutical preparation. However, considering differences in consumption, it is possible to assess them as comparable. It was also revealed that the activity of amylolytic enzymes in honey changes during short-term heating, not decreasing until the temperature reaches 30°C. Based on the in vitro activity analysis, the tested sample corresponds to the pharmaceutical preparation "Festal," allowing for prospects for further research into the impact of honey's amylolytic enzymes on the human body, requiring more precise methods of study. </p>
Varvara V. Solovyova
Vyacheslav A. Tikhomirov
Ksenia A. Filatova
Sergey G. Paramonov
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
46
51
10.17816/phf624477
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Microbiological studies of juniper extract to determine sensitivity to strains of microorganisms
https://journals.eco-vector.com/PharmForm/article/view/625348
<p style="text-align: justify;">Juniper is a widely used resource in the food, cosmetic, and medical industries. However, its application in veterinary medicine represents a less researched area. Literature studies confirm the presence of terpenoid compounds, tannins, ketones, sugars, organic acids, and flavonoids in juniper. Determination of the chemical composition of juniper essential oil revealed the prevalence of terpenes such as α-pinene, β-pinene, ocimene, and α-limonene, with variations depending on the species and habitat of the plant. Analysis of the literature data highlights the significant importance of α-pinene, serving as the primary and most studied terpene in juniper essential oil with notable diuretic properties. Furthermore, juniper essential oil possesses antibacterial, antifungal, anti-inflammatory, and deodorizing properties. The aim of the study was to reassess the antimicrobial and antifungal properties of the extract obtained from common juniper fruits through extraction. The research used extracts of essential oils obtained from common juniper fruits and tested them for antibiotic activity against microorganisms of various taxonomic groups. The experiment was conducted in accordance with sanitary and epidemiological requirements and federal clinical recommendations. The research methodology included serial dilutions, preparation of microbial suspensions, inoculation of nutrient media, incubation, and result assessment. </p>
Karina O. Ivanova
Alexander M. Lunegov
Tatiana F. Chernykh
Konstantin F. Zenkov
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
52
56
10.17816/phf625348
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Life path of Leonid Vasilyevich Dmitrenko
https://journals.eco-vector.com/PharmForm/article/view/625524
<p>The essay is dedicated to Leonid Vasilyevich Dmitrenko, a Soviet and Russian scientist and specialist in the field of chemical physics, whose scientific, pedagogical, and organizational activities unquestionably laid the foundation for further development in the area of high-molecular compounds and their industrial production. Leonid Vasilyevich was an outstanding scientist and researcher, distinguished by his intellectualism, kind attitude towards colleagues and students, and his concern for people's problems, providing invaluable assistance and support to those in need. Bright memories of Leonid Vasilyevich will forever remain in the hearts and minds of his relatives, coworkers, and students and graduates of the university. This essay is written with the support of Leonid Vasilyevich's daughter, Julia Leonidovna Berdnikova, who was able to provide materials from her family's archives.</p>
Natalya V. Glazova
Yulia L. Berdnikova
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
62
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10.17816/phf625524
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Half a Century in Service: Professor Leonid Gerasimovich Marchenko (1941–2019)
https://journals.eco-vector.com/PharmForm/article/view/625824
<p>This text is a dedication to the Professor Leonid Gerasimovich Marchenko, a graduate of the Leningrad Institute of Chemical-Pharmaceutical Sciences. Throughout his career in education, L.G. Marchenko progressed from being an assistant to eventually heading the Department of Pharmaceutical Technology of Medications. Apart from his teaching activities, he was actively involved in administrative work: serving as deputy dean, and from 1983 to 1986, as the dean of the Pharmaceutical Faculty; from 1986 to 2005, he was the Vice-Rector for Academic Affairs, then from 2005 to 2008, the First Vice-Rector for Academic Affairs, and from 2008 to 2009, an advisor to the rector. The essay draws on family archival materials, thanks to the active support of Ekaterina Anatolievna Marchenko, who carefully preserves the memory of her husband, L.G. Marchenko. For almost half a century, Leonid Gerasimovich's life was inseparably linked to the Saint Petersburg State Chemical-Pharmaceutical University. Here he studied from his student years, continued his education in graduate school, and then worked in the university for more than 40 years. Leonid Gerasimovich embodied the principles of academic integrity and responsibility. He always attached great importance to the quality of his work, sought perfection, and inspired his colleagues to achieve high results.</p>
Elena V. Flisyuk
Alexey L. Marchenko
Copyright (c) 2023 Eco-Vector
https://creativecommons.org/licenses/by-nc-nd/4.0
2023-12-20
2023-12-20
5 4
70
75
10.17816/phf625824