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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Family Doctor</journal-id><journal-title-group><journal-title xml:lang="en">Russian Family Doctor</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский семейный врач</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2072-1668</issn><issn publication-format="electronic">2713-2331</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1428</article-id><article-id pub-id-type="doi">10.17816/RFD2013244-47</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">CASE FROM PRACTICE: THE CASE OF DRUG ALLERGY MANIFESTED BY SELECTIVE NEUTROPENIA COMBINED WITH FIXED TOXICODERMIA SYNDROME</article-title><trans-title-group xml:lang="ru"><trans-title>СЛУЧАЙ ЛЕКАРСТВЕННОЙ АЛЛЕРГИИ, ПРОЯВИВШЕЙСЯ СЕЛЕКТИВНОЙ НЕЙТРОПЕНИЕЙ В СОЧЕТАНИИ С СИНДРОМОМ ФИКСИРОВАННОЙ ТОКСИДЕРМИИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kiseleva</surname><given-names>G V</given-names></name><name xml:lang="ru"><surname>Киселева</surname><given-names>Г В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">North-Western State Medical University named after I. I. Mechnikov</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Северо-Западный государственный медицинский университет имени И. И. Мечникова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2013</year></pub-date><volume>17</volume><issue>2</issue><issue-title xml:lang="en">VOL 17, NO2 (2013)</issue-title><issue-title xml:lang="ru">ТОМ 17, №2 (2013)</issue-title><fpage>44</fpage><lpage>47</lpage><history><date date-type="received" iso-8601-date="2016-03-16"><day>16</day><month>03</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Kiseleva G.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Киселева Г.В.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Kiseleva G.V.</copyright-holder><copyright-holder xml:lang="ru">Киселева Г.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/RFD/article/view/1428">https://journals.eco-vector.com/RFD/article/view/1428</self-uri><abstract xml:lang="en"><p>The article presents the observation of drug allergy manifested by selective neutropenia combined with fixed toxicodermia syndrome as result of treatment by drug nurofen at a boy of 10 years old</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлено наблюдение случая лекарственной аллергии по типу селективной нейтропе-нии в сочетании с синдромом фиксированной токсидермии вследствие приема препарата «Нурофен» у ребенка 10 лет</p></trans-abstract><kwd-group xml:lang="en"><kwd>nurofen</kwd><kwd>drug allergy</kwd><kwd>selective neutropenia</kwd><kwd>fixed toxicodermia syndrome</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нурофен</kwd><kwd>лекарственная аллергия</kwd><kwd>селективная нейтропения</kwd><kwd>фиксированная ток-сидермия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Таболин В. А., Османов И. М., Длин В. В. Применение жаропонижающих средств в детском возрасте // Клин. фармакология и терапия. — 2002. — Т. 11. — № 5. — С. 12-14.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Балабанова Р. М., Запрягаева М. Е. Безопасность ибупрофена в клинической практике // РМЖ. — 2003. — Т. 11. — № 22. — С. 1216-1219.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>McGettigan P., Henry D. Cardiovascular Risk with Non-Steroidal Anti-Inflammatory Drugs: Systematic Review of Population-Based Controlled Observational Studies. PLoS Med. — 2011. — P. 63-65.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Исаков В. А. Как определить степень риска у пациента, принимающего НПВП, выбрать алгоритм его ведения? // Гастроэнтерология. — 2006. — № 2. — C. 13-16.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Hillis W. S. Areas of emerging interest in analgesia: cardiovascular complications // Amer. J. of Therapeutics. — 2002. — Vol. 9. — P. 259-269.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Gooch K., Culleton B. F., Manns B. J. et al. NSAID use and progression of chronic kidney disease // Am. J. Med. — 2007. — № 3. — P. 1-7.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Beijer H. J., de Blaey C. J. Hospitalizations caused by adverse drug reactions (ADR): A meta-analysis of observational studies // Pharmacy World and Science. — 2002. — № 24. — P. 46-54.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Schiller J. S., Lucas J. W., Ward B. W., Peregory J. A. Division of Health Interview Statistics // Summary Health Statistics for U. S. Adults: National Health Interview Survey. — 2010. — P. 52-54.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Paediatric Intensive Care Pharmacists' Special Interest Group. Neonatal and Paediatric Pharmacists group. PIC SIG NPPG. — NPPG October 2011. — 42 p. — http://nppg.org.uk. — Последнее посещение сайта 01.04.2013 г.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>McKenna J. K, Leiferman K. M. Dermatologic drug reactions // Immunol. Allergy Clin. North Am. — 2004. — P. 399-423.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Celik G., Pichler W. J., Adkinson N. F. Jr. Drug Allergy. In Adkinson N. F. Jr., ed. Middleton's Allergy: Principles and Practice. 7th ed. // Philadelphia, Pa; Mosby Elsevier. — 2008. — 68 p.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Зайчик А. Ш., Чурилов Л. П. Общая патофизиология (с основами иммунопатологии). Книга 1-я. (Учебник для студентов медицинских вузов.) Изд. 4-е. — СПб.: ЭЛБИ-СПб, 2008. — 656 с.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Andres E., Federici L., Weitten T. et al. Recognition and management of drug-induced blood cytopenias: the example of drug-induced acute neutropenia and agranulocytosis // Expert. Opin. Drug. Saf. — 2008. — P. 481-489.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Hecht F. M., Busch M. P., Rawal B., Webb M., Rosenberg E., Swanson M. et al. Use of laboratory tests and clinical symptoms for identification of primary HIV infection // AIDS. — 2002. — № 16. — P. 1119-1129.</mixed-citation></ref></ref-list></back></article>
