Russian Family DoctorRussian Family Doctor2072-16682713-2331Eco-Vector143710.17816/RFD2015317-26Research ArticleDIAGNOSIS AND TREATMENT OF IRRITABLE BOWEL SYNDROME IN GENERAL PRACTICELebedevA Kanatoliy.lebedev@szgmu.ruNorth-Western State Medical University named after I. I. Mechnikov15092015193172616032016Copyright © 2015, Lebedev A.K.2015The guidelines present the classification, epidemiology, risk factors and risk groups of irritable bowel syndrome. Basic principles of clinical, laboratory and instrumental diagnostics in general practice, diagnostic criteria, principles of differential diagnosis are presented. The guidelines also present recommendations for pharmacological and non-pharmacological treatment in general practice.Clinical guidelines were approved at the meeting of the profile committee on general practice of the Ministry of Health of Russia on 10.13.2015.irritable bowel syndromegeneral practiceсиндром раздраженной кишкиобщая врачебная практика[Longstreth G.F., Thompson W.G., Chey W.D., et al. Functional Bowel Disorders // Gastroenterology. - 2006. - Vol. 130. - P. 1480-1491.][Ивашкин В.Т., Шелыгин Ю.А., Баранская Е.К., и др. Клинические рекомендации Российской гастроэнтерологической ассоциации, Ассоциации колопроктологов России по диагностике и лечению больных с синдромом раздраженного кишечника // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. - 2014. - Т. 24. - № 2. - С. 92-101.][Lovell R.M., Ford A.C. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis // Clin Gastroenterol Hepatol. - 2012. - Vol. 10. - № 7. - P. 712-721.][Brandt L.J., Chey W.D., Foxx-Orenstein A.E., et al. An evidence-based position statement on the management of irritable bowel syndrome. American College of Gastroenterology Task Force on Irritable Bowel Syndrome // Am J Gastroenterol. - 2009. - Vol. 104. - Suppl 1. - P. 1-35.][Гастроэнтерология. Национальное руководство: краткое издание / Под ред. В. Т. Ивашкина, Т. Л. Лапиной. - М.: ГЭОТАР-Медиа, 2011. - 480 с.][World Gastroenterology Organisation (WGO). World Gastroenterology Organisation Global Guideline: irritable bowel syndrome: a global perspective. Munich (Germany): World Gastroenterology Organisation (WGO). - 2009. - 20 p.][Wilkins T., Pepitone C., Alex B., Schade R.R. Diagnosis and Management of IBS in Adults // Am Fam Physician. - 2012. - Vol. 86. - № 5. - P. 419-426.][Saito Y.A., Petersen G.M., Larson J.J., et al. Familial aggregation of irritable bowel syndrome: a family case-control study // Am J Gastroenterol. - 2010. - Vol. 105. - № 4. - P. 833-841.][White D.L., Savas L.S., Daci K., et al. Trauma history and risk of the irritable bowel syndrome in women veterans // Aliment Pharmacol Ther. - 2010. - Vol. 32. - № 4. - P. 551-561.][Jones J., Boorman J., Cann P., et al. British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome // Gut. - 2000. - Vol. 47. - Suppl II. - P. 1-19.][An Evidence-Based Systematic Review on the Management of Irritable Bowel Syndrome American College of Gastroenterology Task Force on Irritable Bowel Syndrome // American Journal of Gastroenterology. - 2009. - Vol. 104. - Suppl. 1. - P. S1-S35.][National Collaborating Centre for Nursing and Supportive Care. Irritable bowel syndrome in adults. Diagnosis and management of irritable bowel syndrome in primary care. - London (UK): National Institute for Health and Clinical Excellence (NICE), 2008. - 553 p.][Spiller R., Aziz Q., Creed F., et al. Guidelines on the irritable bowel syndrome: mechanisms and practical management // Gut. - 2007. - Vol. 56. - № 12. - P. 1770-1798.][Irritable bowel syndrome in adults. Diagnosis and management of irritable bowel syndrome in primary care; February 2008 (revised 2014). NICE clinical guideline 61. - 32 р.][Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel. National Institute for Health and Clinical Excellence; October 2013. NICE diagnostics guidance 11. - 58 р.][Drossman D.A. The Functional Gastrointestinal Disorders and the Rome III Process // Gastroenterology. - 2006. - Vol. 130. - P. 1377-1390.][Wilkins T., Pepitone C., Alex B., Schade R.R. Diagnosis and Management of IBS in Adults // Am Fam Physician. - 2012. - Vol. 86. - № 5. - P. 419-426.][Saha L. Irritable bowel syndrome: Pathogenesis, diagnosis, treatment, and evidence-based medicine // World J Gastroenterol. - 2014. - Vol. 20. - № 22. - P. 6759-6773.]