Russian Family DoctorRussian Family DoctorРоссийский семейный врач2072-16682713-2331Eco-Vector21771710.17816/RFD217717Case reportКлинический случайResearch ArticleModification of the course of post-COVID syndrome associated with reactivation of chronic persistent Epstein−Barr virus infection and chronic nasopharyngotonsillitis of mixed etiologyМодификация течения постковидного синдрома, ассоциированная с реактивацией хронической персистирующей Эпштейна – Барр-вирусной инфекции и обострением хронического ринофаринготонзиллита смешанной этиологииhttps://orcid.org/0009-0003-7951-55081798-2618NeverovVladimir A.НеверовВладимир Александрович
Russian Federation

MD, Cand. Sci. (Med.), Assistant Professor

канд. мед. наук, доцент

v.neveroff@mail.ruNorth-Western State Medical University named after I.I. MechnikovСеверо-Западный государственный медицинский университет им. И.И. Мечникова220220231004202327151561102202322022023Copyright ©; 2023, Eco-VectorCopyright ©; 2023, Эко-ВекторCopyright ©; 2023,2023Eco-VectorЭко-Векторhttps://journals.eco-vector.com/RFD/article/view/217717

A wide range of symptoms that occur in patients with post-COVID syndrome can include both manifestations of the clinical consequences of COVID-19 and symptoms of an exacerbation of a chronic pathology that they had before the development of coronavirus infection. Correct assessment of clinical data can help determine the origin of the existing manifestations of the disease and build a plan for adequate diagnostic and therapeutic measures.

In the article, on the example of a clinical case, a variant of the modified (exacerbation of chronic pathology) course of the post-COVID syndrome was analyzed. An example of modern laboratory diagnostics of reactivation of chronic persistent Epstein–Barr virus infection and exacerbation of chronic nasopharyngotonsillitis of mixed viral-bacterial-mycotic etiology, developed against the background of post-COVID syndrome, is given. The principles of therapy for this comorbid condition are presented and explained.

Большой спектр симптомов, возникающих у пациентов с постковидным синдромом, может включать проявления как клинической картины последствий COVID-19, так и обострения хронической патологии, существовавшей до развития коронавирусной инфекции. Правильная оценка клинических данных может помочь определить происхождение проявлений заболевания и выстроить план адекватных диагностических и лечебных мероприятий.

В статье на примере клинического случая разобран вариант модифицированного (обострением хронической патологии) течения постковидного синдрома. Дан пример современной лабораторной диагностики реактивации хронической персистирующей Эпштейна – Барр-вирусной инфекции и обострения хронического ринофаринготонзиллита смешанной вирусно-бактериально-микотической этиологии, развившихся на фоне постковидного синдрома. Представлены и объяснены принципы терапии этого коморбидного состояния.

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