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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Family Doctor</journal-id><journal-title-group><journal-title xml:lang="en">Russian Family Doctor</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский семейный врач</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2072-1668</issn><issn publication-format="electronic">2713-2331</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">321284</article-id><article-id pub-id-type="doi">10.17816/RFD321284</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Review</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научный обзор</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Psychoemotional disorders of patients with inflammatory bowel diseases: prevalence, pathogenesis and treatment options</article-title><trans-title-group xml:lang="ru"><trans-title>Нарушения психоэмоционального статуса у пациентов с воспалительными заболеваниями кишечника: распространенность, патогенез и возможности терапии</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title/></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6151-2021</contrib-id><contrib-id contrib-id-type="scopus">6603812937</contrib-id><contrib-id contrib-id-type="researcherid">P-4453-2014</contrib-id><contrib-id contrib-id-type="spin">5283-2032</contrib-id><name-alternatives><name xml:lang="en"><surname>Bakulin</surname><given-names>Igor G.</given-names></name><name xml:lang="ru"><surname>Бакулин</surname><given-names>Игорь Геннадьевич</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>igbakulin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0134-8856</contrib-id><contrib-id contrib-id-type="spin">4965-6390</contrib-id><name-alternatives><name xml:lang="en"><surname>Stamboltsyan</surname><given-names>Venera Sh.</given-names></name><name xml:lang="ru"><surname>Стамболцян</surname><given-names>Венера Шаеновна</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>stamboltsyan95@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0844-4469</contrib-id><contrib-id contrib-id-type="spin">4981-9153</contrib-id><name-alternatives><name xml:lang="en"><surname>Oganezova</surname><given-names>Inna A.</given-names></name><name xml:lang="ru"><surname>Оганезова</surname><given-names>Инна Андреевна</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>oganezova@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">North-Western State Medical University named after I.I. Mechnikov</institution></aff><aff><institution xml:lang="ru">Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-05-23" publication-format="electronic"><day>23</day><month>05</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-07-20" publication-format="electronic"><day>20</day><month>07</month><year>2023</year></pub-date><volume>27</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>23</fpage><lpage>31</lpage><history><date date-type="received" iso-8601-date="2023-03-12"><day>12</day><month>03</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-03-14"><day>14</day><month>03</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023,</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/RFD/article/view/321284">https://journals.eco-vector.com/RFD/article/view/321284</self-uri><abstract xml:lang="en"><p>Inflammatory bowel diseases, which include Crohn’s disease and ulcerative colitis, according to the World Gastroenterological Organization occupy one of the leading places in the structure of diseases of the gastrointestinal tract of the rate of spread and relevance of research in most countries of the world. The currently existing therapy regimens, which are standardized depending on the form of the disease and the severity of the course, do not take into account the psycho-emotional component of the disease. Progressive course, frequent exacerbations, restriction of social activity, the presence of extra-intestinal manifestations and complications lead to early disability and significantly worsen the quality of life of patients with inflammatory bowel disease.</p></abstract><trans-abstract xml:lang="ru"><p>Воспалительные заболевания кишечника, включающие болезнь Крона и язвенный колит, по данным Всемирной гастроэнтерологической организации, в большинстве стран мира занимают одно из ведущих мест в структуре болезней желудочно-кишечного тракта по темпам распространения и актуальности исследований. В существующих в настоящее время схемах терапии, стандартизированных в зависимости от формы заболевания и тяжести течения, не учтен психоэмоциональный компонент. Прогрессирующее течение, частые обострения, ограничение социальной активности, наличие внекишечных проявлений и осложнений приводят к ранней инвалидизации и значимо ухудшают качество жизни пациентов с воспалительными заболеваниями кишечника.</p></trans-abstract><trans-abstract xml:lang="zh"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>inflammatory bowel disease</kwd><kwd>ulcerative colitis</kwd><kwd>Crohn’s disease</kwd><kwd>psycho-emotional state</kwd><kwd>brain-gut axis</kwd><kwd>quality of life</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>воспалительные заболевания кишечника</kwd><kwd>язвенный колит</kwd><kwd>болезнь Крона</kwd><kwd>психоэмоциональный статус</kwd><kwd>ось кишечник – мозг</kwd><kwd>качество жизни</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Inflammatory Bowel Disease [Internet]. World Gastroenterology Organisation. 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