Russian Family DoctorRussian Family DoctorРоссийский семейный врач2072-16682713-2331Eco-Vector43038410.17816/RFD430384LecturesЛекцииReview ArticleThe problem of toxoplasmosis in outpatient practice. Part I. Toxoplasmosis in immunocompetent patientsПроблема токсоплазмоза в амбулаторной практике. Часть II. Токсоплазмоз у иммунокомпетентных пациентовhttps://orcid.org/0000-0003-2579-279957192667926HPG-3481-20235644-9877VasilievValerii V.ВасильевВалерий Викторович
Russian Federation

MD, Dr. Sci. (Med.), Professor

д-р мед. наук, профессор

vcubed@ya.ruhttps://orcid.org/0000-0001-5378-38602558-9273KuznetsovNikolai I.КузнецовНиколай Ильич
Russian Federation

MD, Dr. Sci. (Med.), Professor

д-р мед. наук, профессор

meri-kuz-48@mail.ruhttps://orcid.org/0000-0002-3660-26664425738392-2950StartsevaGalina Yu.СтарцеваГалина Юрьевна
Russian Federation

MD, Cand. Sci. (Med.), Assistant Professor

канд. мед. наук, доцент

star661@rambler.ruNorth-Western State Medical University named after I.I. MechnikovСеверо-Западный государственный медицинский университет им. И.И. МечниковаPediatric Research and Clinical Center for Infectious Diseases of federal medical and biological agencyДетский научно-клинический центр инфекционных болезней федерального медико-биологического агентстваNorth-Western State Medical University named after I.I. MechnikovСеверо-Западный государственный медицинский университет им. И.И. Мечникова01062023200720232725101905202301062023Copyright ©; 2023, Eco-VectorCopyright ©; 2023, Эко-ВекторCopyright ©; 2023,2023Eco-VectorЭко-Векторhttps://creativecommons.org/licenses/by-nc-nd/4.0/https://journals.eco-vector.com/RFD/article/view/430384

Acute toxoplasmosis in immunocompetent persons most often proceeds subclinically and ends with the formation of latent toxoplasmosis, which does not require therapy and observation. The presence of clinical signs of a long-term disease forces an extensive diagnostic search to exclude/confirm chronic toxoplasmosis. In the treatment of toxoplasmosis in persons without immunodeficiency, repeated courses of antiprotozoal drugs are used, which do not guarantee clinical recovery and the absence of relapses. Perinatal aspects of toxoplasmosis will be discussed in a future publication.

Острый токсоплазмоз у иммунокомпетентных лиц чаще всего протекает субклинически и заканчивается формированием латентного токсоплазмоза без необходимости терапии и наблюдения. Наличие клинических признаков длительно протекающего заболевания обуславливает обширный диагностический поиск для исключения/подтверждения хронического токсоплазмоза. В лечении токсоплазмоза у лиц без иммунодефицита используют повторные курсы приема антипротозойных препаратов, не гарантирующие клинического выздоровления и отсутствия рецидивов. Перинатальные аспекты токсоплазмоза будут обсуждены в следующей публикации.

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