SURGICAL IMPLANTS WITH INCREASED OSTEOINDUCTIVITY BASED ON BIOCOMPOSITE AND CALCIUMPHOSPHATE MATRICES PRODUCED VIA 3D PROTOTYPING AND MODIFIED WITH RECOMBINANT PROTEIN GROWTH FACTORS FOR REGENERATIVE MEDICINE

  • Authors: Zaitsev VV1, Safronova TV2, Esipov RS3, Lukina Y.S4
  • Affiliations:
    1. Priorov National Medical Research Center of Traumatology and Orthopedics of the Ministry of Health of the Russian Federation
    2. Lomonosov Moscow State University
    3. Shemyakin-Ovchinnikov Institute of bioorganic chemistry of the Russian Academy of Sciences
    4. Dmitry Mendeleev University of Chemical Technology of Russia
  • Issue: Vol 38, No 2 (2019)
  • Pages: 6-10
  • Section: Articles
  • URL: https://journals.eco-vector.com/RMMArep/article/view/33801
  • DOI: https://doi.org/10.17816/rmmar33801
  • Cite item
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Abstract


Materials based on calcium phosphates and recombinant protein growth factors for surgical implant’s for solving problems of regenerative medicine are presented (bibliography: 4 refs).

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About the authors

V V Zaitsev

Priorov National Medical Research Center of Traumatology and Orthopedics of the Ministry of Health of the Russian Federation

Moscow, Russia

T V Safronova

Lomonosov Moscow State University

Moscow, Russia

R S Esipov

Shemyakin-Ovchinnikov Institute of bioorganic chemistry of the Russian Academy of Sciences

Moscow, Russia

Yu S Lukina

Dmitry Mendeleev University of Chemical Technology of Russia

Moscow, Russia

References

  1. Zaitsev V. V. Biocomposite osteoplastic materials based on biological, polymer and calcium phosphate matrices using modified supercritical and genetic engineering technologies for tissue engineering in regenerative medicine. Production technology, preclinical evaluation in model studies “in vitro” and “in vivo”. Materialy Х yubileynogo Vserossiyskogo s”ezda travmatologov-ortopedov, Moscow, 16-19 September 2014.
  2. Reddi A. H. BMPs: from bone morphogenetic proteins to body morphogenetic proteins. Cytokine Growth Factor Rev. 2005; 16: 249-50. doi: 10.1016/j.cytogfr.2005.04.003
  3. Safronova T. V., Putlyaev V. I. Powder Systems for Calcium Phosphate Ceramics. Inorganic Materials. 2017; 53 (1): 17-26. doi: 10.1134/S0020168516130057
  4. Belyakov A. V., Lukin E. S., Safronova T. V., Safina M. N., Putlyaev V. I. Porous materials made from calcium phosphates (Review). Glass and Ceramics. 2008; 65 (9-10): 337-9. doi: 10.1007/s10717-009-9086-x

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