Russian Military Medical Academy ReportsRussian Military Medical Academy Reports2713-23152713-2323Eco-Vector4334810.17816/rmmar43348Research ArticleANEMIA AS A MARKER OF RHEUMATIC DISEASE ACTIVITYLezinaA. S-ToporkovM. M-S.M. Kirov Military Medical Academy of the Ministry of Defense13122020391S778128082020Copyright © 2020, Lezina A.S., Toporkov M.M.2020Rheumatic diseases are often accompanied by changes in the blood system, including anemia. Anemia not only worsens the quality of life of patients, but also adversely affects the course of rheumatic disease. Therefore, the work has been studied assessed the degree of severity of anemia of rheumatic diseases, correlation between anemia and rheumatoid arthritis activity has been identified, and the effectiveness of basic anti-inflammatory therapy on anemia in patients was assessed rheumatoid arthritis. 99 patients diagnosed with non-differentiated arthritis aged 23 to 65 years were enrolled in the study. Among them were 79 women (79.8%), the average age was 52.3 ± 9.72 years, and 20 men (20.2%), the average age was 46 ± 19.6 years. All patients were tested for rheumatoid arthritis by DAS 28, hemograms, which included determination of hemoglobin concentration, erythrocytes, mean hemoglobin content in erythrocyte. 77 (77.7%) patients were examined in dynamics after 6 months with the same volume of clinical-laboratory methods. In the course of the study it is established that in rheumatoid arthritis, a sufficiently high degree of severity of anemia in the debut of the disease is detected. The higher the degree of disease activity, the higher the severity of anemia, including hypochromia. The application of the principles of "treatment before goal" with the appointment of adequate basic anti-inflammatory therapy allows achieving remission or low activity in more patients, which leads to a significant decrease in the frequency of occurrence of anemia syndrome.anemiaanemia of chronic diseaserheumatic diseaseactivity diseaserheumatoid arthritissystemic lupus erythematosusанемияанемия хронических заболеванийревматическое заболеваниеактивность заболеванияревматоидный артритсистемная красная волчанка[1. Воробьев, А.И. Руководство по гематологии / А.И. Воробьев. - М.: Ньюдиамед, 2002. - С.50-67.][2. Мазуров, В.И. Клиническая ревматология: Руководство для практических врачей / Под ред. В.И. Мазурова. - СПб.: Фолиант, 2001. - С.100-340.][3. Насонов, Е.Л. Ревматология: Российские клинические рекомендации / Под ред. Е.Л. Насонова. - М.: ГЭОТАР-Медиа, 2020. - С.104-130.][4. Богданов, А.Н. Изменения системы крови при ревматических заболеваниях / А.Н. Богданов [и др.] // Вестн. Росс. Воен.-мед. акад. 2013. - №2. - С.173-179.][5. Волков, К.Ю. Анемия хронических заболеваний в практике ревматолога: особенности патогенеза, диагностики, и дифференциаль-ной диагностики / К.Ю. Волков [и др.] // Клин. патофиз. Воен.-мед. акад. - 2018. - №24. - С.37-41.][6. Кулибаба, Т.Г. Гематологические синдромы при ревматических заболеваниях / Т.Г. Кулибаба // Медицина. XXI век (Санкт-Петербургский государственный университет, медицинский факультет). - 2006. - №4. - С.45-51.][7. Giannouli, S. Anaemia in systemic lupus erythematosus: from pathophysiology to clinical assessment / S. Giannouli [et al.] // Ann. rheum. dis. - 2006. - №2. - P.144-148.]