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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Military Medical Academy Reports</journal-id><journal-title-group><journal-title xml:lang="en">Russian Military Medical Academy Reports</journal-title><trans-title-group xml:lang="ru"><trans-title>Известия Российской Военно-медицинской академии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2713-2315</issn><issn publication-format="electronic">2713-2323</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">546120</article-id><article-id pub-id-type="doi">10.17816/rmmar546120</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Chorionic bump: ultrasound predictor of adverse pregnancy outcome</article-title><trans-title-group xml:lang="ru"><trans-title>Хориальное выпячивание: ультразвуковой предиктор неблагоприятного исхода беременности</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7383-512X</contrib-id><contrib-id contrib-id-type="spin">1450-5053</contrib-id><name-alternatives><name xml:lang="en"><surname>Zheleznyak</surname><given-names>Igor S.</given-names></name><name xml:lang="ru"><surname>Железняк</surname><given-names>Игорь Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., D.Sc. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>докт. мед. наук, профессор</p></bio><email>igzh@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0037-2854</contrib-id><contrib-id contrib-id-type="spin">2794-6820</contrib-id><name-alternatives><name xml:lang="en"><surname>Ryazanov</surname><given-names>Vladimir V.</given-names></name><name xml:lang="ru"><surname>Рязанов</surname><given-names>Владимир Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., D.Sc. (Medicine)</p></bio><bio xml:lang="ru"><p>докт. мед. наук, доцент</p></bio><email>79219501454@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6791-518X</contrib-id><contrib-id contrib-id-type="spin">3115-7430</contrib-id><name-alternatives><name xml:lang="en"><surname>Sadykova</surname><given-names>Gulnaz K.</given-names></name><name xml:lang="ru"><surname>Садыкова</surname><given-names>Гульназ Камальдиновна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Ph.D. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>kokonya1980@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9594-9822</contrib-id><contrib-id contrib-id-type="spin">1453-8437</contrib-id><name-alternatives><name xml:lang="en"><surname>Boykov</surname><given-names>Igor V.</given-names></name><name xml:lang="ru"><surname>Бойков</surname><given-names>Игорь Валерьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., D.Sc. (Medicine); Professor</p></bio><bio xml:lang="ru"><p>докт. мед. наук, профессор</p></bio><email>qwertycooolt@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-0446-5050</contrib-id><name-alternatives><name xml:lang="en"><surname>Glebov</surname><given-names>Sergey G.</given-names></name><name xml:lang="ru"><surname>Глебов</surname><given-names>Сергей Геннадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3<sup>rd</sup> year student</p></bio><bio xml:lang="ru"><p>студент 3-го курса</p></bio><email>sergey1990glebov@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1057-5048</contrib-id><name-alternatives><name xml:lang="en"><surname>Kuznetsova</surname><given-names>Natalya Yu.</given-names></name><name xml:lang="ru"><surname>Кузнецова</surname><given-names>Наталья Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Ph.D. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>kznnataly@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3677-8765</contrib-id><contrib-id contrib-id-type="spin">6793-1985</contrib-id><name-alternatives><name xml:lang="en"><surname>Latysheva</surname><given-names>Anastasiya Ya.</given-names></name><name xml:lang="ru"><surname>Латышева</surname><given-names>Анастасия Яковлевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Ph.D. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>vaska.petrova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0523-9411</contrib-id><contrib-id contrib-id-type="spin">8686-1597</contrib-id><name-alternatives><name xml:lang="en"><surname>Postanogov</surname><given-names>Roman A.</given-names></name><name xml:lang="ru"><surname>Постаногов</surname><given-names>Роман Анатольевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>radiologist; address</p></bio><bio xml:lang="ru"><p>врач-рентгенолог</p></bio><email>r.a.postanogov@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Military Medical Academy</institution></aff><aff><institution xml:lang="ru">Военно-медицинская академия</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский государственный педиатрический медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Scientific Research Institute of Pulmonology</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский институт пульмонологии</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-10-17" publication-format="electronic"><day>17</day><month>10</month><year>2023</year></pub-date><volume>42</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>303</fpage><lpage>309</lpage><history><date date-type="received" iso-8601-date="2023-07-13"><day>13</day><month>07</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-07-24"><day>24</day><month>07</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/RMMArep/article/view/546120">https://journals.eco-vector.com/RMMArep/article/view/546120</self-uri><abstract xml:lang="en"><p>For the first time R. Harris et al. in 2006 a chorionic bump was described, detected by ultrasound examination in the first trimester of pregnancy, having characteristic ultrasound signs and localization. Modern knowledge about the etiology and clinical significance of chorionic bump for predicting the outcome of pregnancy is insufficient and contradictory. Inconsistency of the data may be due to the rarity of occurrence, a small sample of the studied groups, the lack of histopathological studies. Among doctors who make ultrasound investigations there is a low awareness of chorionic bump and as a result an erroneous interpretation of sonography data. Nevertheless, there is more and more evidence that this sign is a predictor of an adverse outcome of pregnancy. Doctors who make ultrasound investigations in the first trimester of pregnancy should be aware of the chorionic bump and be able to differentiate it with other pathological conditions. If a chorionic bump is detected, ultrasound examination in dynamics should be recommended. Based on the study of domestic and foreign literature, this scientific review presents modern ideas about the pathomorphology of chorionic bump, informations about significance in terms of predicting the outcome of pregnancy, and the main aspects of ultrasound diagnostics and differential diagnosis of this pathology.</p></abstract><trans-abstract xml:lang="ru"><p>В 2006 г. R. Harris et al. впервые описали хориальное выпячивание, выявляемое при ультразвуковом исследовании в первом триместре беременности, имеющее характерные ультразвуковые признаки и локализацию. Современные знания об этиологии и клиническом значении хориального выпячивания для прогноза исхода беременности недостаточны и противоречивы. Их противоречивость может быть обусловлена редкой встречаемостью, малой выборкой исследуемых групп, отсутствием гистопатологических исследований. Среди врачей, проводящих ультразвуковое исследование, отмечаются низкая осведомленность о хориальном выпячивании и, как следствие, ошибочная интерпретация сонографических данных. Тем не менее появляется все больше доказательств того, что этот признак является предиктором неблагоприятного исхода беременности. Врачи, проводящие ультразвуковое исследование в первом триместре беременности, должны знать о хориальном выпячивании и уметь дифференцировать его от других патологических состояний. При выявлении хориального выпячивания следует рекомендовать ультразвуковое исследование в динамике. На основании изучения отечественной и зарубежной литературы в настоящем научном обзоре приведены современные представления о патоморфологии хориального выпячивания, данные о его значимости с точки зрения прогноза исхода беременности, а также основные аспекты ультразвуковой и дифференциальной диагностики этой патологии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>choriodecidual tissue</kwd><kwd>chorionic bump</kwd><kwd>fertilized egg</kwd><kwd>outcome</kwd><kwd>predictor</kwd><kwd>pregnancy</kwd><kwd>ultrasound examination</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>исход</kwd><kwd>плодное яйцо</kwd><kwd>предиктор</kwd><kwd>ультразвуковое исследование</kwd><kwd>хориальное выпячивание</kwd><kwd>хориодецидуальная ткань</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Harris RD, Couto C, Karpovsky C, et al. 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