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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Military Medical Academy Reports</journal-id><journal-title-group><journal-title xml:lang="en">Russian Military Medical Academy Reports</journal-title><trans-title-group xml:lang="ru"><trans-title>Известия Российской Военно-медицинской академии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2713-2315</issn><issn publication-format="electronic">2713-2323</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">609540</article-id><article-id pub-id-type="doi">10.17816/rmmar609540</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Medical and social consequences of confusion syndrome that developed in the acute period of ischemic stroke</article-title><trans-title-group xml:lang="ru"><trans-title>Медицинские и социальные последствия синдрома спутанности сознания, развившегося в остром периоде ишемического инсульта</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5620-5986</contrib-id><contrib-id contrib-id-type="scopus">53663593100</contrib-id><contrib-id contrib-id-type="spin">8208-5103</contrib-id><name-alternatives><name xml:lang="en"><surname>Khlystov</surname><given-names>Yuriy V.</given-names></name><name xml:lang="ru"><surname>Хлыстов</surname><given-names>Юрий Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>assistant to the Head of the Сlinic</p></bio><bio xml:lang="ru"><p>помощник начальника клиники</p></bio><email>khlysyura@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5881-2242</contrib-id><contrib-id contrib-id-type="scopus">37066611200</contrib-id><contrib-id contrib-id-type="researcherid">H-9132-2016</contrib-id><contrib-id contrib-id-type="spin">1006-2845</contrib-id><name-alternatives><name xml:lang="en"><surname>Tsygan</surname><given-names>Nikolay V.</given-names></name><name xml:lang="ru"><surname>Цыган</surname><given-names>Николай Васильевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., D.Sc. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>докт. мед. наук, профессор</p></bio><email>1860n@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3756-6214</contrib-id><contrib-id contrib-id-type="spin">6439-6701</contrib-id><name-alternatives><name xml:lang="en"><surname>Kolomentsev</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Коломенцев</surname><given-names>Сергей Витальевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., PhD (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>skolomencev@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3616-6574</contrib-id><contrib-id contrib-id-type="spin">4961-0342</contrib-id><name-alternatives><name xml:lang="en"><surname>Kurasov</surname><given-names>Evgeny S.</given-names></name><name xml:lang="ru"><surname>Курасов</surname><given-names>Евгений Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., D.Sc. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>докт. мед. наук, профессор</p></bio><email>doc4678@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7314-7711</contrib-id><contrib-id contrib-id-type="scopus">7003327776</contrib-id><contrib-id contrib-id-type="researcherid">I-6024-2016</contrib-id><contrib-id contrib-id-type="spin">1155-9732</contrib-id><name-alternatives><name xml:lang="en"><surname>Odinak</surname><given-names>Miroslav M.</given-names></name><name xml:lang="ru"><surname>Одинак</surname><given-names>Мирослав Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Corresponding Member of the Russian Academy of Sciences, D.Sc. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>чл.-корр. РАН, докт. мед. наук, профессор</p></bio><email>odinak@rambler.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8988-3011</contrib-id><contrib-id contrib-id-type="scopus">35734354000</contrib-id><contrib-id contrib-id-type="researcherid">F-9120-2013</contrib-id><contrib-id contrib-id-type="spin">6112-2792</contrib-id><name-alternatives><name xml:lang="en"><surname>Litvinenko</surname><given-names>Igor' V.</given-names></name><name xml:lang="ru"><surname>Литвиненко</surname><given-names>Игорь Вячеславович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., D.Sc. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>докт. мед. наук, профессор</p></bio><email>litvinenkoiv@rambler.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Military Medical Academy</institution></aff><aff><institution xml:lang="kk"></institution></aff><aff><institution xml:lang="pt"></institution></aff><aff><institution xml:lang="ru">Военно-медицинская академия</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Military Medical Academy</institution></aff><aff><institution xml:lang="ru">Военно-медицинская академия</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-12-09" publication-format="electronic"><day>09</day><month>12</month><year>2023</year></pub-date><volume>42</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>377</fpage><lpage>382</lpage><history><date date-type="received" iso-8601-date="2023-10-14"><day>14</day><month>10</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-10-20"><day>20</day><month>10</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/RMMArep/article/view/609540">https://journals.eco-vector.com/RMMArep/article/view/609540</self-uri><abstract xml:lang="en"><p><bold>AIM</bold>: To assess the dynamics of cognitive functions in patients in whom the acute period of ischemic stroke was accompanied by the confusion syndrome, in comparison with patients in whom the acute period of stroke was not accompanied by the development of confusion. To assess the impact of clinical features of confusion syndrome on the development of post-stroke cognitive impairment, mortality, and patient care burden.</p> <p><bold>MATERIALS AND METHODS</bold>: The study involved 99 patients, 55 of whom developed severe confusion during the acute period of stroke, and 44 patients whose ischemic stroke was not complicated by the development of confusion syndrome. The groups were homogeneous in terms of the main etiological factors: age, degree of pre-stroke cognitive impairment. The study assessed the impact of the development of confusional syndrome on the outcome.</p> <p><bold>RESULTS</bold>: Confusion syndrome that develops in the acute period of ischemic stroke significantly increases the risk of developing or worsening existing cognitive impairment, mortality, dependence on care, and the burden on caregivers.</p> <p><bold>CONCLUSION</bold>: Being a serious complication, confusion syndrome requires monitoring of qualitative and quantitative indicators of consciousness in the acute period of ischemic stroke, prevention and, if detected, immediate correction of confusion syndrome.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель</bold>. Провести оценку динамики когнитивных функций у пациентов, у которых острый период ишемического инсульта сопровождался развитием синдрома спутанности сознания, в сравнении с пациентами, у которых тот же период не сопровождался развитием этого синдрома. Изучить влияние клинических особенностей синдрома спутанности сознания на развитие постинсультных когнитивных нарушений, смертность, нагрузку по уходу за пациентами.</p> <p><bold>Материалы и методы</bold>. В исследовании приняли участие 99 пациентов, у 55 из которых в остром периоде инсульта развилась выраженная спутанность сознания, а у 44 пациентов ишемический инсульт не осложнялся развитием этого синдрома. Группы были однородны по основным этиологическим показателям: полу, возрасту, степени доинсультных когнитивных нарушений. В ходе исследования проведена оценка влияния развития синдрома спутанности сознания на исход заболевания.</p> <p><bold>Результаты</bold>. Синдром спутанности сознания, развившийся в остром периоде ишемического инсульта, значимо повышает риск развития или усугубления имеющихся когнитивных нарушений, смертности, зависимость от ухода и нагрузку на лиц, ухаживающих за пациентом.</p> <p><bold>Заключение</bold>. Являясь серьезным осложнением, синдром спутанности сознания требует проведения мониторинга количественных и качественных показателей уровня сознания в остром периоде ишемического инсульта, профилактики и, при выявлении, незамедлительной коррекции этого синдрома.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cognition disorders</kwd><kwd>confusion syndrome</kwd><kwd>delirium</kwd><kwd>dementia</kwd><kwd>ischemic stroke</kwd><kwd>mortality</kwd><kwd>nurse</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>делирий</kwd><kwd>деменция</kwd><kwd>ишемический инсульт</kwd><kwd>когнитивные нарушения</kwd><kwd>синдром спутанности сознания</kwd><kwd>смертность</kwd><kwd>уход</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Dahl MH, Ronning OM, Thommessen B. Delirium in acute stroke — prevalence and risk factors. Acta Neurol Scand Suppl. 2010;22(190):39–43. 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