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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cardiac Arrhythmias</journal-id><journal-title-group><journal-title xml:lang="en">Cardiac Arrhythmias</journal-title><trans-title-group xml:lang="ru"><trans-title>Cardiac Arrhythmias</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Cardiac Arrhythmias</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2782-4284</issn><issn publication-format="electronic">2782-4233</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">111979</article-id><article-id pub-id-type="doi">10.17816/cardar111979</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Research</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Incidence of Coronary Embolism in Group of Patients with Atrial Fibrillation and Myocardial Infarction</article-title><trans-title-group xml:lang="ru"><trans-title>Встречаемость коронарной эмболии у пациентов с фибрилляцией предсердий, перенесших инфаркт миокарда</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title/></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3335-4986</contrib-id><contrib-id contrib-id-type="spin">7355-6689</contrib-id><name-alternatives><name xml:lang="en"><surname>Soloveva</surname><given-names>Mariia V.</given-names></name><name xml:lang="ru"><surname>Соловьева</surname><given-names>Мария Владимировна</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>cardiologist, assistant of the department of faculty therapy</p></bio><bio xml:lang="ru"><p>врач-кардиолог, ассистент кафедры факультетской терапии</p></bio><email>morethantea@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1898-084X</contrib-id><contrib-id contrib-id-type="spin">3716-3375</contrib-id><name-alternatives><name xml:lang="en"><surname>Boldueva</surname><given-names>Svetlana A.</given-names></name><name xml:lang="ru"><surname>Болдуева</surname><given-names>Светлана Афанасьевна</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедры факультетской терапии</p></bio><email>svetlanaboldueva@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">North-Western State Medical University named after I.I. Mechnikov</institution></aff><aff><institution xml:lang="ru">Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-12-24" publication-format="electronic"><day>24</day><month>12</month><year>2022</year></pub-date><volume>2</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>31</fpage><lpage>38</lpage><history><date date-type="received" iso-8601-date="2022-10-18"><day>18</day><month>10</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-11-17"><day>17</day><month>11</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2022,</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/cardar/article/view/111979">https://journals.eco-vector.com/cardar/article/view/111979</self-uri><abstract xml:lang="en"><p>Embolic myocardial infarction (EMI) is more common than gets to be diagnosed. EMI is often associated with atrial fibrillation (AF). The incidence of this pathology, prognosis and treatment tactics remain unclear.</p> <p><bold><italic>AIM:</italic></bold> To assess the incidence of EMI among patients with myocardial infarction (MI), genesis of coronary embolism (CE), initial characteristics, treatment and prognosis in group of patients with EMI.</p> <p><bold><italic>MATERIALS AND METHODS:</italic></bold> The group of patients with EMI was selected among 1989 patients with MI admitted to the cardiology department of the North-Western State Medical University named after I.I. Mechnikov between 2013 to December 2019. The CE verification criteria were the SUITA criteria. Statistical data processing was carried out using the SAS program.</p> <p><bold><italic>RESULTS:</italic></bold> 16 cases of EMI were registered (0.8% of all MI and 4.3% of patients with MI and AF). 68.7% (95% CI = 41.5%–88.9%) of patients with EMI had AF. All patients with EMI and AF did not have adequate anticoagulant therapy before admission. Among patients with EMI, men predominated, they were younger, had fewer comorbidities than patients with MI and without AF. 13 of 16 patients with EMI were prescribed anticoagulants. During hospitalization, the composite endpoint (pulmonary embolism + stroke + cardiovascular death) was recorded in 25% (95% CI = 7.3%–52.2%), in the long-term period — in 30% of cases (95 % CI = 6.7–65.2). All these patients had AF. EMI in patients with AF was associated with the development of severe chronic heart failure (CHF) by the time of discharge and with decompensation of CHF in the long-term period.</p> <p><bold><italic>CONCLUSIONS:</italic></bold> EMI often occur in group of patients with AF, always in the absence of adequate anticoagulant therapy. Patients with EMI and AF have a worse prognosis due to recurrent thromboembolic events.</p> <p>Keywords: anticoagulants; atrial fibrillation; coronary embolism; embolic myocardial infarction; prognosis; thrombaspiration.</p></abstract><trans-abstract xml:lang="ru"><p><bold><italic>Актуальность.</italic></bold> Эмбологенный инфаркт миокарда (ЭИМ) встречается гораздо чаще, чем диагностируется. Наиболее распространенными признаны ЭИМ, ассоциированные с фибрилляцией предсердий (ФП). Однако реальная встречаемость данной патологии, прогноз, а также тактика лечения остаются до конца неясными.</p> <p><bold><italic>Цель</italic></bold> — оценить встречаемость ЭИМ среди больных с инфарктом миокарда (ИМ), генез коронарной эмболии (КЭ), исходные характеристики больных с ЭИМ, особенности лечения пациентов с ЭИМ, прогноз.</p> <p><bold><italic>Материалы</italic></bold> <bold><italic>и</italic></bold> <bold><italic>методы.</italic></bold> В период с 1 января 2013 по 31 декабря 2019 г. среди 1989 пациентов, поступивших в кардиологическое отделение СЗГМУ им. И.И. Мечникова с диагнозом ИМ, была отобрана группа больных с ЭИМ. Критериями верификации КЭ являлись критерии SUITA. Статистическая обработка данных проведена в программе SAS.</p> <p><bold><italic>Результаты.</italic></bold> Зарегистрировано 16 случаев ЭИМ (0,8% от числа всех ИМ и 4,3% от больных с ИМ и ФП). ЭИМ чаще развивался у пациентов с ФП ― в 68,7% случаев (95% ДИ = 41,5%–88,9%). Все больные с ЭИМ и ФП до госпитализации не получали адекватной антикоагулянтной терапии. Среди пациентов с ЭИМ преобладали мужчины, они были моложе, имели меньше сопутствующих заболеваний по сравнению с больными с ИМ без ФП. 13 из 16 пациентов с ЭИМ были назначены антикоагулянты. В ходе госпитализации комбинированная конечная точка (тромбоэмболия легочной артерии + инсульт + сердечно-сосудистая смертность) была зарегистрирована у 25% больных (95% ДИ = 7,3%–52,2%), в отдаленном периоде — у 30% пациентов (95% ДИ = 6,7–65,2). Все эти больные имели ФП. ЭИМ у пациентов с ФП были ассоциированы с развитием тяжелой хронической сердечной недостаточности (ХСН) к моменту выписки, а также с декомпенсацией ХСН в отдаленном периоде.</p> <p><bold><italic>Заключение.</italic></bold> ЭИМ чаще развивается у пациентов с ФП, всегда при отсутствии адекватной антикоагулянтной терапии. Пациенты с ЭИМ и ФП имеют неблагоприятный прогноз, обусловленный рецидивирующими тромбоэмболическими событиями.</p> <p>Ключевые слова: антикоагулянты; коронарная эмболия; прогноз; тромбаспирация; фибрилляция предсердий; эмбологенный инфаркт миокарда.</p></trans-abstract><trans-abstract xml:lang="zh"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>anticoagulants</kwd><kwd>atrial fibrillation</kwd><kwd>coronary embolism</kwd><kwd>embolic myocardial infarction</kwd><kwd>prognosis</kwd><kwd>thrombaspiration</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>антикоагулянты</kwd><kwd>коронарная эмболия</kwd><kwd>прогноз</kwd><kwd>тромбаспирация</kwd><kwd>фибрилляция предсердий</kwd><kwd>эмбологенный инфаркт миокарда</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Frolov AA, Sharabrin EG, Savenkov AG, Botova SN. 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