IRREVERSIBLE ELECTROPORATION OF COLORECTAL LIVER METASTASES WITH THE "NANOKNIFE" SYSTEM

Abstract

Due to recent advances in minimally invasive surgery, there is a new ablation technique – the irre-versible electroporation (IRE), based on the effect of electric fields. This report describes the firstcase of colorectal liver metastases irreversible electroporation in Russian Federation. This early analysis of IRE treatment of hepatic tumors demonstrates safety for treating liver malignancies. Larger studies and longer follow-up are necessary to determine long-term efficacy.

Full Text

НЕОБРАТИМАЯ ЭЛЕКТРОПОРАЦИЯ МЕТАСТАЗОВ КОЛОРЕКТАЛЬНОГО РАКА В ПЕЧЕНЬС ИСПОЛЬЗОВАНИЕМ СИСТЕМЫ "NANOKNIFE"
×

References

  1. Weaver JC, Vaughan TE, Chizmadzhev Y. Theory of skin electroporation: implications of straight-through aqueous pathway segments that connect adjacent corneocytes. J Investig Dermatol Symp Proc. 1998 Aug; 3(2):143-7.
  2. Martin RC 2nd, McFarland K, Ellis S, Velanovich V. Irreversible electroporation therapy in the management of locally advanced pancreatic adenocarcinoma. J Am Coll Surg. 2012 Sep;215(3):361-9. Клиническая практика №1, 2013 http://clinpractice.ru 41 Новые технологии
  3. Davalos RV, Mir IL, Rubinsky B. Tissue ablation with irreversible electroporation. Ann Biomed Eng. 2005 Feb; 33(2):223-31.
  4. Thomson KR, Cheung W, Ellis SJ, et al. Investigation of the safety of irreversible electroporation in humans. J Vasc Interv Radiol. 2011 May; 22(5): 611-21.
  5. Mulier S, Mulier P, Ni Y, et al. Complications of radiofrequency coagulation of liver tumours. Br J Surg. 2002; 89: 1206-22.
  6. Livraghi T, SolbiatiL, Meloni MF, et al. Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology. 2003; 226: 441-51.
  7. Livraghi T, Meloni F, Solbiati L, et al. Complications of microwave ablation for liver tumors: results of a multicenter study. Cardiovasc Interv Radiol. 2012 Aug;35(4):868-74.
  8. Rhim H, Yoon KH, Lee JM, et al. Major complications after radio-frequency thermal ablation of hepatic tumors: spectrum of imaging findings. Radiographics 2003;23:123-134; disc 134-136.
  9. Lee EW, Chen C, Prieto VE, et al. Advanced hepatic ablation technique for creating complete cell death: irreversible electroporation. Radiology. 2010; 255: 426-33.
  10. Rubinsky B, Onik G, Mikus P. Irreversible electroporation: a new ablation modality-clinical implications. Technol Cancer Res Treat. 2007;6:37-48.
  11. Guo Y, Zhang Y, Klein R, et al. Irreversible electroporation therapy in the liver: longitudinal efficacy studies in a rat model of hepatocellular carcinoma. Cancer Res. 2010; 70:1555-63.
  12. Kingham TP, Karkar AM, D'Angelica MI, et al. Ablation of Perivascular Hepatic Malignant Tumors with Irreversible Electroporation. J Am Coll Surg. 2012 Sep;215(3):379-87.

Statistics

Views

Abstract: 237

PDF (Russian): 151

Cited-by

CrossRef: 3

  1. Vetshev PS, Chzhao AV, Ionkin DA, Stepanova YA, Zhavoronkova OI, Kulezneva YV, et al. Minimally invasive technologies for ablation of pancreatic malignancies. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2019;24(3):87. doi: 10.16931/1995-5464.2019387-98
  2. Ulashchik VS. Electroporation: characteristics and therapeutic application of the method (a review). Voprosy kurortologii, fizioterapii i lechebnoi fizicheskoi kul'tury. 2016;93(4):66. doi: 10.17116/kurort201646-73
  3. Astakhov DA, Panchenkov DN, Ivanov YV, Shablovsky OR, Kedrova AG, Soloviev NA, et al. Irreversible electroporation for locally advanced pancreatic cancer. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2018;23(2):59. doi: 10.16931/1995-5464.2018259-68

Article Metrics

Metrics Loading ...

PlumX


Copyright (c) 2013 Panchenkov D.N., Ivanov Y.V., Pikunov D.Y., Zabozlaev F.G., Nechunaev A.A., Kochieva M.P., Aleksanyan G.B.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies